SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ixu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 5ixu UNCHARACTERIZED
PROTEIN
(Paraburkholderia
xenovorans) 		3 / 3 TRP A  60
VAL A  98
TRP A  59
 None
 1.35A 1gmkC-5ixuA:
undetectable
1gmkD-5ixuA:
undetectable		 1gmkC-5ixuA:
9.57
1gmkD-5ixuA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 5ixu UNCHARACTERIZED
PROTEIN
(Paraburkholderia
xenovorans) 		5 / 10 LEU A  33
TYR A  28
ILE A  88
PHE A  84
LEU A  75
 None
 0.89A 5y7pB-5ixuA:
undetectable		 5y7pB-5ixuA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 5ixu UNCHARACTERIZED
PROTEIN
(Paraburkholderia
xenovorans) 		5 / 10 LEU A  33
TYR A  28
ILE A  88
PHE A  84
LEU A  75
 None
 0.91A 5y7pD-5ixuA:
undetectable		 5y7pD-5ixuA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 5ixu UNCHARACTERIZED
PROTEIN
(Paraburkholderia
xenovorans) 		5 / 10 LEU A  33
TYR A  28
ILE A  88
PHE A  84
LEU A  75
 None
 0.87A 5y7pH-5ixuA:
undetectable		 5y7pH-5ixuA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5ixu UNCHARACTERIZED
PROTEIN
(Paraburkholderia
xenovorans) 		4 / 5 ARG A  72
ALA A  40
TYR A  39
ILE A  35
 SO4  A 201 (-3.7A)
None
None
None
 1.16A 6g9bA-5ixuA:
undetectable
6g9bB-5ixuA:
undetectable		 6g9bA-5ixuA:
19.66
6g9bB-5ixuA:
17.50