SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.94A 1wmqA-5j1fA:
undetectable		 1wmqA-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.94A 1wmqB-5j1fA:
undetectable		 1wmqB-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.95A 1wpuA-5j1fA:
undetectable		 1wpuA-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.94A 1wpuB-5j1fA:
2.1		 1wpuB-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.95A 1wrqA-5j1fA:
undetectable		 1wrqA-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.95A 1wrqB-5j1fA:
undetectable		 1wrqB-5j1fA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 GLN A 993
TYR A 992
PHE A 941
LEU A 999
 None
 1.42A 3tgvB-5j1fA:
undetectable		 3tgvB-5j1fA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		3 / 3 GLN A 949
PHE A 941
TYR A 992
 None
 1.01A 3ucjA-5j1fA:
undetectable		 3ucjA-5j1fA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 8 LEU A 909
TRP A 910
LEU A 913
MET A 917
 None
 1.10A 5hs6A-5j1fA:
undetectable		 5hs6A-5j1fA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 6 GLY A 972
ARG A 780
PHE A 963
ARG A 978
 None
 1.18A 5jcnB-5j1fA:
undetectable		 5jcnB-5j1fA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 5j1f PLECTIN,PLECTIN
(Homo
sapiens) 		4 / 4 HIS A 807
VAL A 896
LEU A 811
ALA A 761
 None
 1.23A 6d8pB-5j1fA:
2.1		 6d8pB-5j1fA:
13.86