SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5it6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		3 / 3 VAL A  47
ALA A  48
HIS A 113
 None
 0.69A 1q23G-5it6A:
undetectable		 1q23G-5it6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		3 / 3 VAL A  47
ALA A  48
HIS A 113
 None
 0.59A 1q23J-5it6A:
undetectable		 1q23J-5it6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		5 / 11 ALA A  48
ASP A  46
ILE A  33
ILE A   8
ILE A 121
 None
 1.14A 3s53B-5it6A:
undetectable		 3s53B-5it6A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A  62
GLY A  32
PHE A  31
SER A  34
 EDO  A 206 ( 3.6A)
PGE  A 205 ( 3.1A)
None
PGE  A 205 ( 3.5A)
 1.03A 3tzfB-5it6A:
undetectable		 3tzfB-5it6A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		5 / 12 LEU A  51
PHE A 102
GLU A  91
VAL A  90
HIS A 113
 None
EDO  A 207 ( 3.8A)
EDO  A 207 ( 3.3A)
None
None
 1.21A 4hvcB-5it6A:
undetectable		 4hvcB-5it6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		5 / 12 LEU A  51
PHE A 102
GLU A  91
VAL A  90
HIS A 113
 None
EDO  A 207 ( 3.8A)
EDO  A 207 ( 3.3A)
None
None
 1.21A 4q15A-5it6A:
undetectable		 4q15A-5it6A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		5 / 12 GLY A 128
SER A  30
PHE A  80
PHE A  88
VAL A  90
 PGE  A 205 (-2.9A)
PGE  A 205 (-2.8A)
None
None
None
 1.26A 6a94A-5it6A:
undetectable		 6a94A-5it6A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5it6 GALECTIN-RELATED
PROTEIN
(Gallus
gallus) 		4 / 7 GLY A  10
HIS A 113
GLU A  95
GLY A  15
 None
 0.97A 6n7fA-5it6A:
undetectable		 6n7fA-5it6A:
20.30