SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		4 / 8 SER A 151
SER A 193
SER A 191
ASN A 206
 None
 1.11A 2cmlC-5j2sA:
undetectable		 2cmlC-5j2sA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		4 / 5 ASN A 174
LEU A 173
SER A 171
LEU A 131
 None
None
NAG  A 301 (-3.1A)
NAG  A 301 (-3.8A)
 1.27A 4n09C-5j2sA:
undetectable		 4n09C-5j2sA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		5 / 11 ALA A 190
ILE A 154
LEU A 129
LEU A 119
ILE A 113
 None
 1.14A 4xumB-5j2sA:
undetectable		 4xumB-5j2sA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		4 / 4 ASN A 174
LEU A 173
SER A 171
LEU A 131
 None
None
NAG  A 301 (-3.1A)
NAG  A 301 (-3.8A)
 1.35A 5kb5A-5j2sA:
undetectable		 5kb5A-5j2sA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		4 / 7 ASP A 134
GLN A 102
LYS A 104
GLN A 211
 None
 1.41A 6g31A-5j2sA:
undetectable		 6g31A-5j2sA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A
(Rattus
norvegicus) 		4 / 7 ASP A 134
GLN A 102
LYS A 104
GLN A 211
 None
 1.43A 6g31G-5j2sA:
undetectable		 6g31G-5j2sA:
19.58