SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ix3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQJ_A_TRPA650_0
(TRYPTOPHAN
HALOGENASE, PRNA)		 5ix3 DIAMINE
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 PRO A  86
ILE A  82
GLU A  16
PHE A  13
ASN A  18
 None
 1.43A 2aqjA-5ix3A:
1.7		 2aqjA-5ix3A:
14.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ix3 DIAMINE
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 8 GLU A  70
GLU A  79
GLN A  81
ILE A  82
LEU A 116
 None
 0.78A 4mj8A-5ix3A:
23.0		 4mj8A-5ix3A:
54.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 5ix3 DIAMINE
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 ASN A 122
ILE A  84
ILE A  83
GLU A  99
VAL A  56
 None
 1.40A 6hloA-5ix3A:
undetectable		 6hloA-5ix3A:
16.02