SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_1
(DIHYDROFOLATE
REDUCTASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 4 GLU B 112
ASN A 564
ARG A 567
THR A 170
None
1.42A 1drfA-5ivaB:
undetectable
1drfA-5ivaB:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 10 ARG A  86
THR A 162
GLY A 609
THR A  58
THR A  55
None
None
C8E  A 702 ( 4.0A)
None
None
1.34A 1gtfG-5ivaA:
undetectable
1gtfH-5ivaA:
undetectable
1gtfG-5ivaA:
8.31
1gtfH-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 11 GLY A 609
THR A  58
THR A  55
ARG A  86
THR A 162
C8E  A 702 ( 4.0A)
None
None
None
None
1.33A 1gtfU-5ivaA:
undetectable
1gtfV-5ivaA:
undetectable
1gtfU-5ivaA:
8.31
1gtfV-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 ASP A 201
ASP A 257
LEU A 260
LEU A 196
None
0.87A 1nh8A-5ivaA:
undetectable
1nh8A-5ivaA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 6 PHE A 572
ALA A 557
LEU A 556
ILE A 546
None
C8E  A 701 ( 4.1A)
None
None
1.06A 1sbrA-5ivaA:
undetectable
1sbrB-5ivaA:
undetectable
1sbrA-5ivaA:
14.26
1sbrB-5ivaA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
3 / 3 TYR A 299
ARG A 207
GLN B 120
None
0.60A 1tw4A-5ivaA:
1.1
1tw4A-5ivaA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 11 GLY A 609
THR A  58
THR A  55
ARG A  86
THR A 162
C8E  A 702 ( 4.0A)
None
None
None
None
1.36A 1utdM-5ivaA:
undetectable
1utdN-5ivaA:
undetectable
1utdM-5ivaA:
8.31
1utdN-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 7 GLY B  72
ASP A 536
ASN A 535
ASP B 111
None
1.02A 2g72B-5ivaB:
undetectable
2g72B-5ivaB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 8 TYR A 194
ASP B 119
TYR A 171
TYR B 108
None
1.39A 2ha2A-5ivaA:
undetectable
2ha2A-5ivaA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 8 TYR A 194
ASP B 119
TYR A 171
TYR B 108
None
1.41A 2ha2B-5ivaA:
undetectable
2ha2B-5ivaA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 GLU A 387
LYS A 393
ILE A 396
LYS A 293
GLU A 274
None
1.42A 2j9dG-5ivaA:
undetectable
2j9dH-5ivaA:
undetectable
2j9dI-5ivaA:
undetectable
2j9dG-5ivaA:
10.36
2j9dH-5ivaA:
10.36
2j9dI-5ivaA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 LYS A 293
GLU A 274
GLU A 387
LYS A 393
ILE A 396
None
1.43A 2j9dG-5ivaA:
undetectable
2j9dH-5ivaA:
undetectable
2j9dI-5ivaA:
undetectable
2j9dG-5ivaA:
10.36
2j9dH-5ivaA:
10.36
2j9dI-5ivaA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 ARG A 270
ASP A 373
ILE B 116
GLU A 231
None
1.29A 2xrzA-5ivaA:
undetectable
2xrzB-5ivaA:
undetectable
2xrzA-5ivaA:
21.84
2xrzB-5ivaA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 6 SER B 118
SER B  69
GLN A 540
ASP B 111
None
1.39A 2zvjA-5ivaB:
undetectable
2zvjA-5ivaB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 GLN A 468
GLN B 103
ASP B 132
ASP A 382
None
1.16A 3bwcB-5ivaA:
undetectable
3bwcB-5ivaA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 GLN A 602
GLN A 158
ASP B 111
THR A 170
None
1.42A 3bwcB-5ivaA:
undetectable
3bwcB-5ivaA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 373
ARG A 207
ARG A 324
None
0.88A 3k37A-5ivaA:
undetectable
3k37A-5ivaA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 11 ASP A  57
SER A  56
PHE A 611
PHE A 572
ASP A 593
None
C8E  A 702 ( 4.9A)
None
None
None
1.44A 3ko0C-5ivaA:
undetectable
3ko0D-5ivaA:
undetectable
3ko0E-5ivaA:
undetectable
3ko0F-5ivaA:
undetectable
3ko0C-5ivaA:
10.61
3ko0D-5ivaA:
10.61
3ko0E-5ivaA:
10.61
3ko0F-5ivaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG202_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 10 ASP A  57
