SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 5j1i PLECTIN
(Homo
sapiens) 		5 / 10 GLU A1075
ALA A1072
LEU A1098
GLU A1095
GLU A1093
 None
 1.18A 1a29A-5j1iA:
undetectable		 1a29A-5j1iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 7 TRP A1249
THR A1354
LEU A1356
LEU A1250
 None
 1.05A 1gtiD-5j1iA:
undetectable		 1gtiD-5j1iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 7 TRP A1249
THR A1354
LEU A1356
LEU A1250
 None
 0.90A 1gtiE-5j1iA:
3.9		 1gtiE-5j1iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 6 GLY A1124
ILE A1122
GLN A1126
SER A1119
 None
 0.85A 1rs7B-5j1iA:
undetectable		 1rs7B-5j1iA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5j1i PLECTIN
(Homo
sapiens) 		3 / 3 THR A1148
PRO A1146
PRO A1150
 None
 0.81A 2d55C-5j1iA:
undetectable		 2d55C-5j1iA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 5 TYR A1302
ARG A1240
THR A1148
LEU A1152
 None
 1.43A 2eimJ-5j1iA:
undetectable		 2eimJ-5j1iA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 5 TYR A1302
ARG A1240
THR A1148
LEU A1152
 None
 1.43A 2eimW-5j1iA:
undetectable		 2eimW-5j1iA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 5 TYR A1302
ARG A1240
THR A1148
LEU A1152
 None
 1.35A 3ag2J-5j1iA:
1.8		 3ag2J-5j1iA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 5 TYR A1302
ARG A1240
THR A1148
LEU A1152
 None
 1.45A 3ag4J-5j1iA:
1.8		 3ag4J-5j1iA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 4 LEU A1152
LEU A1159
GLN A1235
GLU A1310
 None
 1.10A 4i41A-5j1iA:
undetectable		 4i41A-5j1iA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 6 GLY A1124
ILE A1122
GLN A1126
SER A1119
 None
 0.93A 4kcnA-5j1iA:
undetectable		 4kcnA-5j1iA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 4 LEU A1101
LEU A1063
GLY A1062
GLU A1061
 None
 1.25A 5hhjA-5j1iA:
undetectable		 5hhjA-5j1iA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5j1i PLECTIN
(Homo
sapiens) 		5 / 12 LEU A1211
GLU A1179
GLY A1124
VAL A1121
THR A1125
 None
 1.17A 5o4yD-5j1iA:
undetectable
5o4yE-5j1iA:
undetectable		 5o4yD-5j1iA:
2.67
5o4yE-5j1iA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5j1i PLECTIN
(Homo
sapiens) 		4 / 4 TYR A1302
ARG A1240
THR A1148
LEU A1152
 None
 1.33A 5wauj-5j1iA:
1.8		 5wauj-5j1iA:
10.57