SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5iuj SENSOR HISTIDINE
KINASE DESK
(Bacillus
subtilis) 		4 / 8 PHE A 264
VAL A 305
MET A 363
ILE A 316
 None
 1.06A 4a97I-5iujA:
3.1		 4a97I-5iujA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5iuj SENSOR HISTIDINE
KINASE DESK
(Bacillus
subtilis) 		4 / 8 VAL A 318
TYR A 266
VAL A 294
ILE A 253
 None
None
ACP  A 401 ( 4.0A)
None
 1.15A 4aftD-5iujA:
undetectable
4aftE-5iujA:
undetectable		 4aftD-5iujA:
19.92
4aftE-5iujA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 5iuj SENSOR HISTIDINE
KINASE DESK
(Bacillus
subtilis) 		4 / 6 LEU A 250
LEU A 246
GLU A 249
ILE A 316
 None
 0.97A 4ww7A-5iujA:
undetectable		 4ww7A-5iujA:
21.43