SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		5 / 12 VAL A  38
LEU A  37
PHE A  84
ILE A  32
GLY A   2
 None
 1.25A 3kk6B-5j0fA:
undetectable		 3kk6B-5j0fA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		4 / 5 VAL A 111
LEU A  37
ILE A  56
VAL A  93
 None
 0.91A 4a9kB-5j0fA:
undetectable		 4a9kB-5j0fA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		5 / 10 ALA A  15
VAL A  78
GLY A  80
ILE A  81
VAL A   7
 GOL  A 201 (-4.4A)
None
None
GOL  A 202 ( 4.1A)
None
 0.92A 4j5jB-5j0fA:
undetectable		 4j5jB-5j0fA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		4 / 5 ILE A  82
LEU A  51
HIS A 107
VAL A   7
 None
 1.15A 5jmnB-5j0fA:
undetectable		 5jmnB-5j0fA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		5 / 12 ILE A  56
ALA A  68
ILE A  82
ALA A  70
VAL A  95
 None
 1.06A 5n0tB-5j0fA:
undetectable		 5n0tB-5j0fA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5j0f SUPEROXIDE DISMUTASE
[CU-ZN],OXIDOREDUCTA
SE,SUPEROXIDE
DISMUTASE [CU-ZN]
(Homo
sapiens) 		5 / 12 ILE A  56
GLY A  57
ILE A  58
ILE A  24
ILE A  32
 None
 1.07A 6emuB-5j0fA:
undetectable		 6emuB-5j0fA:
21.88