SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ivx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		4 / 6 LYS F  12
LEU F  10
GLU F  16
VAL F 116
 None
 1.11A 1sn5A-5ivxF:
undetectable		 1sn5A-5ivxF:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		4 / 8 ASP F  52
SER F  53
SER F  48
GLN F  24
 None
 1.10A 2cmlC-5ivxF:
undetectable		 2cmlC-5ivxF:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		3 / 3 LYS F 128
ARG F 187
VAL F 188
 None
 0.75A 4x3uA-5ivxF:
undetectable
4x3uB-5ivxF:
undetectable		 4x3uA-5ivxF:
15.25
4x3uB-5ivxF:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		4 / 7 SER F 219
ASP F 213
GLY F 208
THR F 108
 None
 0.86A 5btaA-5ivxF:
undetectable
5btaC-5ivxF:
undetectable
5btaD-5ivxF:
undetectable		 5btaA-5ivxF:
16.90
5btaC-5ivxF:
16.90
5btaD-5ivxF:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		4 / 7 SER F 219
ASP F 213
GLY F 208
THR F 108
 None
 0.88A 5btfA-5ivxF:
undetectable
5btfB-5ivxF:
undetectable
5btfC-5ivxF:
undetectable		 5btfA-5ivxF:
16.90
5btfB-5ivxF:
21.29
5btfC-5ivxF:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ivx T-CELL RECEPTOR BETA
CHAIN
(Mus
musculus) 		4 / 7 SER F 219
ASP F 213
GLY F 208
THR F 108
 None
 0.90A 5btfA-5ivxF:
undetectable
5btfC-5ivxF:
undetectable
5btfD-5ivxF:
undetectable		 5btfA-5ivxF:
16.90
5btfC-5ivxF:
16.90
5btfD-5ivxF:
21.29