SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 PHE A 473
HIS A 476
HIS A 167
HIS A 284
 None
FE  A 501 ( 3.1A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
 0.97A 1bzmA-5j55A:
undetectable		 1bzmA-5j55A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 7 VAL A 438
LEU A  26
VAL A  75
LEU A 471
 None
 0.87A 1cqpA-5j55A:
undetectable
1cqpB-5j55A:
undetectable		 1cqpA-5j55A:
18.86
1cqpB-5j55A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.06A 1p6kA-5j55A:
undetectable		 1p6kA-5j55A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.03A 1p6kB-5j55A:
undetectable		 1p6kB-5j55A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.10A 1rs6A-5j55A:
undetectable		 1rs6A-5j55A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 11 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.29A 1ydbA-5j55A:
undetectable		 1ydbA-5j55A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.35A 1yddA-5j55A:
undetectable		 1yddA-5j55A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.06A 1zzqA-5j55A:
undetectable		 1zzqA-5j55A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.01A 1zzqB-5j55A:
undetectable		 1zzqB-5j55A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.02A 1zzuB-5j55A:
undetectable		 1zzuB-5j55A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 7 THR A 118
ALA A 183
TYR A 214
LEU A 187
 None
 1.05A 2hzqA-5j55A:
undetectable		 2hzqA-5j55A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APT_B_ACTB311_0
(METHYLENETETRAHYDROF
OLATE REDUCTASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 9 HIS A  69
LEU A 487
ALA A 145
ILE A 485
TYR A  41
 None
 1.42A 3aptB-5j55A:
undetectable		 3aptB-5j55A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 12 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.30A 3bl1A-5j55A:
undetectable		 3bl1A-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.31A 3cajA-5j55A:
undetectable		 3cajA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
LEU A 475
THR A 121
PRO A  45
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
V55  A 503 ( 3.3A)
V55  A 503 ( 3.3A)
V55  A 503 ( 4.8A)
 1.31A 3cajA-5j55A:
undetectable		 3cajA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.34A 3dazA-5j55A:
undetectable		 3dazA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.31A 3dcsA-5j55A:
undetectable		 3dcsA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 THR A 253
ASP A 312
GLU A 322
 None
 0.85A 3qowA-5j55A:
undetectable		 3qowA-5j55A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 HIS A 476
HIS A 218
HIS A 284
 FE  A 501 ( 3.1A)
FE  A 501 (-3.2A)
FE  A 501 ( 3.3A)
 0.58A 3qpkB-5j55A:
undetectable		 3qpkB-5j55A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 11 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.33A 3v2jA-5j55A:
undetectable		 3v2jA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 10 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.32A 3v2mA-5j55A:
undetectable		 3v2mA-5j55A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 HIS A 284
GLU A 418
ASN A 122
 FE  A 501 ( 3.3A)
None
None
 1.01A 4bupB-5j55A:
undetectable		 4bupB-5j55A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 391
ASP A 375
ARG A 378
TRP A 409
 None
 1.36A 4cpzA-5j55A:
5.8		 4cpzA-5j55A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 THR A 118
GLY A  63
VAL A  43
PRO A  45
 None
None
None
V55  A 503 ( 4.8A)
 1.08A 4grkA-5j55A:
undetectable		 4grkA-5j55A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 12 GLN A 417
GLY A 477
ALA A 123
PHE A  40
THR A  66
 None
 1.21A 4hytA-5j55A:
undetectable		 4hytA-5j55A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 12 GLN A 417
GLY A 477
ALA A 123
PHE A  40
THR A  66
 None
 1.20A 4hytC-5j55A:
undetectable		 4hytC-5j55A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 LEU A 391
ASP A 375
ARG A 378
TRP A 409
 None
 1.31A 4mwrA-5j55A:
5.8		 4mwrA-5j55A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 4 ASN A 287
GLY A 363
ASP A 427
ASP A 359
 None
 1.23A 4n49A-5j55A:
undetectable		 4n49A-5j55A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 PHE A 248
PHE A 310
LEU A 475
PRO A  45
 None
None
V55  A 503 ( 3.3A)
V55  A 503 ( 4.8A)
 1.34A 4o8zA-5j55A:
undetectable		 4o8zA-5j55A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 SER A 234
GLU A 135
LYS A 134
ASN A  60
 None
V55  A 503 ( 3.3A)
V55  A 503 (-2.7A)
None
 1.46A 4pclA-5j55A:
undetectable		 4pclA-5j55A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 9 HIS A 218
HIS A 167
HIS A 284
PHE A 310
THR A 121
 FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
FE  A 501 ( 3.3A)
None
V55  A 503 ( 3.3A)
 1.29A 4pxxA-5j55A:
undetectable		 4pxxA-5j55A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 THR A 253
ASP A 312
GLU A 322
 None
 0.72A 5fa8A-5j55A:
undetectable		 5fa8A-5j55A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_A_URFA301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 4 ARG A  78
ASP A  22
HIS A  69
ARG A  67
 None
 1.34A 5iaoA-5j55A:
0.0		 5iaoA-5j55A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 7 PHE A 309
SER A   9
ASP A  56
ASN A 103
 None
 0.99A 5n5dA-5j55A:
undetectable		 5n5dA-5j55A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.07A 5vunB-5j55A:
undetectable		 5vunB-5j55A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.09A 5vuoB-5j55A:
undetectable		 5vuoB-5j55A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 HIS A 284
GLU A 418
ASN A 122
 FE  A 501 ( 3.3A)
None
None
 1.02A 5wbvB-5j55A:
undetectable		 5wbvB-5j55A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 12 LEU A 140
PRO A 138
ALA A 139
ASP A 136
PHE A  59
 None
None
None
None
V55  A 503 (-3.4A)
 1.22A 5x6yC-5j55A:
undetectable		 5x6yC-5j55A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 5 HIS A 284
HIS A 476
HIS A 167
HIS A 218
 FE  A 501 ( 3.3A)
FE  A 501 ( 3.1A)
FE  A 501 (-3.3A)
FE  A 501 (-3.2A)
 0.95A 5zrdB-5j55A:
undetectable		 5zrdB-5j55A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 4 HIS A 284
HIS A 476
HIS A 167
HIS A 218
 FE  A 501 ( 3.3A)
FE  A 501 ( 3.1A)
FE  A 501 (-3.3A)
FE  A 501 (-3.2A)
 0.94A 5zrdC-5j55A:
undetectable		 5zrdC-5j55A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 4 HIS A 284
HIS A 476
HIS A 167
HIS A 218
 FE  A 501 ( 3.3A)
FE  A 501 ( 3.1A)
FE  A 501 (-3.3A)
FE  A 501 (-3.2A)
 0.93A 5zrdD-5j55A:
undetectable		 5zrdD-5j55A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.10A 6auuB-5j55A:
undetectable		 6auuB-5j55A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 LEU A 390
ASN A  14
LEU A 442
 None
 0.50A 6exiD-5j55A:
undetectable		 6exiD-5j55A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 LEU A 475
ASN A 440
LEU A 372
 V55  A 503 ( 3.3A)
None
None
 0.68A 6exiD-5j55A:
undetectable		 6exiD-5j55A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5j55 CAROTENOID OXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 HIS A 284
HIS A 218
HIS A 167
 FE  A 501 ( 3.3A)
FE  A 501 (-3.2A)
FE  A 501 (-3.3A)
 0.72A 6giqa-5j55A:
undetectable		 6giqa-5j55A:
22.06