SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5itq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		5 / 12 PHE A 101
LEU A  60
ALA A  20
CYH A  18
VAL A  14
 None
 1.34A 2g72A-5itqA:
undetectable		 2g72A-5itqA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		3 / 3 GLU A 163
LEU A 166
ASP A 167
 None
 0.46A 3ko0A-5itqA:
undetectable		 3ko0A-5itqA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		3 / 3 GLU A 163
LEU A 166
ASP A 167
 None
 0.43A 3ko0T-5itqA:
1.9		 3ko0T-5itqA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		4 / 5 LEU A 166
ILE A 161
PRO A 160
PHE A 191
 None
 1.17A 3s3vA-5itqA:
undetectable		 3s3vA-5itqA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		4 / 6 GLU A  28
PHE A  23
THR A 103
TYR A 102
 None
 1.40A 5lrbA-5itqA:
undetectable		 5lrbA-5itqA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens) 		4 / 5 ARG A 179
ALA A 180
TYR A 263
GLN A 272
 None
 1.21A 6g9bA-5itqA:
undetectable
6g9bB-5itqA:
undetectable		 6g9bA-5itqA:
14.18
6g9bB-5itqA:
13.77