SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 11 ALA A 352
ILE A  92
LEU A  65
GLY A 294
ALA A  59
 None
 1.02A 1b02A-5j1dA:
undetectable		 1b02A-5j1dA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 6 ALA A  96
SER A 186
LEU A 339
TRP A 343
 None
 1.22A 1gahA-5j1dA:
undetectable		 1gahA-5j1dA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 9 THR A 205
GLY A 206
GLY A  36
GLU A 147
GLY A   8
 None
 1.30A 1jhoA-5j1dA:
undetectable		 1jhoA-5j1dA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 9 THR A 205
GLY A 206
GLY A  36
GLU A 147
GLY A   8
 None
 1.29A 1jhrA-5j1dA:
undetectable		 1jhrA-5j1dA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 9 THR A 205
GLY A 206
GLY A  36
GLU A 147
GLY A   8
 None
 1.28A 1l5lA-5j1dA:
undetectable		 1l5lA-5j1dA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 GLY A 325
GLY A 315
TYR A 314
ILE A  23
LEU A  11
 None
None
None
None
PO4  A 401 (-4.1A)
 1.07A 1p91B-5j1dA:
undetectable		 1p91B-5j1dA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		3 / 3 LYS A 298
TYR A  86
PRO A 372
 None
 1.08A 2j9cC-5j1dA:
undetectable		 2j9cC-5j1dA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 9 LEU A  11
GLY A 207
GLY A 206
SER A  61
SER A  63
 PO4  A 401 (-4.1A)
None
None
None
None
 1.15A 2qmmA-5j1dA:
undetectable		 2qmmA-5j1dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 THR A  97
ALA A  96
LEU A 339
LEU A 255
PRO A  93
 None
 1.10A 2qxsA-5j1dA:
undetectable		 2qxsA-5j1dA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 THR A  97
ALA A  96
LEU A 339
LEU A 255
PRO A  93
 None
 1.10A 2qxsB-5j1dA:
undetectable		 2qxsB-5j1dA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 10 ILE A 120
ALA A 239
VAL A 142
LEU A 155
PHE A 188
 None
 1.35A 3ay0A-5j1dA:
undetectable		 3ay0A-5j1dA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 LEU A 112
ASP A 111
VAL A 110
GLY A 243
TYR A 283
 None
 1.40A 3hgiA-5j1dA:
undetectable		 3hgiA-5j1dA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 10 SER A 149
VAL A 224
SER A  10
GLY A 206
GLY A 207
 PO4  A 401 (-2.6A)
None
PO4  A 401 (-2.9A)
None
None
 1.45A 3ixlA-5j1dA:
undetectable		 3ixlA-5j1dA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 8 ILE A 140
PHE A 192
PHE A 121
PHE A 188
 None
 0.98A 3ko0B-5j1dA:
undetectable
3ko0J-5j1dA:
undetectable		 3ko0B-5j1dA:
14.48
3ko0J-5j1dA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 8 ILE A 140
PHE A 192
PHE A 121
PHE A 188
 None
 1.01A 3ko0K-5j1dA:
undetectable
3ko0S-5j1dA:
undetectable		 3ko0K-5j1dA:
14.48
3ko0S-5j1dA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 HIS A 334
THR A 289
VAL A  95
ILE A  23
SER A  22
 None
 1.23A 3kpbC-5j1dA:
undetectable		 3kpbC-5j1dA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 6 ALA A 330
ILE A  23
HIS A 313
VAL A  95
 None
 1.17A 3nneG-5j1dA:
undetectable		 3nneG-5j1dA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 ILE A 140
ASN A 198
TYR A 144
VAL A 221
PHE A 188
 None
 1.49A 4a97A-5j1dA:
undetectable
4a97B-5j1dA:
undetectable		 4a97A-5j1dA:
20.66
4a97B-5j1dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 9 ILE A 229
ILE A 101
PHE A 121
PHE A 188
VAL A 224
 None
 1.35A 4afgA-5j1dA:
undetectable
4afgE-5j1dA:
undetectable		 4afgA-5j1dA:
21.47
4afgE-5j1dA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 7 PHE A 291
PHE A  58
PHE A 293
LEU A 310
 None
 0.92A 4ejgC-5j1dA:
undetectable		 4ejgC-5j1dA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 TYR A  16
VAL A 347
LEU A  24
ALA A  59
PHE A 293
 None
 1.41A 4rtbA-5j1dA:
undetectable		 4rtbA-5j1dA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 4 ILE A 140
ASN A 198
ILE A 200
VAL A 143
 None
 1.03A 4uy87-5j1dA:
undetectable		 4uy87-5j1dA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 PHE A 182
PRO A 165
VAL A 168
ALA A 181
 None
 1.20A 4w5oA-5j1dA:
undetectable		 4w5oA-5j1dA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 ALA A  13
THR A 205
GLY A 225
PRO A 226
ALA A 228
 None
 1.19A 4ypmA-5j1dA:
undetectable		 4ypmA-5j1dA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 PHE A 182
PRO A 165
VAL A 168
ALA A 181
 None
 1.16A 4z4cA-5j1dA:
undetectable		 4z4cA-5j1dA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 PHE A 182
PRO A 165
VAL A 168
ALA A 181
 None
 1.19A 4z4dA-5j1dA:
undetectable		 4z4dA-5j1dA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 PHE A 182
PRO A 165
VAL A 168
ALA A 181
 None
 1.17A 4z4eA-5j1dA:
undetectable		 4z4eA-5j1dA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		5 / 12 GLY A 315
TYR A  16
LEU A  24
TYR A  30
THR A 311
 None
 1.01A 5eskA-5j1dA:
undetectable		 5eskA-5j1dA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 PHE A 351
ILE A  92
GLN A 295
ARG A 350
 None
 1.35A 5jm4A-5j1dA:
undetectable		 5jm4A-5j1dA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 4 PHE A 351
ILE A  92
GLN A 295
ARG A 350
 None
 1.17A 5jm4B-5j1dA:
0.8		 5jm4B-5j1dA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 5 GLU A  69
GLY A  36
SER A  63
GLY A 150
 None
None
None
PO4  A 401 (-3.6A)
 1.08A 5kprA-5j1dA:
undetectable		 5kprA-5j1dA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5j1d PHOSPHATE BINDING
PROTEIN
(Stenotrophomonas
maltophilia) 		4 / 8 THR A  37
GLY A  38
GLY A   8
ALA A  31
 None
 0.67A 5vw5A-5j1dA:
undetectable		 5vw5A-5j1dA:
19.84