SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AJ6_A_NOVA1_1 (GYRASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	5 / 9	ASN A 51 ASP A 78 ARG A 140 ILE A 98 THR A 172	MG A 503 ( 2.5A) ANP A 501 (-2.6A) None ANP A 501 ( 3.4A) ANP A 501 (-3.5A)	1.45A	1aj6A-5j5pA: 27.9	1aj6A-5j5pA: 32.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AJ6_A_NOVA1_1 (GYRASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	7 / 9	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 THR A 172	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.5A)	0.73A	1aj6A-5j5pA: 27.9	1aj6A-5j5pA: 32.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KIJ_A_NOVA400_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 12	ASP A 54 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 ARG A 140 THR A 172	None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) None ANP A 501 (-3.5A)	0.62A	1kijA-5j5pA: 45.6	1kijA-5j5pA: 46.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KIJ_B_NOVB444_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 12	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 ARG A 140 THR A 172	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) None ANP A 501 (-3.5A)	0.71A	1kijB-5j5pA: 46.0	1kijB-5j5pA: 46.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S14_A_NOVA1300_1 (TOPOISOMERASE IV SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	10 / 12	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ILE A 98 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None ANP A 501 ( 3.4A) None ANP A 501 (-3.5A)	0.56A	1s14A-5j5pA: 24.8	1s14A-5j5pA: 26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S14_B_NOVB2300_1 (TOPOISOMERASE IV SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 12	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ILE A 98 ARG A 140	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None ANP A 501 ( 3.4A) None	0.55A	1s14B-5j5pA: 26.8	1s14B-5j5pA: 26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_A_NFZA1219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 8	TYR A 263 ASN A 264 LYS A 239 GLY A 323	None	1.04A	1ykiA-5j5pA: undetectable 1ykiB-5j5pA: undetectable	1ykiA-5j5pA: 19.90 1ykiB-5j5pA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_C_NFZC3219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 8	TYR A 263 ASN A 264 LYS A 239 GLY A 323	None	1.05A	1ykiC-5j5pA: undetectable 1ykiD-5j5pA: undetectable	1ykiC-5j5pA: 19.90 1ykiD-5j5pA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_D_NFZD4219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 8	TYR A 263 ASN A 264 LYS A 239 GLY A 323	None	1.03A	1ykiC-5j5pA: undetectable 1ykiD-5j5pA: undetectable	1ykiC-5j5pA: 19.90 1ykiD-5j5pA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZGY_A_BRLA503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 5	ILE A 101 ILE A 138 MET A 90 LEU A 134	None	0.83A	1zgyA-5j5pA: undetectable	1zgyA-5j5pA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_C_KLNC1499_1 (CYTOCHROME P450 3A4)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PHE A 339 LEU A 57 ILE A 64 GLY A 117	None	0.95A	2v0mC-5j5pA: undetectable	2v0mC-5j5pA: 23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BC9_A_ACRA901_1 (ALPHA AMYLASE, CATALYTIC REGION)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	ASP A 37 SER A 35 GLU A 47 ASP A 50	None None ANP A 501 (-4.4A) None	1.26A	3bc9A-5j5pA: undetectable	3bc9A-5j5pA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLD_B_GW6B2_2 (GLUCOCORTICOID RECEPTOR)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 8	LEU A 290 ALA A 325 LEU A 324 ILE A 330	None	0.91A	3cldB-5j5pA: undetectable	3cldB-5j5pA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GV1_B_BEZB303_0 (DISULFIDE INTERCHANGE PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 4	LEU A 44 ALA A 129 VAL A 25 PRO A 29	None	1.14A	3gv1B-5j5pA: undetectable	3gv1B-5j5pA: 17.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LPS_A_NOVA901_1 (TOPOISOMERASE IV SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	10 / 12	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ILE A 98 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None ANP A 501 ( 3.4A) None ANP A 501 (-3.5A)	0.58A	3lpsA-5j5pA: 39.0	3lpsA-5j5pA: 36.