SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5isv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 105
PHE A  25
PRO A  26
 None
 0.87A 3zoaB-5isvA:
undetectable		 3zoaB-5isvA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A  85
ILE A  89
LEU A 118
TYR A 115
 None
 0.96A 4w5nA-5isvA:
undetectable		 4w5nA-5isvA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A  83
LEU A  85
THR A  57
ALA A  55
ALA A  53
 None
 1.16A 4x1iB-5isvA:
undetectable		 4x1iB-5isvA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A  83
LEU A  85
THR A  57
VAL A  71
ALA A  53
 None
 1.02A 4x1iB-5isvA:
undetectable		 4x1iB-5isvA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE
(Escherichia
coli) 		6 / 12 LEU A  45
ALA A  83
LEU A  85
THR A  57
VAL A  71
ALA A  53
 None
 1.42A 4x20B-5isvA:
undetectable		 4x20B-5isvA:
15.45