SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iy5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 11 ALA C 200
ILE C 256
PHE C 198
LEU C 124
PRO C 123
 None
None
PEK  C 303 (-3.8A)
None
None
 1.03A 1dg5A-5iy5C:
undetectable		 1dg5A-5iy5C:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		3 / 3 GLU C 236
HIS C 232
HIS C 148
 NA  C 302 (-3.0A)
NA  C 302 (-3.4A)
NA  C 302 (-3.4A)
 0.46A 1oe2A-5iy5C:
undetectable		 1oe2A-5iy5C:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.31A 1v54C-5iy5C:
37.3
1v54J-5iy5C:
undetectable		 1v54C-5iy5C:
100.00
1v54J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.22A 1v54C-5iy5C:
37.3
1v54J-5iy5C:
undetectable		 1v54C-5iy5C:
100.00
1v54J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		7 / 8 ARG C 156
LYS C 157
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.52A 1v54P-5iy5C:
37.4
1v54W-5iy5C:
undetectable		 1v54P-5iy5C:
100.00
1v54W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.46A 1v55C-5iy5C:
37.3
1v55J-5iy5C:
undetectable		 1v55C-5iy5C:
100.00
1v55J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.28A 1v55C-5iy5C:
37.3
1v55J-5iy5C:
undetectable		 1v55C-5iy5C:
100.00
1v55J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.32A 2dyrC-5iy5C:
37.4
2dyrJ-5iy5C:
undetectable		 2dyrC-5iy5C:
100.00
2dyrJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.25A 2dyrC-5iy5C:
37.4
2dyrJ-5iy5C:
undetectable		 2dyrC-5iy5C:
100.00
2dyrJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		7 / 8 ARG C 156
LYS C 157
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.51A 2dyrP-5iy5C:
37.3
2dyrW-5iy5C:
undetectable		 2dyrP-5iy5C:
100.00
2dyrW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.42A 2dysP-5iy5C:
37.1
2dysW-5iy5C:
undetectable		 2dysP-5iy5C:
100.00
2dysW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.23A 2dysP-5iy5C:
37.1
2dysW-5iy5C:
undetectable		 2dysP-5iy5C:
100.00
2dysW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.38A 2eijC-5iy5C:
37.4
2eijJ-5iy5C:
undetectable		 2eijC-5iy5C:
100.00
2eijJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.25A 2eijC-5iy5C:
37.4
2eijJ-5iy5C:
undetectable		 2eijC-5iy5C:
100.00
2eijJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.44A 2eikC-5iy5C:
37.4
2eikJ-5iy5C:
undetectable		 2eikC-5iy5C:
100.00
2eikJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		7 / 8 ARG C 156
LYS C 157
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.52A 2eikP-5iy5C:
37.3
2eikW-5iy5C:
undetectable		 2eikP-5iy5C:
100.00
2eikW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.41A 2eilC-5iy5C:
37.3
2eilJ-5iy5C:
undetectable		 2eilC-5iy5C:
100.00
2eilJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 8 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.27A 2eilC-5iy5C:
37.3
2eilJ-5iy5C:
undetectable		 2eilC-5iy5C:
100.00
2eilJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.51A 2eimC-5iy5C:
36.9
2eimJ-5iy5C:
undetectable		 2eimC-5iy5C:
100.00
2eimJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.37A 2eimC-5iy5C:
36.9
2eimJ-5iy5C:
undetectable		 2eimC-5iy5C:
100.00
2eimJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.28A 2eimP-5iy5C:
36.8
2eimW-5iy5C:
undetectable		 2eimP-5iy5C:
100.00
2eimW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.48A 2einC-5iy5C:
36.7
2einJ-5iy5C:
undetectable		 2einC-5iy5C:
100.00
2einJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.27A 2einC-5iy5C:
36.7
2einJ-5iy5C:
undetectable		 2einC-5iy5C:
100.00
2einJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.46A 2einP-5iy5C:
36.7
2einW-5iy5C:
undetectable		 2einP-5iy5C:
100.00
2einW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.12A 2y69C-5iy5C:
37.4
2y69J-5iy5C:
undetectable		 2y69C-5iy5C:
100.00
2y69J-5iy5C:
15.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.16A 2y69P-5iy5C:
37.3
2y69W-5iy5C:
undetectable		 2y69P-5iy5C:
100.00
2y69W-5iy5C:
15.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.34A 2zxwP-5iy5C:
37.2
2zxwW-5iy5C:
undetectable		 2zxwP-5iy5C:
100.00
2zxwW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 4 ARG C 156
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.54A 3abkC-5iy5C:
37.4		 3abkC-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.20A 3abkP-5iy5C:
37.3
3abkW-5iy5C:
undetectable		 3abkP-5iy5C:
100.00
3abkW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.25A 3ablC-5iy5C:
37.3
3ablJ-5iy5C:
undetectable		 3ablC-5iy5C:
100.00
3ablJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.33A 3ablP-5iy5C:
37.3
3ablW-5iy5C:
undetectable		 3ablP-5iy5C:
100.00
3ablW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.19A 3abmC-5iy5C:
