SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLY A 302
ILE A 301
ALA A 113
ILE A  53
 None
 0.76A 1n49A-5j32A:
undetectable		 1n49A-5j32A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ALA A 337
LEU A 340
ILE A 339
CYH A 386
 None
 0.95A 1sbrA-5j32A:
undetectable
1sbrB-5j32A:
undetectable		 1sbrA-5j32A:
19.85
1sbrB-5j32A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.92A 1v54P-5j32A:
undetectable
1v54W-5j32A:
undetectable		 1v54P-5j32A:
21.50
1v54W-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.99A 1v55C-5j32A:
undetectable
1v55J-5j32A:
undetectable		 1v55C-5j32A:
21.50
1v55J-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASN A 144
LEU A 309
MET A 344
LEU A 345
LEU A 111
 None
 1.29A 1zucB-5j32A:
undetectable		 1zucB-5j32A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.90A 2dyrC-5j32A:
undetectable
2dyrJ-5j32A:
undetectable		 2dyrC-5j32A:
21.50
2dyrJ-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.90A 2dyrP-5j32A:
undetectable
2dyrW-5j32A:
undetectable		 2dyrP-5j32A:
21.50
2dyrW-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.94A 2dysP-5j32A:
undetectable
2dysW-5j32A:
undetectable		 2dysP-5j32A:
21.50
2dysW-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LYS A  62
LEU A  65
GLN A  66
PHE A 317
 None
 1.08A 2dysP-5j32A:
undetectable
2dysW-5j32A:
undetectable		 2dysP-5j32A:
21.50
2dysW-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.99A 2eijC-5j32A:
undetectable
2eijJ-5j32A:
undetectable		 2eijC-5j32A:
21.50
2eijJ-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LYS A  62
LEU A  65
GLN A  66
LEU A 345
 None
 0.92A 2eimC-5j32A:
undetectable
2eimJ-5j32A:
undetectable		 2eimC-5j32A:
21.50
2eimJ-5j32A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 ALA A 333
GLY A 302
ILE A 301
ALA A 113
ILE A  53
 None
 1.04A 2idwA-5j32A:
undetectable		 2idwA-5j32A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ARG A 136
ASP A 292
SER A 291
SER A 306
 IPM  A 502 (-3.0A)
MG  A 501 (-2.9A)
None
None
 0.94A 2j2pD-5j32A:
undetectable
2j2pF-5j32A:
undetectable		 2j2pD-5j32A:
20.30
2j2pF-5j32A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 LEU A  47
ASP A  51
VAL A  57
THR A 338
 None
 1.14A 3cyxB-5j32A:
undetectable		 3cyxB-5j32A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 7 GLN A 134
GLY A  84
GLY A 131
THR A  99
ALA A  87
 None
 1.16A 3fpjB-5j32A:
undetectable		 3fpjB-5j32A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 ALA A 324
ASP A 326
PRO A 335
VAL A  57
ILE A  53
 None
 1.34A 3oxxB-5j32A:
undetectable		 3oxxB-5j32A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A 142
ALA A 216
THR A 219
LEU A 145
 None
 0.80A 3t3sC-5j32A:
undetectable		 3t3sC-5j32A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 GLU A  75
GLY A  73
TYR A  43
GLU A 352
 None
 1.26A 3w9tA-5j32A:
undetectable		 3w9tA-5j32A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 GLU A  75
GLY A  73
TYR A  43
GLU A 352
 None
 1.26A 3w9tC-5j32A:
undetectable		 3w9tC-5j32A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 GLU A  75
GLY A  73
TYR A  43
GLU A 352
 None
 1.26A 3w9tD-5j32A:
undetectable		 3w9tD-5j32A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 GLU A  75
GLY A  73
TYR A  43
GLU A 352
 None
 1.26A 3w9tG-5j32A:
undetectable		 3w9tG-5j32A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A  95
GLY A  85
LYS A 118
ASN A 122
ALA A  86
 None
 1.39A 4pclB-5j32A:
undetectable		 4pclB-5j32A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 VAL A 281
ILE A 376
PRO A 147
THR A 338
 None
 1.29A 4ze1A-5j32A:
undetectable		 4ze1A-5j32A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A  69
GLY A  73
ILE A 359
LYS A 347
LEU A 346
 None
 0.95A 5bw4A-5j32A:
undetectable		 5bw4A-5j32A:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A 181
ILE A 180
LEU A 290
GLY A 287
 IPM  A 502 (-4.5A)
None
None
None
 0.79A 5kmdC-5j32A:
undetectable
5kmdD-5j32A:
undetectable		 5kmdC-5j32A:
22.58
5kmdD-5j32A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLN A 134
LEU A  95
TRP A 119
ALA A  86
 None
 0.90A 5nwvA-5j32A:
undetectable		 5nwvA-5j32A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 390
GLU A 388
GLY A 385
VAL A 384
THR A 373
 None
 1.32A 5o4yD-5j32A:
undetectable
5o4yE-5j32A:
undetectable		 5o4yD-5j32A:
4.27
5o4yE-5j32A:
16.75