SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 0.94A 1fm6A-5j5vC:
undetectable		 1fm6A-5j5vC:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 1.06A 1xdkE-5j5vC:
undetectable		 1xdkE-5j5vC:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 0.95A 1xiuA-5j5vC:
undetectable		 1xiuA-5j5vC:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 1.05A 1xiuB-5j5vC:
undetectable		 1xiuB-5j5vC:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		4 / 7 ILE C   8
GLY C   9
ARG C   5
PHE C  27
 None
 0.67A 2vctD-5j5vC:
3.4		 2vctD-5j5vC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5j5v TRNA NUCLEASE CDIA
(Escherichia
coli) 		4 / 8 ASN B 191
THR B 195
LEU B 196
ALA B 211
 None
 1.04A 3kp6A-5j5vB:
undetectable		 3kp6A-5j5vB:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5j5v IMMUNITY PROTEIN
CDII
TRNA NUCLEASE CDIA
(Escherichia
coli) 		4 / 6 GLY C  76
ASN B 184
GLU C  77
GLN B 136
 None
 1.11A 4g0vB-5j5vC:
undetectable		 4g0vB-5j5vC:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5j5v TRNA NUCLEASE CDIA
(Escherichia
coli) 		5 / 11 LEU B 160
ILE B 218
SER B 220
MET B 182
LEU B 186
 None
 1.42A 4lhmA-5j5vB:
undetectable		 4lhmA-5j5vB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C 100
VAL C  60
LEU C  43
LEU C  64
ALA C  81
 None
 1.17A 4m11D-5j5vC:
undetectable		 4m11D-5j5vC:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 11 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 0.93A 4nqaA-5j5vC:
undetectable		 4nqaA-5j5vC:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 10 ILE C  53
LEU C  56
VAL C  63
LEU C  64
LEU C  90
 None
 1.18A 5ienB-5j5vC:
undetectable		 5ienB-5j5vC:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 9 LEU C  56
ILE C  30
GLU C  41
VAL C  40
GLU C  36
 None
 1.42A 5igzA-5j5vC:
undetectable		 5igzA-5j5vC:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 0.92A 6a5yD-5j5vC:
undetectable		 6a5yD-5j5vC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5j5v IMMUNITY PROTEIN
CDII
(Escherichia
coli) 		5 / 12 ILE C  30
ALA C  46
GLN C  49
PHE C  27
LEU C  35
 None
 0.95A 6a60D-5j5vC:
undetectable		 6a60D-5j5vC:
20.00