SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ix1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 PRO A 146
LEU A 135
SER A 131
ILE A 138
SER A 173
 None
 1.15A 1lbcA-5ix1A:
undetectable
1lbcC-5ix1A:
undetectable		 1lbcA-5ix1A:
21.93
1lbcC-5ix1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ILE A 138
SER A 173
PRO A 146
LEU A 135
SER A 131
 None
 1.18A 1lbcA-5ix1A:
undetectable
1lbcC-5ix1A:
undetectable		 1lbcA-5ix1A:
21.93
1lbcC-5ix1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 5 LEU A 422
CYH A 413
ALA A 415
CYH A 416
 None
ZN  A 501 (-2.1A)
ZN  A 501 ( 4.8A)
ZN  A 501 (-2.0A)
 1.13A 1mz9D-5ix1A:
undetectable		 1mz9D-5ix1A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 0.95A 1rxcK-5ix1A:
undetectable		 1rxcK-5ix1A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A  39
ASP A  42
ASP A  67
ASP A  75
THR A 194
 MG  A 503 ( 2.4A)
None
ANP  A 502 (-3.6A)
None
ANP  A 502 (-3.9A)
 1.32A 1s14A-5ix1A:
9.9		 1s14A-5ix1A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 6 ARG A 195
ASP A  53
ILE A 268
GLN A 271
 None
 1.34A 2ya7C-5ix1A:
undetectable		 2ya7C-5ix1A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 11 PRO A 146
LEU A 135
SER A 131
ILE A 138
SER A 173
 None
 1.21A 3h6tA-5ix1A:
undetectable
3h6tC-5ix1A:
undetectable		 3h6tA-5ix1A:
21.93
3h6tC-5ix1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 11 ILE A 138
SER A 173
PRO A 146
LEU A 135
SER A 131
 None
 1.18A 3h6tA-5ix1A:
undetectable
3h6tC-5ix1A:
undetectable		 3h6tA-5ix1A:
21.93
3h6tC-5ix1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 LEU A 170
VAL A 127
GLY A 128
LEU A  77
ILE A 197
 None
 1.12A 3ijdB-5ix1A:
undetectable		 3ijdB-5ix1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A  39
ASP A  42
ASP A  67
ASP A  75
THR A 194
 MG  A 503 ( 2.4A)
None
ANP  A 502 (-3.6A)
None
ANP  A 502 (-3.9A)
 1.04A 3lpsA-5ix1A:
11.9		 3lpsA-5ix1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		3 / 3 GLN A 408
GLU A 451
LYS A 421
 None
 0.94A 3su9A-5ix1A:
undetectable		 3su9A-5ix1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 3uboB-5ix1A:
undetectable		 3uboB-5ix1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 0.99A 4e1vA-5ix1A:
undetectable		 4e1vA-5ix1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 0.97A 4e1vC-5ix1A:
undetectable		 4e1vC-5ix1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 0.99A 4e1vD-5ix1A:
undetectable		 4e1vD-5ix1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 0.97A 4e1vE-5ix1A:
undetectable		 4e1vE-5ix1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		4 / 8 THR A 302
GLY A 304
MET A 316
ILE A 285
 None
 1.00A 4e1vH-5ix1A:
undetectable		 4e1vH-5ix1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4e3aA-5ix1A:
undetectable		 4e3aA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 LEU A  19
MET A  80
LEU A  81
ILE A 198
ILE A 196
 None
ANP  A 502 (-3.1A)
None
None
None
 1.29A 4j26B-5ix1A:
undetectable		 4j26B-5ix1A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4jksA-5ix1A:
undetectable		 4jksA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4jksB-5ix1A:
undetectable		 4jksB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4jkuA-5ix1A:
undetectable		 4jkuA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4jkuB-5ix1A:
undetectable		 4jkuB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k8cA-5ix1A:
undetectable		 4k8cA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4k8cB-5ix1A:
undetectable		 4k8cB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4k8kA-5ix1A:
undetectable		 4k8kA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4k8kB-5ix1A:
undetectable		 4k8kB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4k8pA-5ix1A:
undetectable		 4k8pA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k8pB-5ix1A:
undetectable		 4k8pB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4k8tA-5ix1A:
undetectable		 4k8tA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4k8tB-5ix1A:
undetectable		 4k8tB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k93A-5ix1A:
undetectable		 4k93A-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k93B-5ix1A:
undetectable		 4k93B-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k9cA-5ix1A:
undetectable		 4k9cA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4k9cB-5ix1A:
undetectable		 4k9cB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k9iA-5ix1A:
undetectable		 4k9iA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4k9iB-5ix1A:
undetectable		 4k9iB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4kadA-5ix1A:
undetectable		 4kadA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4kadB-5ix1A:
undetectable		 4kadB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.04A 4kahA-5ix1A:
undetectable		 4kahA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4kahB-5ix1A:
undetectable		 4kahB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4kalA-5ix1A:
undetectable		 4kalA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4kalB-5ix1A:
undetectable		 4kalB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4kanA-5ix1A:
undetectable		 4kanA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4kanB-5ix1A:
undetectable		 4kanB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4kbeA-5ix1A:
undetectable		 4kbeA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4kbeB-5ix1A:
undetectable		 4kbeB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4lbgA-5ix1A:
undetectable		 4lbgA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4lbgB-5ix1A:
undetectable		 4lbgB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4lbxA-5ix1A:
undetectable		 4lbxA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4lbxB-5ix1A:
undetectable		 4lbxB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.03A 4lc4A-5ix1A:
undetectable		 4lc4A-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.02A 4lc4B-5ix1A:
undetectable		 4lc4B-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4lcaA-5ix1A:
undetectable		 4lcaA-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ASN A 121
ASP A  67
GLY A  69
THR A 119
ASP A  44
 None
ANP  A 502 (-3.6A)
None
None
ANP  A 502 (-4.0A)
 1.01A 4lcaB-5ix1A:
undetectable		 4lcaB-5ix1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 9 ARG A 263
TYR A  41
THR A  90
GLY A  93
PRO A  43
 None
 1.46A 4mjrA-5ix1A:
undetectable		 4mjrA-5ix1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 7 ILE A 347
ILE A 315
MET A 317
THR A 370
ILE A 371
 None
 1.46A 5murB-5ix1A:
undetectable		 5murB-5ix1A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 10 ILE A 347
ILE A 315
MET A 317
THR A 370
ILE A 371
 None
 1.41A 5mzrA-5ix1A:
undetectable		 5mzrA-5ix1A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 10 ILE A 347
ILE A 315
MET A 317
THR A 370
ILE A 371
 None
 1.38A 5mzrC-5ix1A:
undetectable		 5mzrC-5ix1A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 9 ILE A 347
ILE A 315
MET A 317
THR A 370
ILE A 371
 None
 1.41A 5mzrD-5ix1A:
undetectable		 5mzrD-5ix1A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 PRO A 423
VAL A 273
PHE A 210
PHE A 212
ILE A 266
 None
 1.44A 6becA-5ix1A:
undetectable
6becB-5ix1A:
undetectable
6becC-5ix1A:
undetectable		 6becA-5ix1A:
20.44
6becB-5ix1A:
20.44
6becC-5ix1A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 VAL A 117
PHE A 104
LEU A 251
MET A 264
GLY A 107
 None
 1.22A 6brdA-5ix1A:
undetectable		 6brdA-5ix1A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5ix1 MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
3
(Mus
musculus) 		5 / 12 ILE A 266
ILE A  52
VAL A 273
ILE A 268
PRO A 245
 None
 1.13A 6hlpA-5ix1A:
undetectable		 6hlpA-5ix1A:
21.38