SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		4 / 5 SER A 386
PHE A 164
VAL A 323
PHE A 324
 None
 1.49A 1oipA-5j3uA:
undetectable		 1oipA-5j3uA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		4 / 4 VAL A 371
LEU A 398
ILE A 362
LEU A 361
 None
 0.99A 2byoA-5j3uA:
undetectable		 2byoA-5j3uA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		4 / 6 PHE A 324
LEU A 282
VAL A 285
VAL A 394
 None
 1.05A 2zuhA-5j3uA:
undetectable		 2zuhA-5j3uA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		4 / 6 PHE A 324
LEU A 282
VAL A 285
VAL A 394
 None
 0.99A 4ek1A-5j3uA:
undetectable		 4ek1A-5j3uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		5 / 12 ILE A 326
GLY A 353
VAL A 285
HIS A 286
ILE A 287
 None
 0.87A 4rvdA-5j3uA:
undetectable		 4rvdA-5j3uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		5 / 12 ILE A 326
GLY A 353
VAL A 285
HIS A 286
ILE A 287
 None
 0.90A 4rvgA-5j3uA:
undetectable		 4rvgA-5j3uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		3 / 3 ASP A 230
GLU A 383
SER A 251
 None
 0.85A 5bw4B-5j3uA:
undetectable		 5bw4B-5j3uA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5j3u PROTEIN KINASE A
(Toxoplasma
gondii) 		5 / 12 LEU A 160
ASP A 170
ASN A 175
ALA A 180
VAL A 267
 None
 1.23A 5kbwB-5j3uA:
undetectable		 5kbwB-5j3uA:
23.02