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_A_PFLA319_1 (GLR4197 PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PRO A 155 ILE A 92 THR A 100 ILE A 101	None	0.92A	3p50A-5j5pA: undetectable	3p50A-5j5pA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_B_PFLB319_1 (GLR4197 PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PRO A 155 ILE A 92 THR A 100 ILE A 101	None	0.93A	3p50B-5j5pA: undetectable	3p50B-5j5pA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_C_PFLC319_1 (GLR4197 PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PRO A 155 ILE A 92 THR A 100 ILE A 101	None	0.93A	3p50C-5j5pA: undetectable	3p50C-5j5pA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_D_PFLD320_1 (GLR4197 PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PRO A 155 ILE A 92 THR A 100 ILE A 101	None	0.91A	3p50D-5j5pA: undetectable	3p50D-5j5pA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_E_PFLE319_1 (GLR4197 PROTEIN)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	PRO A 155 ILE A 92 THR A 100 ILE A 101	None	0.96A	3p50E-5j5pA: undetectable	3p50E-5j5pA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE506_1 (HEMOLYTIC LECTIN CEL-III)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 6	THR A 115 ASN A 276 GLY A 117 ASP A 54	None	1.35A	3w9tE-5j5pA: undetectable	3w9tE-5j5pA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F93_B_SANB3004_1 (U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 8	GLU A 55 GLU A 334 GLN A 110 GLY A 111	ANP A 501 (-3.2A) None None None	0.93A	4f93B-5j5pA: undetectable	4f93B-5j5pA: 12.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_A_NOVA2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None None ANP A 501 (-3.5A)	0.92A	4urnA-5j5pA: 30.3	4urnA-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_A_NOVA2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.5A)	1.11A	4urnA-5j5pA: 30.3	4urnA-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_B_NOVB2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None None ANP A 501 (-3.5A)	0.82A	4urnB-5j5pA: 27.7	4urnB-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_B_NOVB2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 ARG A 140	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) None	0.99A	4urnB-5j5pA: 27.7	4urnB-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_C_NOVC2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 MET A 83 PRO A 84 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None ANP A 501 (-4.7A) None None ANP A 501 (-3.5A)	0.83A	4urnC-5j5pA: 30.2	4urnC-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URN_C_NOVC2000_1 (DNA TOPOISOMERASE IV, B SUBUNIT)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 11	ASN A 51 ASP A 54 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 ARG A 140 THR A 172	MG A 503 ( 2.5A) None ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) None ANP A 501 (-3.5A)	0.92A	4urnC-5j5pA: 30.2	4urnC-5j5pA: 40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URO_A_NOVA2000_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 12	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 SER A 124 ARG A 140	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.2A) None	0.76A	4uroA-5j5pA: 28.7	4uroA-5j5pA: 40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URO_B_NOVB2000_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 12	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 SER A 124 ARG A 140	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.2A) None	0.87A	4uroB-5j5pA: 28.5	4uroB-5j5pA: 40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URO_C_NOVC2000_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	8 / 12	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 SER A 124 ARG A 140	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.2A) None	0.78A	4uroC-5j5pA: 28.8	4uroC-5j5pA: 40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URO_D_NOVD2000_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	6 / 12	ASN A 51 ASP A 78 ARG A 140 ILE A 98 SER A 124 THR A 172	MG A 503 ( 2.5A) ANP A 501 (-2.6A) None ANP A 501 ( 3.4A) ANP A 501 (-3.2A) ANP A 501 (-3.5A)	1.43A	4uroD-5j5pA: 28.4	4uroD-5j5pA: 40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4URO_D_NOVD2000_1 (DNA GYRASE SUBUNIT B)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	9 / 12	ASN A 51 GLU A 55 ASP A 78 ARG A 81 PRO A 84 ILE A 98 SER A 124 ARG A 140 THR A 172	MG A 503 ( 2.5A) ANP A 501 (-3.2A) ANP A 501 (-2.6A) None None ANP A 501 ( 3.4A) ANP A 501 (-3.2A) None ANP A 501 (-3.5A)	0.76A	4uroD-5j5pA: 28.4	4uroD-5j5pA: 40.