SER A  56
PHE A 611
PHE A 572
ASP A 593
None
C8E  A 702 ( 4.9A)
None
None
None
1.44A 3ko0E-5ivaA:
undetectable
3ko0F-5ivaA:
undetectable
3ko0G-5ivaA:
undetectable
3ko0H-5ivaA:
undetectable
3ko0E-5ivaA:
10.61
3ko0F-5ivaA:
10.61
3ko0G-5ivaA:
10.61
3ko0H-5ivaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 11 PHE A 572
ASP A 593
PHE A 611
ASP A  57
SER A  56
None
None
None
None
C8E  A 702 ( 4.9A)
1.40A 3ko0O-5ivaA:
undetectable
3ko0P-5ivaA:
undetectable
3ko0Q-5ivaA:
undetectable
3ko0R-5ivaA:
undetectable
3ko0O-5ivaA:
10.61
3ko0P-5ivaA:
10.61
3ko0Q-5ivaA:
10.61
3ko0R-5ivaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 11 ASP A 593
PHE A 572
ASP A  57
SER A  56
PHE A 611
None
None
None
C8E  A 702 ( 4.9A)
None
1.48A 3ko0Q-5ivaA:
undetectable
3ko0R-5ivaA:
undetectable
3ko0S-5ivaA:
undetectable
3ko0T-5ivaA:
undetectable
3ko0Q-5ivaA:
10.61
3ko0R-5ivaA:
10.61
3ko0S-5ivaA:
10.61
3ko0T-5ivaA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 ARG B  75
LEU A 164
ILE A 151
PHE A 157
None
1.17A 3ln1D-5ivaB:
undetectable
3ln1D-5ivaB:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 SER A 380
ASP A 480
ASN A 478
None
0.85A 3lsfB-5ivaA:
undetectable
3lsfE-5ivaA:
undetectable
3lsfB-5ivaA:
19.04
3lsfE-5ivaA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 480
ASN A 478
SER A 380
None
0.90A 3lsfB-5ivaA:
undetectable
3lsfE-5ivaA:
undetectable
3lsfB-5ivaA:
19.04
3lsfE-5ivaA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 480
ASN A 478
SER A 492
None
1.02A 3lsfB-5ivaA:
undetectable
3lsfE-5ivaA:
undetectable
3lsfB-5ivaA:
19.04
3lsfE-5ivaA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 480
ASN A 478
SER A 380
None
0.62A 3lslA-5ivaA:
undetectable
3lslD-5ivaA:
undetectable
3lslA-5ivaA:
18.73
3lslD-5ivaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 SER A 380
ASP A 480
ASN A 478
None
0.64A 3lslA-5ivaA:
undetectable
3lslD-5ivaA:
undetectable
3lslA-5ivaA:
18.73
3lslD-5ivaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 10 ASP A  57
SER A  56
PHE A 611
ASP A 593
PHE A 572
None
C8E  A 702 ( 4.9A)
None
None
None
1.37A 3m0wA-5ivaA:
undetectable
3m0wB-5ivaA:
undetectable
3m0wI-5ivaA:
undetectable
3m0wJ-5ivaA:
undetectable
3m0wA-5ivaA:
11.73
3m0wB-5ivaA:
11.73
3m0wI-5ivaA:
11.73
3m0wJ-5ivaA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B203_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 PHE A 611
ASP A  57
SER A  56
PHE A 572
ASP A 593
None
None
C8E  A 702 ( 4.9A)
None
None
1.39A 3m0wA-5ivaA:
undetectable
3m0wB-5ivaA:
undetectable
3m0wC-5ivaA:
undetectable
3m0wD-5ivaA:
undetectable
3m0wA-5ivaA:
11.73
3m0wB-5ivaA:
11.73
3m0wC-5ivaA:
11.73
3m0wD-5ivaA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_D_P77D203_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 10 PHE A 572
ASP A 593
PHE A 611
ASP A  57
SER A  56
None
None
None
None
C8E  A 702 ( 4.9A)
1.41A 3m0wA-5ivaA:
undetectable
3m0wB-5ivaA:
undetectable
3m0wC-5ivaA:
undetectable
3m0wD-5ivaA:
undetectable
3m0wA-5ivaA:
11.73
3m0wB-5ivaA:
11.73
3m0wC-5ivaA:
11.73
3m0wD-5ivaA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 10 ASP A 593
PHE A 572
PHE A 611
ASP A  57
SER A  56
None
None
None
None
C8E  A 702 ( 4.9A)
1.37A 3m0wE-5ivaA:
undetectable
3m0wF-5ivaA:
undetectable
3m0wG-5ivaA:
undetectable
3m0wH-5ivaA:
undetectable
3m0wE-5ivaA:
11.73
3m0wF-5ivaA:
11.73
3m0wG-5ivaA:
11.73
3m0wH-5ivaA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_B_SALB201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 ARG A 389
