SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		3 / 3 GLN A 626
TYR B 123
ARG B 124
 None
 0.90A 1gtbA-5iv9A:
undetectable		 1gtbA-5iv9A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 4 SER B  81
ILE B  82
VAL B 122
THR A 614
 None
 1.04A 1u70A-5iv9B:
undetectable		 1u70A-5iv9B:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 PHE A 146
TYR A 116
HIS A 165
VAL A  93
 None
 1.40A 1wu8A-5iv9A:
undetectable
1wu8C-5iv9A:
undetectable		 1wu8A-5iv9A:
15.92
1wu8C-5iv9A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		5 / 12 GLY A 419
GLY A 421
LEU A 423
GLY A 465
ARG A 484
 None
 1.05A 1y4lA-5iv9A:
undetectable		 1y4lA-5iv9A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 8 THR A 610
PHE B 127
ALA B  96
GLN A 507
 None
 1.07A 2ij7C-5iv9A:
undetectable		 2ij7C-5iv9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae) 		4 / 5 LEU B  77
LEU B 109
MET B  36
THR B 120
 None
 1.34A 2oaxD-5iv9B:
undetectable		 2oaxD-5iv9B:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		5 / 12 GLY A 553
ILE A 599
ALA A 609
ASP A 509
THR A 532
 None
 1.12A 2vdvE-5iv9A:
undetectable		 2vdvE-5iv9A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		5 / 11 GLY A 553
ILE A 599
ALA A 609
ASP A 509
THR A 532
 None
 1.12A 2vdvF-5iv9A:
undetectable		 2vdvF-5iv9A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 8 THR A 681
ASP A 678
TYR A 650
TRP A 711
 None
 1.41A 2xz5A-5iv9A:
undetectable
2xz5C-5iv9A:
undetectable		 2xz5A-5iv9A:
15.17
2xz5C-5iv9A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		5 / 12 GLY A 553
ILE A 599
ALA A 609
ASP A 509
THR A 532
 None
 1.18A 3ckkA-5iv9A:
undetectable		 3ckkA-5iv9A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		3 / 3 THR A 614
LYS B 158
GLU A 616
 None
 0.91A 3ijdB-5iv9A:
undetectable		 3ijdB-5iv9A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 8 GLU B 146
GLN A 486
ARG A 515
ASP A 516
 None
 0.96A 3mjrD-5iv9B:
undetectable		 3mjrD-5iv9B:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		3 / 3 GLN A 507
PHE B 127
TYR A 636
 None
 0.99A 3ucjB-5iv9A:
undetectable		 3ucjB-5iv9A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		4 / 6 GLN A 369
ARG A 405
ASP B 141
LEU A 522
 None
 1.08A 4ax8A-5iv9A:
undetectable		 4ax8A-5iv9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 6 ASP A 371
SER A 336
ALA A 366
PHE A 393
 None
 0.88A 4nedA-5iv9A:
undetectable		 4nedA-5iv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		3 / 3 PRO A 401
MET A 400
TYR A 442
 None
 1.00A 4qa0B-5iv9A:
undetectable		 4qa0B-5iv9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		3 / 3 PRO A 401
MET A 400
TYR A 442
 None
 1.04A 4qa0A-5iv9A:
undetectable		 4qa0A-5iv9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		3 / 3 MET A 746
GLN A 687
TYR A 675
 None
 1.08A 4udcA-5iv9A:
undetectable		 4udcA-5iv9A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 8 ARG A 243
ASP A 277
ASP A 314
ASP A 318
 None
 1.16A 4xqgA-5iv9A:
undetectable		 4xqgA-5iv9A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.32A 5a06A-5iv9A:
undetectable		 5a06A-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.29A 5a06B-5iv9A:
undetectable		 5a06B-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.32A 5a06C-5iv9A:
undetectable		 5a06C-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.32A 5a06D-5iv9A:
undetectable		 5a06D-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.32A 5a06E-5iv9A:
undetectable		 5a06E-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 7 ARG A 358
PHE A 319
ARG A 243
ASP A 271
 None
 1.29A 5a06F-5iv9A:
undetectable		 5a06F-5iv9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		5 / 12 MET B 147
ILE B 143
ASP A 584
VAL B 122
GLY A 613
 None
 1.25A 5igiA-5iv9B:
undetectable		 5igiA-5iv9B:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		5 / 12 PHE B  90
GLY A 710
GLY B  93
ASN A 317
ASP A 314
 None
 1.06A 5kpcB-5iv9B:
undetectable		 5kpcB-5iv9B:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
(Klebsiella
pneumoniae) 		4 / 6 ASP A 602
ASP A 584
ASN A 612
GLN A 507
 None
 1.21A 5l6eA-5iv9A:
undetectable		 5l6eA-5iv9A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_1
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		4 / 4 ASP B 141
ALA A 305
SER A 336
PHE A 353
 None
 1.50A 6cm4A-5iv9B:
0.1		 6cm4A-5iv9B:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		4 / 6 LEU A 506
GLY A 512
ARG A 515
ARG B 124
 None
 1.17A 6gtqB-5iv9A:
undetectable
6gtqD-5iv9A:
undetectable		 6gtqB-5iv9A:
12.90
6gtqD-5iv9A:
5.01