SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S79_A_ASDA601_1 (CYTOCHROME P450 19A1)	5j11	THYMIC STROMAL LYMPHOPOIETIN (Homo sapiens)	5 / 12	ILE A 47 TRP A 148 ILE A 39 ALA A 105 LEU A 93	None	1.12A	3s79A-5j11A: undetectable	3s79A-5j11A: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_B_ACTB713_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	5j11	THYMIC STROMAL LYMPHOPOIETIN (Homo sapiens)	3 / 3	GLY A 89 GLN A 140 LYS A 134	None	0.70A	5imsB-5j11A: undetectable	5imsB-5j11A: 13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JKV_A_ASDA602_1 (AROMATASE)	5j11	THYMIC STROMAL LYMPHOPOIETIN (Homo sapiens)	5 / 12	ILE A 47 TRP A 148 ILE A 39 ALA A 105 LEU A 93	None	1.11A	5jkvA-5j11A: undetectable	5jkvA-5j11A: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_A_CCSA14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2)	5j11	THYMIC STROMAL LYMPHOPOIETIN (Homo sapiens)	4 / 6	LEU A 144 TRP A 148 ARG A 150 GLY A 146	None	1.02A	5o4yA-5j11A: undetectable	5o4yA-5j11A: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_F_CCSF14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2)	5j11	THYMIC STROMAL LYMPHOPOIETIN (Homo sapiens)	4 / 6	LEU A 144 TRP A 148 ARG A 150 GLY A 146	None	1.10A	5o4yF-5j11A: undetectable	5o4yF-5j11A: 13.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3S79_A_ASDA601_1","CYTOCHROME P450 19A1","5j11","THYMIC STROMAL LYMPHOPOIETIN","Homo sapiens",5,"ILE A  47;TRP A 148;ILE A  39;ALA A 105;LEU A  93","None","1.12A","3s79A-5j11A:undetectable","3s79A-5j11A:14.16"],["5IMS_B_ACTB713_0","ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL","5j11","THYMIC STROMAL LYMPHOPOIETIN","Homo sapiens",3,"GLY A  89;GLN A 140;LYS A 134","None","0.70A","5imsB-5j11A:undetectable","5imsB-5j11A:13.47"],["5JKV_A_ASDA602_1","AROMATASE","5j11","THYMIC STROMAL LYMPHOPOIETIN","Homo sapiens",5,"ILE A  47;TRP A 148;ILE A  39;ALA A 105;LEU A  93","None","1.11A","5jkvA-5j11A:undetectable","5jkvA-5j11A:14.16"],["5O4Y_A_CCSA14_0","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2","5j11","THYMIC STROMAL LYMPHOPOIETIN","Homo sapiens",4,"LEU A 144;TRP A 148;ARG A 150;GLY A 146","None","1.02A","5o4yA-5j11A:undetectable","5o4yA-5j11A:13.33"],["5O4Y_F_CCSF14_0","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2","5j11","THYMIC STROMAL LYMPHOPOIETIN","Homo sapiens",4,"LEU A 144;TRP A 148;ARG A 150;GLY A 146","None","1.10A","5o4yF-5j11A:undetectable","5o4yF-5j11A:13.33"]]