37.3
3abmJ-5iy5C:
undetectable		 3abmC-5iy5C:
100.00
3abmJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.28A 3abmP-5iy5C:
37.2
3abmW-5iy5C:
undetectable		 3abmP-5iy5C:
100.00
3abmW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LEU C 160
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.25A 3ag1C-5iy5C:
36.5
3ag1J-5iy5C:
undetectable		 3ag1C-5iy5C:
100.00
3ag1J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
PHE C 225
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
None
 0.16A 3ag2C-5iy5C:
37.3		 3ag2C-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
PHE C 225
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
None
 0.48A 3ag2C-5iy5C:
37.3		 3ag2C-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.13A 3ag2P-5iy5C:
37.4
3ag2W-5iy5C:
undetectable		 3ag2P-5iy5C:
100.00
3ag2W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.51A 3ag2P-5iy5C:
37.4
3ag2W-5iy5C:
undetectable		 3ag2P-5iy5C:
100.00
3ag2W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.10A 3ag3C-5iy5C:
37.4
3ag3J-5iy5C:
undetectable		 3ag3C-5iy5C:
100.00
3ag3J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		7 / 8 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
PHE C 225
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
None
 0.38A 3ag4C-5iy5C:
37.3
3ag4J-5iy5C:
undetectable		 3ag4C-5iy5C:
100.00
3ag4J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.00A 3ag4P-5iy5C:
37.3
3ag4W-5iy5C:
undetectable		 3ag4P-5iy5C:
100.00
3ag4W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.45A 3ag4P-5iy5C:
37.3
3ag4W-5iy5C:
undetectable		 3ag4P-5iy5C:
100.00
3ag4W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.40A 3asnC-5iy5C:
37.4
3asnJ-5iy5C:
undetectable		 3asnC-5iy5C:
100.00
3asnJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.34A 3asnP-5iy5C:
37.4
3asnW-5iy5C:
undetectable		 3asnP-5iy5C:
100.00
3asnW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.33A 3asoP-5iy5C:
37.4
3asoW-5iy5C:
undetectable		 3asoP-5iy5C:
100.00
3asoW-5iy5C:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 8 VAL C 248
PHE C  97
HIS C 204
VAL C 245
 UNL  C 308 ( 4.5A)
None
None
None
 1.13A 3fhxB-5iy5C:
undetectable		 3fhxB-5iy5C:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		3 / 3 HIS C 148
HIS C 232
MET C 152
 NA  C 302 (-3.4A)
NA  C 302 (-3.4A)
NA  C 302 ( 3.9A)
 0.83A 3mihA-5iy5C:
undetectable		 3mihA-5iy5C:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.06A 3wg7C-5iy5C:
37.2
3wg7J-5iy5C:
undetectable		 3wg7C-5iy5C:
100.00
3wg7J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.06A 3x2qC-5iy5C:
37.4
3x2qJ-5iy5C:
undetectable		 3x2qC-5iy5C:
100.00
3x2qJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.56A 3x2qC-5iy5C:
37.4
3x2qJ-5iy5C:
undetectable		 3x2qC-5iy5C:
100.00
3x2qJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.19A 3x2qP-5iy5C:
37.4
3x2qW-5iy5C:
undetectable		 3x2qP-5iy5C:
100.00
3x2qW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.54A 3x2qP-5iy5C:
37.4
3x2qW-5iy5C:
undetectable		 3x2qP-5iy5C:
100.00
3x2qW-5iy5C:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 12 ALA C 200
ILE C 256
PHE C 198
LEU C 124
PRO C 123
 None
None
PEK  C 303 (-3.8A)
None
None
 1.02A 4m2xA-5iy5C:
undetectable		 4m2xA-5iy5C:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.14A 5b1bC-5iy5C:
37.4
5b1bJ-5iy5C:
undetectable		 5b1bC-5iy5C:
100.00
5b1bJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.00A 5b1bP-5iy5C:
37.3
5b1bW-5iy5C:
undetectable		 5b1bP-5iy5C:
100.00
5b1bW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.45A 5b1bP-5iy5C:
37.3
5b1bW-5iy5C:
undetectable		 5b1bP-5iy5C:
100.00
5b1bW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.07A 5iy5P-5iy5C:
37.5
5iy5W-5iy5C:
undetectable		 5iy5P-5iy5C:
100.00
5iy5W-5iy5C:
10.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LYS C 157
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.23A 5w97C-5iy5C:
36.6
5w97J-5iy5C:
undetectable		 5w97C-5iy5C:
100.00
5w97J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.11A 5wauC-5iy5C:
37.4
5wauJ-5iy5C:
undetectable		 5wauC-5iy5C:
100.00
5wauJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.12A 5wauc-5iy5C:
37.4
5wauj-5iy5C:
undetectable		 5wauc-5iy5C:
100.00
5wauj-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
None
None
 0.08A 5x19C-5iy5C:
36.5
5x19J-5iy5C:
undetectable		 5x19C-5iy5C:
100.00
5x19J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 6 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.33A 5x19P-5iy5C:
36.5		 5x19P-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		3 / 3 ARG C 156
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
