SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		4 / 6 THR A 174
LEU A 128
VAL A 130
VAL A 136
 None
 1.07A 2zuhA-5j1bA:
undetectable		 2zuhA-5j1bA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.11A 3eeyA-5j1bA:
undetectable		 3eeyA-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.13A 3eeyB-5j1bA:
undetectable		 3eeyB-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.12A 3eeyC-5j1bA:
undetectable		 3eeyC-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.15A 3eeyD-5j1bA:
undetectable		 3eeyD-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.13A 3eeyH-5j1bA:
undetectable		 3eeyH-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 144
ILE A 249
GLY A 250
LEU A 158
THR A 242
 None
 1.09A 3eeyI-5j1bA:
undetectable		 3eeyI-5j1bA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 241
PHE A 159
ILE A 277
VAL A 136
LEU A 285
 None
 1.20A 3eqmA-5j1bA:
undetectable		 3eqmA-5j1bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 264
TYR A 261
ILE A 238
HIS A 248
 None
 1.16A 3eteA-5j1bA:
undetectable
3eteE-5j1bA:
undetectable		 3eteA-5j1bA:
20.65
3eteE-5j1bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 264
TYR A 261
ILE A 238
HIS A 248
 None
 1.15A 3eteB-5j1bA:
undetectable
3eteC-5j1bA:
undetectable		 3eteB-5j1bA:
20.65
3eteC-5j1bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 238
HIS A 248
ILE A 264
TYR A 261
 None
 1.16A 3eteD-5j1bA:
undetectable
3eteF-5j1bA:
undetectable		 3eteD-5j1bA:
20.65
3eteF-5j1bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 241
PHE A 159
ILE A 277
VAL A 136
LEU A 285
 None
 1.22A 3s79A-5j1bA:
undetectable		 3s79A-5j1bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		4 / 8 THR A 174
LEU A 128
VAL A 130
VAL A 136
 None
 1.09A 4l4dA-5j1bA:
undetectable		 4l4dA-5j1bA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 241
PHE A 159
ILE A 277
VAL A 136
LEU A 285
 None
 1.24A 5jkvA-5j1bA:
undetectable		 5jkvA-5j1bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 241
PHE A 159
ILE A 277
VAL A 136
LEU A 285
 None
 1.23A 5jkwA-5j1bA:
undetectable		 5jkwA-5j1bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 241
PHE A 159
ILE A 277
VAL A 136
LEU A 285
 None
 1.23A 5jl7A-5j1bA:
undetectable		 5jl7A-5j1bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5j1b CELL WALL ASSEMBLY
REGULATOR SMI1
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 239
ILE A 238
VAL A 251
VAL A 130
PHE A 140
 None
 1.38A 6j21A-5j1bA:
undetectable		 6j21A-5j1bA:
22.72