SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5j6y ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 5 ASP A 111
SER A 130
ASP A  60
GLN A  27
 BGC  A 310 ( 2.5A)
BGC  A 310 ( 4.8A)
None
CA  A 302 (-3.2A)
 1.03A 1n2xB-5j6yA:
undetectable		 1n2xB-5j6yA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5j6y ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 4 GLU A  48
GLY A  19
THR A  46
GLU A  20
 None
None
None
CA  A 306 ( 4.9A)
 1.03A 3e9xA-5j6yA:
undetectable		 3e9xA-5j6yA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5j6y ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 PHE A 162
VAL A 107
PHE A 105
ILE A 117
 None
 0.78A 3zjqA-5j6yA:
undetectable		 3zjqA-5j6yA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5j6y ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 VAL A 125
VAL A 161
PHE A 162
ILE A 115
 None
 0.88A 3zjqA-5j6yA:
undetectable		 3zjqA-5j6yA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 5j6y ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 PHE A 162
VAL A 107
PHE A 105
ILE A 117
 None
 0.82A 3zjqB-5j6yA:
undetectable		 3zjqB-5j6yA:
24.45