SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		5 / 12 VAL A 534
VAL A 527
LEU A 424
GLY A 491
LEU A 538
 None
 0.99A 1eqhB-5j47A:
undetectable		 1eqhB-5j47A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 8 ARG A 555
GLY A 432
THR A 435
GLN A 571
 6JJ  A 703 (-3.3A)
6JJ  A 703 ( 4.1A)
6JJ  A 703 (-3.7A)
None
 0.79A 1jr1B-5j47A:
undetectable		 1jr1B-5j47A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 6 LEU A 289
PHE A 328
ILE A 337
ALA A 341
 None
 0.74A 2j5mA-5j47A:
undetectable		 2j5mA-5j47A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 6 LEU A 370
LEU A 369
TRP A 600
ILE A 597
 None
 0.94A 2rlfB-5j47A:
undetectable
2rlfC-5j47A:
undetectable		 2rlfB-5j47A:
7.53
2rlfC-5j47A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 GLU A 319
HIS A 317
HIS A 314
 None
None
ZN  A 701 (-3.3A)
 0.72A 3co4A-5j47A:
undetectable		 3co4A-5j47A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 THR A 434
LYS A 372
GLU A 474
 None
 1.00A 3ijdB-5j47A:
undetectable		 3ijdB-5j47A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 GLY A 391
TRP A 394
VAL A 620
 None
 0.72A 3n62B-5j47A:
undetectable		 3n62B-5j47A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 GLY A 391
TRP A 394
VAL A 620
 None
 0.72A 3n65B-5j47A:
undetectable		 3n65B-5j47A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 GLY A 391
TRP A 394
VAL A 620
 None
 0.73A 3n66B-5j47A:
undetectable		 3n66B-5j47A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 ALA A 383
VAL A 384
GLN A 387
 None
 0.67A 3of4B-5j47A:
undetectable		 3of4B-5j47A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 5 ASP A 628
LEU A 627
ILE A 608
PHE A 613
 None
 1.23A 3s3vA-5j47A:
undetectable		 3s3vA-5j47A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 4 LEU A 462
GLY A 463
LEU A 510
GLU A 511
 None
 1.04A 3tgvB-5j47A:
undetectable		 3tgvB-5j47A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 5 LEU A 410
GLU A 408
MET A 402
LEU A 579
 None
 1.26A 4xi3B-5j47A:
undetectable		 4xi3B-5j47A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 8 THR A 575
LEU A 443
ILE A 406
LEU A 440
 None
 0.92A 5g48A-5j47A:
undetectable		 5g48A-5j47A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		4 / 8 LEU A 627
LEU A 385
THR A 575
GLN A 571
 None
 1.16A 5hbsA-5j47A:
undetectable		 5hbsA-5j47A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		3 / 3 GLY A 391
TRP A 394
VAL A 620
 None
 0.71A 5vuoB-5j47A:
undetectable		 5vuoB-5j47A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 5j47 LARGE T ANTIGEN
(Human
polyomavirus
2) 		5 / 12 PHE A 377
ARG A 596
PHE A 315
GLY A 378
GLY A 381
 None
 1.06A 6brdB-5j47A:
undetectable		 6brdB-5j47A:
11.65