SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iy3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.81A 3k39A-5iy3A:
undetectable		 3k39A-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.80A 3k39C-5iy3A:
undetectable		 3k39C-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.81A 3k39E-5iy3A:
undetectable		 3k39E-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.80A 3k39F-5iy3A:
undetectable		 3k39F-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.81A 3k39G-5iy3A:
undetectable		 3k39G-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.81A 3k39H-5iy3A:
undetectable		 3k39H-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.81A 3k39I-5iy3A:
undetectable		 3k39I-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.80A 3k39J-5iy3A:
undetectable		 3k39J-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.80A 3k39K-5iy3A:
undetectable		 3k39K-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.82A 3k39L-5iy3A:
undetectable		 3k39L-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.82A 3k39M-5iy3A:
undetectable		 3k39M-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		5 / 12 ARG A 211
LEU A 212
ARG A 214
ARG A 276
GLU A 278
 None
 0.80A 3k39O-5iy3A:
undetectable		 3k39O-5iy3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		4 / 6 LEU A 321
ARG A 324
ILE A 275
PHE A 323
 None
 1.07A 5jw1A-5iy3A:
undetectable		 5jw1A-5iy3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		4 / 4 LEU A 321
ARG A 324
ILE A 275
PHE A 323
 None
 1.02A 5kirB-5iy3A:
undetectable		 5kirB-5iy3A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		4 / 6 GLU A 205
LYS A 213
PHE A 277
PRO A 319
 None
 1.16A 6fgdA-5iy3A:
undetectable		 6fgdA-5iy3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5iy3 GENOME POLYPROTEIN
(Zika
virus) 		4 / 7 HIS A 195
THR A 230
HIS A 216
ASP A 197
 None
 1.35A 6mn4E-5iy3A:
undetectable		 6mn4E-5iy3A:
20.35