SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA502_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5j7m	CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN (Kribbella flavida)	3 / 3	ASP A 49 HIS A 51 HIS A 89	NI A 202 (-3.2A) NI A 202 ( 3.5A) NI A 202 ( 3.7A)	0.67A	1oe1A-5j7mA: undetectable	1oe1A-5j7mA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA502_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5j7m	CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN (Kribbella flavida)	3 / 3	ASP A 49 HIS A 51 HIS A 89	NI A 202 (-3.2A) NI A 202 ( 3.5A) NI A 202 ( 3.7A)	0.66A	1oe3A-5j7mA: undetectable	1oe3A-5j7mA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q64_B_1UNB1001_2 (PROTEASE RETROPEPSIN)	5j7m	CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN (Kribbella flavida)	3 / 3	ARG A 94 THR A 71 VAL A 72	None	0.94A	2q64A-5j7mA: undetectable	2q64A-5j7mA: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5j7m	CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN (Kribbella flavida)	3 / 3	ASP A 49 HIS A 51 HIS A 89	NI A 202 (-3.2A) NI A 202 ( 3.5A) NI A 202 ( 3.7A)	0.69A	2xxgA-5j7mA: undetectable	2xxgA-5j7mA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1339_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5j7m	CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN (Kribbella flavida)	3 / 3	ASP A 49 HIS A 51 HIS A 89	NI A 202 (-3.2A) NI A 202 ( 3.5A) NI A 202 ( 3.7A)	0.67A	2xxgC-5j7mA: undetectable	2xxgC-5j7mA: 19.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA502_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5j7m","CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN","Kribbella flavida",3,"ASP A  49;HIS A  51;HIS A  89"," NI A 202 (-3.2A); NI A 202 ( 3.5A); NI A 202 ( 3.7A)","0.67A","1oe1A-5j7mA:undetectable","1oe1A-5j7mA:19.58"],["1OE3_A_CUA502_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5j7m","CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN","Kribbella flavida",3,"ASP A  49;HIS A  51;HIS A  89"," NI A 202 (-3.2A); NI A 202 ( 3.5A); NI A 202 ( 3.7A)","0.66A","1oe3A-5j7mA:undetectable","1oe3A-5j7mA:19.58"],["2Q64_B_1UNB1001_2","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","5j7m","CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN","Kribbella flavida",3,"ARG A  94;THR A  71;VAL A  72","None","0.94A","2q64A-5j7mA:undetectable","2q64A-5j7mA:19.71"],["2XXG_A_CUA1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5j7m","CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN","Kribbella flavida",3,"ASP A  49;HIS A  51;HIS A  89"," NI A 202 (-3.2A); NI A 202 ( 3.5A); NI A 202 ( 3.7A)","0.69A","2xxgA-5j7mA:undetectable","2xxgA-5j7mA:19.58"],["2XXG_C_CUC1339_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5j7m","CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN","Kribbella flavida",3,"ASP A  49;HIS A  51;HIS A  89"," NI A 202 (-3.2A); NI A 202 ( 3.5A); NI A 202 ( 3.7A)","0.67A","2xxgC-5j7mA:undetectable","2xxgC-5j7mA:19.58"]]