 0.00A 5x1bC-5iy5C:
35.8		 5x1bC-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 5 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.14A 5x1bP-5iy5C:
35.6		 5x1bP-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.22A 5x1fC-5iy5C:
36.7
5x1fJ-5iy5C:
undetectable		 5x1fC-5iy5C:
100.00
5x1fJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		6 / 7 ARG C 156
LYS C 157
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.21A 5x1fP-5iy5C:
36.6
5x1fW-5iy5C:
undetectable		 5x1fP-5iy5C:
100.00
5x1fW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.12A 5xdqC-5iy5C:
37.6
5xdqJ-5iy5C:
undetectable		 5xdqC-5iy5C:
100.00
5xdqJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.00A 5xdqP-5iy5C:
37.5
5xdqW-5iy5C:
undetectable		 5xdqP-5iy5C:
100.00
5xdqW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.00A 5xdxC-5iy5C:
37.5
5xdxJ-5iy5C:
undetectable		 5xdxC-5iy5C:
100.00
5xdxJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
 0.15A 5xdxP-5iy5C:
37.5
5xdxW-5iy5C:
undetectable		 5xdxP-5iy5C:
100.00
5xdxW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.69A 5z84P-5iy5C:
37.5
5z84W-5iy5C:
undetectable		 5z84P-5iy5C:
100.00
5z84W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.13A 5z85C-5iy5C:
37.5
5z85J-5iy5C:
undetectable		 5z85C-5iy5C:
100.00
5z85J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.59A 5z85C-5iy5C:
37.5
5z85J-5iy5C:
undetectable		 5z85C-5iy5C:
100.00
5z85J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.69A 5z85P-5iy5C:
37.5
5z85W-5iy5C:
undetectable		 5z85P-5iy5C:
100.00
5z85W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.63A 5z86C-5iy5C:
37.5
5z86J-5iy5C:
undetectable		 5z86C-5iy5C:
100.00
5z86J-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.68A 5z86P-5iy5C:
37.5
5z86W-5iy5C:
undetectable		 5z86P-5iy5C:
100.00
5z86W-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.07A 5zcoC-5iy5C:
37.5
5zcoJ-5iy5C:
undetectable		 5zcoC-5iy5C:
100.00
5zcoJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.57A 5zcoC-5iy5C:
37.5
5zcoJ-5iy5C:
undetectable		 5zcoC-5iy5C:
100.00
5zcoJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 6 ARG C 156
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
None
 0.16A 5zcoP-5iy5C:
37.5
5zcoW-5iy5C:
undetectable		 5zcoP-5iy5C:
100.00
5zcoW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 6 GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.61A 5zcoP-5iy5C:
37.5
5zcoW-5iy5C:
undetectable		 5zcoP-5iy5C:
100.00
5zcoW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.69A 5zcpC-5iy5C:
37.5
5zcpJ-5iy5C:
undetectable		 5zcpC-5iy5C:
100.00
5zcpJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.70A 5zcpP-5iy5C:
37.4
5zcpW-5iy5C:
undetectable		 5zcpP-5iy5C:
100.00
5zcpW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.13A 5zcqC-5iy5C:
37.5
5zcqJ-5iy5C:
undetectable		 5zcqC-5iy5C:
100.00
5zcqJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.56A 5zcqC-5iy5C:
37.5
5zcqJ-5iy5C:
undetectable		 5zcqC-5iy5C:
100.00
5zcqJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 ARG C 156
LEU C 160
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
None
None
 0.16A 5zcqP-5iy5C:
37.4
5zcqW-5iy5C:
undetectable		 5zcqP-5iy5C:
100.00
5zcqW-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 7 LEU C 160
GLN C 161
PHE C 164
PHE C 219
LEU C 223
 CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
None
 0.60A 5zcqP-5iy5C:
37.4
5zcqW-5iy5C:
undetectable		 5zcqP-5iy5C:
100.00
5zcqW-5iy5C:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 6 SER C 150
ALA C 162
THR C 166
ALA C 239
 None
 1.11A 6ma6A-5iy5C:
undetectable		 6ma6A-5iy5C:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		3 / 3 ARG C 156
LEU C 160
PHE C 164
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-3.9A)
 0.15A 6nknP-5iy5C:
35.8		 6nknP-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMF_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 4 ARG C 156
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.27A 6nmfC-5iy5C:
35.8		 6nmfC-5iy5C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		5 / 6 ARG C 156
LYS C 157
GLN C 161
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
None
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
None
 0.59A 6nmpC-5iy5C:
35.8
6nmpJ-5iy5C:
undetectable		 6nmpC-5iy5C:
100.00
6nmpJ-5iy5C:
10.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3
(Bos
taurus) 		4 / 5 ARG C 156
LEU C 160
GLN C 161
PHE C 164
 CHD  C 307 (-4.0A)
CHD  C 307 ( 3.9A)
CHD  C 307 (-4.3A)
CHD  C 307 (-3.9A)
 0.53A 6nmpP-5iy5C:
35.7
6nmpW-5iy5C:
undetectable		 6nmpP-5iy5C:
100.00
6nmpW-5iy5C:
10.36