SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 12 SER A 340
VAL A 342
GLY A 343
GLY A 212
SER A 263
 None
 1.12A 1fduC-5iz1A:
undetectable		 1fduC-5iz1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 12 THR A 278
GLY A 276
VAL A 267
MET A 259
SER A 289
 None
 0.65A 1jdvE-5iz1A:
undetectable
1jdvF-5iz1A:
undetectable		 1jdvE-5iz1A:
21.75
1jdvF-5iz1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 11 GLY A 276
VAL A 267
MET A 259
SER A 289
ILE A 293
 None
 0.97A 1pk9C-5iz1A:
undetectable		 1pk9C-5iz1A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.47A 1usqB-5iz1A:
undetectable		 1usqB-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.47A 1usqC-5iz1A:
undetectable		 1usqC-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.47A 1usqD-5iz1A:
undetectable		 1usqD-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 9 THR A 278
GLY A 276
VAL A 267
MET A 259
SER A 289
 None
 0.73A 1z37A-5iz1A:
undetectable		 1z37A-5iz1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		4 / 6 ASP A 197
PRO A 181
SER A 156
VAL A 154
 None
 1.20A 2hdnI-5iz1A:
undetectable
2hdnJ-5iz1A:
undetectable
2hdnL-5iz1A:
undetectable		 2hdnI-5iz1A:
7.21
2hdnJ-5iz1A:
21.90
2hdnL-5iz1A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		4 / 6 SER A 156
VAL A 154
ASP A 197
PRO A 181
 None
 1.10A 2hdnJ-5iz1A:
undetectable
2hdnK-5iz1A:
undetectable
2hdnL-5iz1A:
undetectable		 2hdnJ-5iz1A:
21.90
2hdnK-5iz1A:
7.21
2hdnL-5iz1A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.44A 2jkjA-5iz1A:
undetectable		 2jkjA-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.44A 2jkjB-5iz1A:
undetectable		 2jkjB-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.44A 2jkjC-5iz1A:
undetectable		 2jkjC-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 5 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.45A 2jkjD-5iz1A:
undetectable		 2jkjD-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 5 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.44A 2jkjF-5iz1A:
undetectable		 2jkjF-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 6 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.43A 2jklB-5iz1A:
undetectable		 2jklB-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 12 PHE A 196
VAL A 184
PRO A 248
ILE A 217
VAL A 242
 None
 1.11A 3iw1A-5iz1A:
undetectable		 3iw1A-5iz1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 12 TYR A 260
LEU A 199
PRO A 198
GLY A 212
LEU A 126
 None
 1.15A 3okxB-5iz1A:
undetectable		 3okxB-5iz1A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 11 THR A 278
GLY A 276
VAL A 267
SER A 289
ILE A 293
 None
 0.88A 3uawA-5iz1A:
undetectable		 3uawA-5iz1A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 11 THR A 278
VAL A 267
MET A 259
SER A 289
ILE A 293
 None
 0.93A 3uawA-5iz1A:
undetectable		 3uawA-5iz1A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 10 THR A 278
GLY A 276
VAL A 267
MET A 259
ILE A 293
 None
 0.91A 3uayA-5iz1A:
undetectable		 3uayA-5iz1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		3 / 3 LYS A  98
THR A  94
ILE A  89
 None
 0.89A 4e0fB-5iz1A:
undetectable		 4e0fB-5iz1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		4 / 5 ARG A 347
VAL A 342
LEU A 341
SER A 340
 None
 1.18A 4e1gA-5iz1A:
undetectable		 4e1gA-5iz1A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		4 / 7 LEU A 341
ARG A 406
ARG A 369
VAL A 182
 None
 1.24A 4klrA-5iz1A:
undetectable		 4klrA-5iz1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 12 SER A 202
ASP A 197
THR A 180
LEU A 409
MET A 377
 None
 1.15A 4pghB-5iz1A:
undetectable		 4pghB-5iz1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		5 / 11 GLY A 276
VAL A 267
MET A 259
SER A 289
ILE A 293
 None
 0.81A 5i3cC-5iz1A:
undetectable		 5i3cC-5iz1A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		3 / 3 VAL A 195
VAL A 184
GLN A 239
 None
 0.66A 5qgjA-5iz1A:
undetectable		 5qgjA-5iz1A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE
(Physcomitrella
patens) 		3 / 3 ASP A 106
SER A 167
SER A 187
 None
 0.67A 6mxtA-5iz1A:
undetectable		 6mxtA-5iz1A:
21.14