SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 5j1g PLECTIN
(Homo
sapiens) 		5 / 10 ALA A1072
GLU A1075
LEU A1094
ARG A1091
ILE A1019
 None
 1.46A 1qkuA-5j1gA:
undetectable		 1qkuA-5j1gA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 5j1g PLECTIN
(Homo
sapiens) 		5 / 10 ALA A1072
GLU A1075
LEU A1094
ARG A1091
ILE A1019
 None
 1.46A 1qkuB-5j1gA:
undetectable		 1qkuB-5j1gA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 5j1g PLECTIN
(Homo
sapiens) 		5 / 10 ALA A1072
GLU A1075
LEU A1094
ARG A1091
ILE A1019
 None
 1.47A 1qkuC-5j1gA:
undetectable		 1qkuC-5j1gA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j1g PLECTIN
(Homo
sapiens) 		4 / 6 GLY A1124
ILE A1122
GLN A1126
SER A1119
 None
 0.81A 1rs7B-5j1gA:
undetectable		 1rs7B-5j1gA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5j1g PLECTIN
(Homo
sapiens) 		5 / 12 LEU A1070
ALA A1074
LEU A1090
ILE A1019
LEU A1098
 None
 1.15A 3olsB-5j1gA:
undetectable		 3olsB-5j1gA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j1g PLECTIN
(Homo
sapiens) 		4 / 6 GLY A1124
ILE A1122
GLN A1126
SER A1119
 None
 0.86A 4kcnA-5j1gA:
undetectable		 4kcnA-5j1gA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5j1g PLECTIN
(Homo
sapiens) 		3 / 3 ARG A1069
LEU A1070
GLU A1073
 None
 0.69A 4l3gF-5j1gA:
undetectable		 4l3gF-5j1gA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5j1g PLECTIN
(Homo
sapiens) 		4 / 4 LEU A1101
LEU A1063
GLY A1062
GLU A1061
 None
 1.25A 5hhjA-5j1gA:
undetectable		 5hhjA-5j1gA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5j1g PLECTIN
(Homo
sapiens) 		5 / 12 LEU A1211
GLU A1179
GLY A1124
VAL A1121
THR A1125
 None
 1.17A 5o4yD-5j1gA:
undetectable
5o4yE-5j1gA:
undetectable		 5o4yD-5j1gA:
3.55
5o4yE-5j1gA:
21.43