SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j46'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		5 / 11 CYH A 106
SER A 108
LEU A  21
HIS A 152
LEU A  45
 ZN  A 200 (-2.3A)
None
None
ZN  A 200 (-3.3A)
None
 1.39A 1ee2A-5j46A:
undetectable		 1ee2A-5j46A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		5 / 11 CYH A 106
SER A 108
LEU A  21
HIS A 152
LEU A  45
 ZN  A 200 (-2.3A)
None
None
ZN  A 200 (-3.3A)
None
 1.41A 1ee2B-5j46A:
undetectable		 1ee2B-5j46A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		3 / 3 ASP A  39
ARG A  41
ASP A  36
 None
 0.55A 1vptA-5j46A:
undetectable		 1vptA-5j46A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		4 / 6 VAL A 144
LEU A 141
ILE A 146
CYH A 145
 None
 0.84A 4asdA-5j46A:
undetectable		 4asdA-5j46A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		3 / 3 ASP A  39
ARG A  41
ASP A  36
 None
 0.63A 4fp9D-5j46A:
undetectable		 4fp9D-5j46A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		3 / 3 ASP A  39
ARG A  41
ASP A  36
 None
 0.56A 4fzvA-5j46A:
undetectable		 4fzvA-5j46A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		4 / 5 GLN A 147
HIS A 148
ILE A 146
ILE A  73
 None
ZN  A 200 (-3.3A)
None
None
 1.15A 5dnuA-5j46A:
undetectable		 5dnuA-5j46A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		4 / 5 GLN A 147
HIS A 148
ILE A 146
ILE A  73
 None
ZN  A 200 (-3.3A)
None
None
 1.07A 5dnvA-5j46A:
undetectable		 5dnvA-5j46A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		3 / 3 ASP A  39
ARG A  41
ASP A  36
 None
 0.67A 5zvgA-5j46A:
undetectable		 5zvgA-5j46A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5j46 PEPTIDE DEFORMYLASE
(Burkholderia
multivorans) 		3 / 3 ASP A  39
ARG A  41
ASP A  36
 None
 0.63A 5zvgB-5j46A:
undetectable		 5zvgB-5j46A:
17.31