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 6	GLY A 123 SER A 125 VAL A 126 HIS A 103	ANP A 501 (-3.4A) NA A 502 (-3.0A) None None	1.02A	5ewuA-5j5pA: undetectable	5ewuA-5j5pA: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_B_BEZB1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 6	GLY A 123 SER A 125 VAL A 126 HIS A 103	ANP A 501 (-3.4A) NA A 502 (-3.0A) None None	1.06A	5ewuB-5j5pA: undetectable	5ewuB-5j5pA: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MA7_A_TPFA602_0 (CYTOCHROME P450 3A4)	5j5p	DNA TOPOISOMERASE 4 SUBUNIT B (Streptococcus pneumoniae)	4 / 7	ARG A 386 ALA A 388 ILE A 383 ALA A 382	None	0.97A	6ma7A-5j5pA: undetectable	6ma7A-5j5pA: 13.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AJ6_A_NOVA1_1","GYRASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",5,"ASN A  51;ASP A  78;ARG A 140;ILE A  98;THR A 172"," MG A 503 ( 2.5A);ANP A 501 (-2.6A);None;ANP A 501 ( 3.4A);ANP A 501 (-3.5A)","1.45A","1aj6A-5j5pA:27.9","1aj6A-5j5pA:32.76"],["1AJ6_A_NOVA1_1","GYRASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",7,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;THR A 172"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.5A)","0.73A","1aj6A-5j5pA:27.9","1aj6A-5j5pA:32.76"],["1KIJ_A_NOVA400_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASP A  54;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;ARG A 140;THR A 172","None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);None;ANP A 501 (-3.5A)","0.62A","1kijA-5j5pA:45.6","1kijA-5j5pA:46.53"],["1KIJ_B_NOVB444_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;ARG A 140;THR A 172"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);None;ANP A 501 (-3.5A)","0.71A","1kijB-5j5pA:46.0","1kijB-5j5pA:46.53"],["1S14_A_NOVA1300_1","TOPOISOMERASE IV SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",10,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ILE A  98;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;ANP A 501 ( 3.4A);None;ANP A 501 (-3.5A)","0.56A","1s14A-5j5pA:24.8","1s14A-5j5pA:26.85"],["1S14_B_NOVB2300_1","TOPOISOMERASE IV SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ILE A  98;ARG A 140"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;ANP A 501 ( 3.4A);None","0.55A","1s14B-5j5pA:26.8","1s14B-5j5pA:26.85"],["1YKI_A_NFZA1219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"TYR A 263;ASN A 264;LYS A 239;GLY A 323","None","1.04A","1ykiA-5j5pA:undetectable;1ykiB-5j5pA:undetectable","1ykiA-5j5pA:19.90;1ykiB-5j5pA:19.90"],["1YKI_C_NFZC3219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"TYR A 263;ASN A 264;LYS A 239;GLY A 323","None","1.05A","1ykiC-5j5pA:undetectable;1ykiD-5j5pA:undetectable","1ykiC-5j5pA:19.90;1ykiD-5j5pA:19.90"],["1YKI_D_NFZD4219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"TYR A 263;ASN A 264;LYS A 239;GLY A 323","None","1.03A","1ykiC-5j5pA:undetectable;1ykiD-5j5pA:undetectable","1ykiC-5j5pA:19.90;1ykiD-5j5pA:19.90"],["1ZGY_A_BRLA503_2","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"ILE A 101;ILE A 138;MET A  90;LEU A 134","None","0.83A","1zgyA-5j5pA:undetectable","1zgyA-5j5pA:19.95"],["2V0M_C_KLNC1499_1","CYTOCHROME P450 3A4","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PHE A 339;LEU A  57;ILE A  64;GLY A 117","None","0.95A","2v0mC-5j5pA:undetectable","2v0mC-5j5pA:23.03"],["3BC9_A_ACRA901_1","ALPHA AMYLASE, CATALYTIC REGION","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"ASP A  37;SER A  35;GLU A  47;ASP A  50","None;None;ANP A 501 (-4.4A);None","1.26A","3bc9A-5j5pA:undetectable","3bc9A-5j5pA:22.34"],["3CLD_B_GW6B2_2","GLUCOCORTICOID RECEPTOR","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"LEU A 290;ALA A 325;LEU A 324;ILE A 330","None","0.91A","3cldB-5j5pA:undetectable","3cldB-5j5pA:19.81"],["3GV1_B_BEZB303_0","DISULFIDE INTERCHANGE PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"LEU A  44;ALA A 129;VAL A  25;PRO A  29","None","1.14A","3gv1B-5j5pA:undetectable","3gv1B-5j5pA:17.11"],["3LPS_A_NOVA901_1","TOPOISOMERASE IV SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",10,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ILE A  98;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;ANP A 501 ( 3.4A);None;ANP A 501 (-3.5A)","0.58A","3lpsA-5j5pA:39.0","3lpsA-5j5pA:36.12"],["3P50_A_PFLA319_1","GLR4197 PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PRO A 155;ILE A  92;THR