SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 PHE A 374
PHE A 308
VAL A 333
PHE A 388
ALA A 286
 None
 1.30A 1q23A-5iwzA:
undetectable
1q23B-5iwzA:
undetectable		 1q23A-5iwzA:
20.61
1q23B-5iwzA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 THR A 332
THR A 314
SER A 312
VAL A 210
 None
 1.12A 1tv8A-5iwzA:
undetectable		 1tv8A-5iwzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 THR A 332
THR A 314
SER A 312
VAL A 210
 None
 1.16A 1tv8B-5iwzA:
undetectable		 1tv8B-5iwzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A 288
LEU A 371
LEU A 370
THR A 355
LEU A 356
 None
 1.07A 2egvA-5iwzA:
undetectable		 2egvA-5iwzA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 THR A 332
THR A 314
SER A 312
VAL A 210
 None
 1.16A 2fb2A-5iwzA:
undetectable		 2fb2A-5iwzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 THR A 332
THR A 314
SER A 312
VAL A 210
 None
 1.21A 2fb2B-5iwzA:
undetectable		 2fb2B-5iwzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 4 GLN A 294
GLU A 292
ILE A 295
PRO A 296
 None
 0.89A 2fcnA-5iwzA:
undetectable		 2fcnA-5iwzA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 6 GLN A 294
GLU A 292
ILE A 295
PRO A 296
 None
 1.10A 2fcnA-5iwzA:
undetectable
2fcnB-5iwzA:
undetectable		 2fcnA-5iwzA:
13.30
2fcnB-5iwzA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A  88
ILE A  73
LEU A  70
PHE A 151
VAL A 147
 None
 1.12A 2ygpA-5iwzA:
undetectable		 2ygpA-5iwzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A 354
THR A 355
THR A 381
THR A 384
ILE A 380
 None
 1.17A 3a35A-5iwzA:
undetectable		 3a35A-5iwzA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A 354
THR A 355
THR A 381
THR A 384
ILE A 380
 None
 1.20A 3a35B-5iwzA:
undetectable		 3a35B-5iwzA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A 354
THR A 355
THR A 381
THR A 384
ILE A 380
 None
 1.15A 3a3bA-5iwzA:
undetectable		 3a3bA-5iwzA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.18A 3dqtA-5iwzA:
undetectable
3dqtB-5iwzA:
2.2		 3dqtA-5iwzA:
21.22
3dqtB-5iwzA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.14A 3jx1A-5iwzA:
undetectable
3jx1B-5iwzA:
undetectable		 3jx1A-5iwzA:
22.00
3jx1B-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.24A 3n5tA-5iwzA:
undetectable
3n5tB-5iwzA:
undetectable		 3n5tA-5iwzA:
20.87
3n5tB-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.08A 3n61A-5iwzA:
undetectable
3n61B-5iwzA:
undetectable		 3n61A-5iwzA:
22.00
3n61B-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.09A 3nlrA-5iwzA:
undetectable
3nlrB-5iwzA:
undetectable		 3nlrA-5iwzA:
22.00
3nlrB-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.12A 3nlyA-5iwzA:
undetectable
3nlyB-5iwzA:
undetectable		 3nlyA-5iwzA:
22.00
3nlyB-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_H_LFXH101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 5 SER A 312
GLY A 218
GLU A 258
GLU A 221
 None
 1.15A 3raeB-5iwzA:
undetectable
3raeD-5iwzA:
undetectable		 3raeB-5iwzA:
24.32
3raeD-5iwzA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.10A 3rqlA-5iwzA:
2.0
3rqlB-5iwzA:
undetectable		 3rqlA-5iwzA:
22.00
3rqlB-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.12A 4capA-5iwzA:
undetectable
4capB-5iwzA:
undetectable		 4capA-5iwzA:
22.00
4capB-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.18A 4cx7A-5iwzA:
undetectable
4cx7B-5iwzA:
undetectable		 4cx7A-5iwzA:
20.74
4cx7B-5iwzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.13A 4cx7C-5iwzA:
undetectable
4cx7D-5iwzA:
undetectable		 4cx7C-5iwzA:
20.74
4cx7D-5iwzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.06A 4d32A-5iwzA:
undetectable
4d32B-5iwzA:
undetectable		 4d32A-5iwzA:
22.00
4d32B-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 5 LYS A 174
LEU A 173
GLU A 214
LEU A 215
 None
 1.23A 4k4yA-5iwzA:
2.4		 4k4yA-5iwzA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 4 LYS A 174
LEU A 173
GLU A 214
LEU A 215
 None
 1.26A 4k4yE-5iwzA:
undetectable		 4k4yE-5iwzA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 5 LYS A 174
LEU A 173
GLU A 214
LEU A 215
 None
 1.22A 4k4yI-5iwzA:
2.7		 4k4yI-5iwzA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.22A 4k5jA-5iwzA:
undetectable
4k5jB-5iwzA:
undetectable		 4k5jA-5iwzA:
20.87
4k5jB-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		5 / 12 ILE A 207
LEU A 265
GLY A 211
SER A 312
ASN A 309
 None
 0.98A 4o1eB-5iwzA:
undetectable		 4o1eB-5iwzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 6 LEU A 180
MET A 196
MET A 134
VAL A  97
 None
 1.13A 4okbA-5iwzA:
undetectable		 4okbA-5iwzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.08A 4v3yA-5iwzA:
undetectable
4v3yB-5iwzA:
undetectable		 4v3yA-5iwzA:
22.00
4v3yB-5iwzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.13A 5adlA-5iwzA:
undetectable
5adlB-5iwzA:
undetectable		 5adlA-5iwzA:
20.87
5adlB-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		3 / 3 ASP A 274
ASN A 269
PHE A 308
 None
 0.78A 5dsgB-5iwzA:
undetectable		 5dsgB-5iwzA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.16A 5fj3A-5iwzA:
undetectable
5fj3B-5iwzA:
2.1		 5fj3A-5iwzA:
20.87
5fj3B-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 THR A  65
ILE A  54
LEU A  70
MET A 125
 None
 0.92A 5g48A-5iwzA:
undetectable		 5g48A-5iwzA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.10A 5uo7A-5iwzA:
undetectable
5uo7B-5iwzA:
undetectable		 5uo7A-5iwzA:
22.27
5uo7B-5iwzA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 6 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.17A 5uo8A-5iwzA:
undetectable
5uo8B-5iwzA:
undetectable		 5uo8A-5iwzA:
20.69
5uo8B-5iwzA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.18A 5vv7A-5iwzA:
undetectable
5vv7B-5iwzA:
2.2		 5vv7A-5iwzA:
20.87
5vv7B-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.15A 5vvnA-5iwzA:
undetectable
5vvnB-5iwzA:
undetectable		 5vvnA-5iwzA:
20.87
5vvnB-5iwzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 8 GLU A 258
PHE A 317
SER A 363
LEU A 370
 None
 0.75A 5y2tB-5iwzA:
undetectable		 5y2tB-5iwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 SER A 201
TRP A 239
PHE A 249
GLU A 205
 None
 1.14A 6av6A-5iwzA:
undetectable
6av6B-5iwzA:
undetectable		 6av6A-5iwzA:
10.21
6av6B-5iwzA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2
(Mus
musculus) 		4 / 7 TRP A 239
PHE A 249
GLU A 205
SER A 201
 None
 1.09A 6av6C-5iwzA:
undetectable
6av6D-5iwzA:
undetectable		 6av6C-5iwzA:
10.21
6av6D-5iwzA:
10.21