SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5j5l UNCHARACTERIZED
PROTEIN
(Aspergillus
fumigatus) 		4 / 8 LEU A  55
VAL A 123
GLY A 122
GLN A 117
 None
 0.75A 2wd9B-5j5lA:
undetectable		 2wd9B-5j5lA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5j5l UNCHARACTERIZED
PROTEIN
(Aspergillus
fumigatus) 		5 / 12 ALA A 133
GLU A  69
LEU A  68
GLN A  67
VAL A 127
 None
None
None
None
ACD  A 201 (-4.1A)
 1.02A 3ix9A-5j5lA:
undetectable		 3ix9A-5j5lA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5j5l UNCHARACTERIZED
PROTEIN
(Aspergillus
fumigatus) 		5 / 12 LEU A 128
LEU A 131
ASN A 132
LEU A 134
ALA A 167
 None
ACD  A 201 ( 4.6A)
None
ACD  A 201 (-4.2A)
None
 1.09A 4fn9A-5j5lA:
undetectable		 4fn9A-5j5lA:
22.39