A 100;ILE A 101","None","0.92A","3p50A-5j5pA:undetectable","3p50A-5j5pA:21.79"],["3P50_B_PFLB319_1","GLR4197 PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PRO A 155;ILE A  92;THR A 100;ILE A 101","None","0.93A","3p50B-5j5pA:undetectable","3p50B-5j5pA:21.79"],["3P50_C_PFLC319_1","GLR4197 PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PRO A 155;ILE A  92;THR A 100;ILE A 101","None","0.93A","3p50C-5j5pA:undetectable","3p50C-5j5pA:21.79"],["3P50_D_PFLD320_1","GLR4197 PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PRO A 155;ILE A  92;THR A 100;ILE A 101","None","0.91A","3p50D-5j5pA:undetectable","3p50D-5j5pA:21.79"],["3P50_E_PFLE319_1","GLR4197 PROTEIN","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"PRO A 155;ILE A  92;THR A 100;ILE A 101","None","0.96A","3p50E-5j5pA:undetectable","3p50E-5j5pA:21.79"],["3W9T_E_W9TE506_1","HEMOLYTIC LECTIN CEL-III","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"THR A 115;ASN A 276;GLY A 117;ASP A  54","None","1.35A","3w9tE-5j5pA:undetectable","3w9tE-5j5pA:20.87"],["4F93_B_SANB3004_1","U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"GLU A  55;GLU A 334;GLN A 110;GLY A 111","ANP A 501 (-3.2A);None;None;None","0.93A","4f93B-5j5pA:undetectable","4f93B-5j5pA:12.80"],["4URN_A_NOVA2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;None;ANP A 501 (-3.5A)","0.92A","4urnA-5j5pA:30.3","4urnA-5j5pA:40.00"],["4URN_A_NOVA2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.5A)","1.11A","4urnA-5j5pA:30.3","4urnA-5j5pA:40.00"],["4URN_B_NOVB2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;None;ANP A 501 (-3.5A)","0.82A","4urnB-5j5pA:27.7","4urnB-5j5pA:40.00"],["4URN_B_NOVB2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;ARG A 140"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);None","0.99A","4urnB-5j5pA:27.7","4urnB-5j5pA:40.00"],["4URN_C_NOVC2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;MET A  83;PRO A  84;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;ANP A 501 (-4.7A);None;None;ANP A 501 (-3.5A)","0.83A","4urnC-5j5pA:30.2","4urnC-5j5pA:40.00"],["4URN_C_NOVC2000_1","DNA TOPOISOMERASE IV, B SUBUNIT","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;ASP A  54;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;ARG A 140;THR A 172"," MG A 503 ( 2.5A);None;ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);None;ANP A 501 (-3.5A)","0.92A","4urnC-5j5pA:30.2","4urnC-5j5pA:40.00"],["4URO_A_NOVA2000_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;SER A 124;ARG A 140"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.2A);None","0.76A","4uroA-5j5pA:28.7","4uroA-5j5pA:40.18"],["4URO_B_NOVB2000_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;SER A 124;ARG A 140"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.2A);None","0.87A","4uroB-5j5pA:28.5","4uroB-5j5pA:40.18"],["4URO_C_NOVC2000_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",8,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;SER A 124;ARG A 140"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.2A);None","0.78A","4uroC-5j5pA:28.8","4uroC-5j5pA:40.18"],["4URO_D_NOVD2000_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",6,"ASN A  51;ASP A  78;ARG A 140;ILE A  98;SER A 124;THR A 172"," MG A 503 ( 2.5A);ANP A 501 (-2.6A);None;ANP A 501 ( 3.4A);ANP A 501 (-3.2A);ANP A 501 (-3.5A)","1.43A","4uroD-5j5pA:28.4","4uroD-5j5pA:40.18"],["4URO_D_NOVD2000_1","DNA GYRASE SUBUNIT B","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",9,"ASN A  51;GLU A  55;ASP A  78;ARG A  81;PRO A  84;ILE A  98;SER A 124;ARG A 140;THR A 172"," MG A 503 ( 2.5A);ANP A 501 (-3.2A);ANP A 501 (-2.6A);None;None;ANP A 501 ( 3.4A);ANP A 501 (-3.2A);None;ANP A 501 (-3.5A)","0.76A","4uroD-5j5pA:28.4","4uroD-5j5pA:40.18"],["5EWU_A_BEZA1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"GLY A 123;SER A 125;VAL A 126;HIS A 103","ANP A 501 (-3.4A); NA A 502 (-3.0A);None;None","1.02A","5ewuA-5j5pA:undetectable","5ewuA-5j5pA:24.18"],["5EWU_B_BEZB1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"GLY A 123;SER A 125;VAL A 126;HIS A 103","ANP A 501 (-3.4A); NA A 502 (-3.0A);None;None","1.06A","5ewuB-5j5pA:undetectable","5ewuB-5j5pA:24.18"],["6MA7_A_TPFA602_0","CYTOCHROME P450 3A4","5j5p","DNA TOPOISOMERASE 4 SUBUNIT B","Streptococcus pneumoniae",4,"ARG A 386;ALA A 388;ILE A 383;ALA A 382","None","0.97A","6ma7A-5j5pA:undetectable","6ma7A-5j5pA:13.07"]]