SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		6 / 12 VAL B   2
ALA B  24
ARG B  76
ASN B  81
VAL B  83
ALA B 102
 None
 0.90A 3qxtA-5j56B:
21.3		 3qxtA-5j56B:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		7 / 12 VAL B   2
LEU B   4
ALA B  24
ARG B  76
VAL B  83
ALA B 102
TYR B 117
 None
 0.81A 3qxtB-5j56B:
21.3		 3qxtB-5j56B:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		6 / 12 ALA B  24
ARG B  76
ASN B  78
VAL B  83
ALA B 102
TYR B 117
 None
 0.91A 3qxvA-5j56B:
20.6		 3qxvA-5j56B:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		6 / 12 VAL B   2
ALA B  24
ARG B  76
ASN B  78
VAL B  83
TYR B 117
 None
 1.18A 3qxvA-5j56B:
20.6		 3qxvA-5j56B:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		5 / 12 ALA B  24
ARG B  76
VAL B  83
ALA B 102
TYR B 117
 None
 0.67A 3qxvB-5j56B:
20.5		 3qxvB-5j56B:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		6 / 12 VAL B   2
ALA B  24
ARG B  76
VAL B  83
ALA B 102
TYR B 117
 None
 0.91A 3qxvD-5j56B:
20.7		 3qxvD-5j56B:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		6 / 12 CYH B  22
ALA B  24
ARG B  76
VAL B  83
ALA B 102
TYR B 117
 None
 0.68A 3qxvE-5j56B:
17.5		 3qxvE-5j56B:
67.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		4 / 5 ALA B 108
SER B  53
GLY B  38
TYR B 115
 None
 1.27A 5yodD-5j56B:
undetectable		 5yodD-5j56B:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		3 / 3 TYR B  64
GLY B  70
THR B  73
 None
 0.16A 6cjkB-5j56B:
18.1		 6cjkB-5j56B:
53.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5j56 VHH SINGLE CHAIN
ANTIBODY V1C7
(Vicugna
pacos) 		3 / 3 ASP B 116
SER B 111
SER B 109
 None
 0.58A 6mxtA-5j56B:
undetectable		 6mxtA-5j56B:
16.43