SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 6 PHE A  16
ARG A  19
PRO A  56
GLU A  67
SER A  68
 GSH  A 301 (-3.9A)
None
GSH  A 301 (-4.4A)
GSH  A 301 (-3.2A)
GSH  A 301 (-2.7A)
 0.31A 3vlnA-5j4uA:
24.2		 3vlnA-5j4uA:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		3 / 3 SER A  82
ALA A  83
THR A 150
 None
 0.76A 5n0xB-5j4uA:
undetectable		 5n0xB-5j4uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 5 GLN A 192
ARG A 189
TYR A 145
ASP A 202
 None
 1.34A 5yf0A-5j4uA:
1.1		 5yf0A-5j4uA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 7 TYR A  74
HIS A  60
LEU A  24
VAL A  29
 None
 1.21A 6g2pA-5j4uA:
undetectable		 6g2pA-5j4uA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 7 TYR A 186
LEU A 191
TYR A 145
VAL A 196
 None
 1.34A 6g2pA-5j4uA:
undetectable		 6g2pA-5j4uA:
20.09