SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 8 PHE A  59
ALA A  44
HIS A  42
LEU A  94
 None
 1.18A 1x8vA-5j4fA:
undetectable		 1x8vA-5j4fA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 10 ILE A  74
PHE A  59
LEU A  84
HIS A  82
HIS A  42
 None
 1.28A 3o1cA-5j4fA:
undetectable		 3o1cA-5j4fA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 10 ILE A  74
PHE A  59
LEU A  84
HIS A  82
HIS A  42
 None
 1.28A 3o1xA-5j4fA:
undetectable		 3o1xA-5j4fA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 10 ILE A  74
PHE A  59
LEU A  84
HIS A  82
HIS A  42
 None
 1.28A 3qgzA-5j4fA:
undetectable		 3qgzA-5j4fA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A  59
ILE A  57
PHE A  12
ILE A  48
 None
 0.70A 6b5vA-5j4fA:
undetectable
6b5vC-5j4fA:
undetectable		 6b5vA-5j4fA:
17.50
6b5vC-5j4fA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A  59
ILE A  57
PHE A  12
ILE A  48
 None
 0.70A 6b5vC-5j4fA:
undetectable
6b5vD-5j4fA:
undetectable		 6b5vC-5j4fA:
17.50
6b5vD-5j4fA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5j4f UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A  59
ILE A  57
PHE A  12
ILE A  48
 None
 0.71A 6b5vB-5j4fA:
undetectable
6b5vD-5j4fA:
undetectable		 6b5vB-5j4fA:
17.50
6b5vD-5j4fA:
17.50