SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j4o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 5j4o SPECTRIN ALPHA
CHAIN, ERYTHROCYTIC
1
(Homo
sapiens) 		4 / 6 LYS A  50
GLN A  52
LEU A  54
GLU A  55
 None
 0.88A 3h5gA-5j4oA:
undetectable
3h5gC-5j4oA:
undetectable		 3h5gA-5j4oA:
9.96
3h5gC-5j4oA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5j4o SPECTRIN ALPHA
CHAIN, ERYTHROCYTIC
1
(Homo
sapiens) 		5 / 12 LEU A  65
LEU A  68
ASN A  69
LEU A  71
ALA A  72
 None
 0.72A 4fn9A-5j4oA:
undetectable		 4fn9A-5j4oA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5j4o SPECTRIN ALPHA
CHAIN, ERYTHROCYTIC
1
(Homo
sapiens) 		4 / 7 ASP A 142
LEU A 217
GLN A 225
LEU A 224
 None
 1.13A 4ib4A-5j4oA:
undetectable		 4ib4A-5j4oA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5j4o SPECTRIN ALPHA
CHAIN, ERYTHROCYTIC
1
(Homo
sapiens) 		4 / 5 TYR A 115
SER A  43
ALA A  42
GLN A 122
 None
None
None
EDO  A 304 (-3.8A)
 1.39A 5n0wB-5j4oA:
undetectable		 5n0wB-5j4oA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5j4o SPECTRIN ALPHA
CHAIN, ERYTHROCYTIC
1
(Homo
sapiens) 		4 / 5 TYR A 115
SER A  43
ALA A  42
GLN A 122
 None
None
None
EDO  A 304 (-3.8A)
 1.38A 5n4iA-5j4oA:
undetectable		 5n4iA-5j4oA:
21.43