VAL A 434
VAL A 361
ILE A 396
GLN A 366
None
1.40A 3retB-5ivaA:
undetectable
3retB-5ivaA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 ARG A 349
THR A 351
ASP A 338
GLU A 353
None
1.45A 3v5vC-5ivaA:
undetectable
3v5vD-5ivaA:
undetectable
3v5vC-5ivaA:
20.74
3v5vD-5ivaA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 114
LYS A 113
ASP A 112
None
0.79A 4a7tA-5ivaA:
undetectable
4a7tA-5ivaA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.06A 4coxA-5ivaA:
undetectable
4coxA-5ivaA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.06A 4coxB-5ivaA:
undetectable
4coxB-5ivaA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.06A 4coxD-5ivaA:
undetectable
4coxD-5ivaA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 TYR A 123
ARG A 127
SER A 124
None
1.01A 4dr2I-5ivaA:
undetectable
4dr2J-5ivaA:
undetectable
4dr2I-5ivaA:
12.35
4dr2J-5ivaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 GLU A 353
ARG A 349
THR A 351
ASP A 338
None
1.47A 4e7cA-5ivaA:
undetectable
4e7cB-5ivaA:
undetectable
4e7cA-5ivaA:
20.74
4e7cB-5ivaA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 7 ASP A 536
ASP B 111
ASN B 113
ASP A 523
None
1.04A 4feuB-5ivaA:
undetectable
4feuB-5ivaA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 562
ARG A 567
ASP A 536
None
0.87A 4fp9D-5ivaA:
undetectable
4fp9D-5ivaA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 8 ASP A 206
ASP A 257
ASP A 238
ASP A 122
C8E  A 703 ( 4.1A)
None
None
None
1.05A 4gkhC-5ivaA:
undetectable
4gkhK-5ivaA:
undetectable
4gkhC-5ivaA:
18.32
4gkhK-5ivaA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 8 ASP A 206
ASP A 257
ASP A 238
ASP A 122
C8E  A 703 ( 4.1A)
None
None
None
1.03A 4gkiE-5ivaA:
undetectable
4gkiG-5ivaA:
undetectable
4gkiE-5ivaA:
18.32
4gkiG-5ivaA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 596
ARG A  86
THR A 199
None
0.86A 4i13A-5ivaA:
undetectable
4i13A-5ivaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ARG A 265
ASP A 302
ASP A 269
None
0.92A 4kicB-5ivaA:
undetectable
4kicB-5ivaA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 TYR A 123
ARG A 127
SER A 124
None
1.18A 4lf7I-5ivaA:
undetectable
4lf7J-5ivaA:
undetectable
4lf7I-5ivaA:
12.35
4lf7J-5ivaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 TYR A 123
ARG A 127
SER A 124
None
1.18A 4lf8I-5ivaA:
undetectable
4lf8J-5ivaA:
undetectable
4lf8I-5ivaA:
12.35
4lf8J-5ivaA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 4 ASN B 114
GLY B 117
ASP A 398
ASP A 394
None
1.18A 4n49A-5ivaB:
undetectable
4n49A-5ivaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.09A 4otyA-5ivaA:
undetectable
4otyA-5ivaA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 596
ARG A  86
THR A 199
None
0.87A 4p3rA-5ivaA:
undetectable
4p3rA-5ivaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 8 ASN A 484
PRO A 462
PHE A 379
TYR A 515
None
1.21A 4v30B-5ivaA:
undetectable
4v30B-5ivaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 236
GLY A 268
ASP A 269
None
0.61A 4xdtA-5ivaA:
undetectable
4xdtA-5ivaA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa)
3 / 4 ARG B  75
GLY B  76
GLU B 112
None
0.62A 4z2dB-5ivaB:
undetectable
4z2dC-5ivaB:
undetectable
4z2dB-5ivaB:
18.39
4z2dC-5ivaB:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 214
ARG A 175
ARG A 207
None
0.99A 5eajB-5ivaA:
undetectable
5eajB-5ivaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 ARG A  86
THR A 162
GLY A 609
THR A  58
