SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5j0n INTEGRASE
(Escherichia
virus
Lambda) 		5 / 12 GLY E 210
LEU E 331
LEU E 317
SER E 312
ALA E 206
 None
 1.13A 3kkzA-5j0nE:
undetectable		 3kkzA-5j0nE:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 5j0n INTEGRASE
(Escherichia
virus
Lambda) 		5 / 10 LEU E 229
LEU E 216
ILE E 271
THR E 258
THR E 244
 None
 1.26A 3r9cA-5j0nE:
undetectable		 3r9cA-5j0nE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5j0n INTEGRASE
(Escherichia
virus
Lambda) 		4 / 5 SER E 281
THR E 284
GLU E 218
ASP E 223
 None
 1.44A 3tm4B-5j0nE:
undetectable		 3tm4B-5j0nE:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5j0n INTEGRASE
(Escherichia
virus
Lambda) 		3 / 3 LYS E 141
ARG E 176
VAL E 175
 None
 0.77A 4x3uA-5j0nE:
undetectable
4x3uB-5j0nE:
undetectable		 4x3uA-5j0nE:
13.75
4x3uB-5j0nE:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5j0n INTEGRASE
(Escherichia
virus
Lambda) 		3 / 3 TYR E 318
HIS E 247
MET E 255
 None
 1.09A 6af6A-5j0nE:
undetectable		 6af6A-5j0nE:
22.95