SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.10A 1nsiA-5j1qA:
undetectable
1nsiB-5j1qA:
undetectable		 1nsiA-5j1qA:
20.90
1nsiB-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.14A 1nsiA-5j1qA:
undetectable
1nsiB-5j1qA:
undetectable		 1nsiA-5j1qA:
20.90
1nsiB-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.10A 1nsiC-5j1qA:
undetectable
1nsiD-5j1qA:
undetectable		 1nsiC-5j1qA:
20.90
1nsiD-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 ASP A 255
HIS A 196
ASP A  65
 CXA  A 402 (-3.5A)
ZN  A 401 ( 3.2A)
None
 0.71A 1nw5A-5j1qA:
undetectable		 1nw5A-5j1qA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
CXA  A 402 (-3.0A)
 1.26A 2c8aA-5j1qA:
undetectable		 2c8aA-5j1qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		5 / 7 GLY A 278
SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
None
CXA  A 402 (-3.0A)
 1.30A 2c8aB-5j1qA:
undetectable		 2c8aB-5j1qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
CXA  A 402 (-3.0A)
 1.31A 2c8aC-5j1qA:
undetectable		 2c8aC-5j1qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		5 / 11 GLU A 163
GLY A 140
THR A 129
GLY A 167
GLU A 173
 None
 1.44A 2fn1B-5j1qA:
undetectable		 2fn1B-5j1qA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.12A 2nsiA-5j1qA:
undetectable
2nsiB-5j1qA:
undetectable		 2nsiA-5j1qA:
20.90
2nsiB-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.12A 2nsiA-5j1qA:
undetectable
2nsiB-5j1qA:
undetectable		 2nsiA-5j1qA:
20.90
2nsiB-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.12A 2nsiC-5j1qA:
undetectable
2nsiD-5j1qA:
undetectable		 2nsiC-5j1qA:
20.90
2nsiD-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.13A 2nsiC-5j1qA:
undetectable
2nsiD-5j1qA:
undetectable		 2nsiC-5j1qA:
20.90
2nsiD-5j1qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 ILE A 183
ARG A 184
PHE A 147
GLU A 171
 None
 1.13A 2qebB-5j1qA:
undetectable		 2qebB-5j1qA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 CXA  A 402 (-3.0A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 1.9A)
 0.78A 2x45B-5j1qA:
undetectable		 2x45B-5j1qA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 CXA  A 402 (-3.0A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 1.9A)
 0.81A 2x45C-5j1qA:
undetectable		 2x45C-5j1qA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.08A 3e7gA-5j1qA:
undetectable
3e7gB-5j1qA:
undetectable		 3e7gA-5j1qA:
21.28
3e7gB-5j1qA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 8 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.11A 3e7gC-5j1qA:
undetectable
3e7gD-5j1qA:
undetectable		 3e7gC-5j1qA:
21.28
3e7gD-5j1qA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 TYR A  12
GLU A 292
TYR A 234
TYR A 238
 None
 1.27A 3ugrA-5j1qA:
undetectable		 3ugrA-5j1qA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.78A 4fjpA-5j1qA:
undetectable		 4fjpA-5j1qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.83A 4forA-5j1qA:
undetectable		 4forA-5j1qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 TYR A 208
GLN A 261
TRP A 151
 None
 0.96A 4kn2C-5j1qA:
undetectable		 4kn2C-5j1qA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.14A 4nosA-5j1qA:
undetectable
4nosB-5j1qA:
undetectable		 4nosA-5j1qA:
19.95
4nosB-5j1qA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 1.17A 4nosC-5j1qA:
undetectable
4nosD-5j1qA:
undetectable		 4nosC-5j1qA:
19.95
4nosD-5j1qA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		4 / 6 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 1.11A 4nosC-5j1qA:
undetectable
4nosD-5j1qA:
undetectable		 4nosC-5j1qA:
19.95
4nosD-5j1qA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 GLU A 175
ILE A 139
ALA A  70
 None
 0.51A 4wnwB-5j1qA:
undetectable		 4wnwB-5j1qA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		5 / 12 PHE A  78
ILE A 195
LEU A 271
ALA A 296
LEU A 230
 None
 1.12A 5zwrA-5j1qA:
undetectable		 5zwrA-5j1qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		5 / 12 PHE A  78
ILE A 195
LEU A 271
ALA A 296
LEU A 230
 None
 1.09A 5zwrB-5j1qA:
undetectable		 5zwrB-5j1qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 5j1q CARBOXYPEPTIDASE B
(Sus
scrofa) 		3 / 3 HIS A  95
ASN A 302
LEU A 305
 None
 0.84A 6f7lB-5j1qA:
1.4		 6f7lB-5j1qA:
20.96