THR A  55
None
None
C8E  A 702 ( 4.0A)
None
None
1.36A 5eeuL-5ivaA:
undetectable
5eeuV-5ivaA:
undetectable
5eeuL-5ivaA:
8.31
5eeuV-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 ARG A  86
THR A 162
GLY A 609
THR A  58
THR A  55
None
None
C8E  A 702 ( 4.0A)
None
None
1.36A 5eexL-5ivaA:
undetectable
5eexV-5ivaA:
undetectable
5eexL-5ivaA:
8.31
5eexV-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 ARG A  86
THR A 162
GLY A 609
THR A  58
THR A  55
None
None
C8E  A 702 ( 4.0A)
None
None
1.36A 5eeyL-5ivaA:
undetectable
5eeyV-5ivaA:
undetectable
5eeyL-5ivaA:
8.31
5eeyV-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 9 ARG A  86
THR A 162
GLY A 609
THR A  58
THR A  55
None
None
C8E  A 702 ( 4.0A)
None
None
1.37A 5ef0L-5ivaA:
undetectable
5ef0V-5ivaA:
undetectable
5ef0L-5ivaA:
8.31
5ef0V-5ivaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 SER B 118
SER B  69
GLN A 540
ASP B 111
None
1.43A 5fhrB-5ivaB:
undetectable
5fhrB-5ivaB:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.06A 5iktA-5ivaA:
undetectable
5iktA-5ivaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 SER A 408
LEU A 384
VAL A 406
GLY A 424
ALA A 423
None
1.03A 5iktB-5ivaA:
undetectable
5iktB-5ivaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 TYR A 171
TYR B 108
GLN B  65
None
1.01A 5jsdA-5ivaA:
undetectable
5jsdB-5ivaA:
undetectable
5jsdA-5ivaA:
20.40
5jsdB-5ivaA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 TYR A 171
TYR B 108
GLN B  65
None
1.02A 5jsdB-5ivaA:
undetectable
5jsdC-5ivaA:
undetectable
5jsdB-5ivaA:
20.40
5jsdC-5ivaA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
5 / 12 VAL A 594
ASP A 595
SER A 168
THR A 203
ARG A 117
None
1.13A 5m5cB-5ivaA:
undetectable
5m5cB-5ivaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 7 ASN A 484
PRO A 462
PHE A 379
TYR A 515
None
1.27A 5oh1B-5ivaA:
undetectable
5oh1B-5ivaA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
3 / 3 ASP A 201
ASN B 113
ASP A 523
None
0.76A 5vopA-5ivaA:
undetectable
5vopA-5ivaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
5iva LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
3 / 3 ASP A 201
ASN B 113
ASP A 523
None
0.79A 5vopB-5ivaA:
undetectable
5vopB-5ivaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
3 / 3 ASP A 562
ARG A 567
ASP A 536
None
0.88A 5zvgB-5ivaA:
undetectable
5zvgB-5ivaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa)
4 / 6 GLY B  76
THR B  67
GLN B  65
TYR B 108
None
0.79A 6ag0A-5ivaB:
undetectable
6ag0A-5ivaB:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa)
4 / 6 GLY B  76
THR B  67
GLN B  65
TYR B 108
None
0.81A 6ag0C-5ivaB:
undetectable
6ag0C-5ivaB:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Pseudomonas
aeruginosa)
5 / 12 VAL B  90
LEU B  37
LEU B  58
LEU B 137
LEU B 144
None
0.93A 6b0cD-5ivaB:
undetectable
6b0cD-5ivaB:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 THR A 227
ARG B 130
PRO B  32
ARG A 181
None
1.31A 6ew0B-5ivaA:
undetectable
6ew0B-5ivaA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 THR A 227
ARG B 130
PRO B  32
ARG A 181
None
1.31A 6ew0D-5ivaA:
undetectable
6ew0D-5ivaA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 THR A 227
ARG B 130
PRO B  32
ARG A 181
None
1.32A 6ew0H-5ivaA:
undetectable
6ew0H-5ivaA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)
5iva LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa)
4 / 5 THR A 227
ARG B 130
PRO B  32
ARG A 181
None
1.31A 6ew0I-5ivaA:
undetectable
6ew0I-5ivaA:
8.19