SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HXW_B_RITB301_1 (HIV-1 PROTEASE)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	5 / 9	ASP A 119 ASP A 117 GLY A 77 ILE A 78 ILE A 134	None	1.04A	1hxwA-5j7nA: undetectable	1hxwA-5j7nA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG1_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	3 / 3	TRP A 43 VAL A 44 PRO A 45	None	1.00A	1rg1A-5j7nA: undetectable	1rg1A-5j7nA: 16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RH0_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	3 / 3	TRP A 43 VAL A 44 PRO A 45	None	0.99A	1rh0A-5j7nA: undetectable	1rh0A-5j7nA: 16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HS2_A_017A201_2 (PROTEASE)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	5 / 12	ASP A 119 ASP A 117 GLY A 77 ILE A 78 ILE A 134	None	0.99A	2hs2B-5j7nA: undetectable	2hs2B-5j7nA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TTP_A_017A201_1 (HIV-1 PROTEASE)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	6 / 10	ASP A 119 ASP A 117 GLY A 77 ILE A 78 LEU A 58 ILE A 134	None	1.32A	3ttpA-5j7nA: undetectable	3ttpA-5j7nA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TTP_A_017A201_2 (HIV-1 PROTEASE)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	6 / 10	ASP A 119 ASP A 117 GLY A 77 ILE A 78 LEU A 58 ILE A 134	None	1.31A	3ttpB-5j7nA: undetectable	3ttpB-5j7nA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJV_A_RITA500_2 (PROTEASE)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	5 / 11	ASP A 119 ASP A 117 GLY A 77 ILE A 78 ILE A 134	None	0.97A	4njvB-5j7nA: undetectable	4njvB-5j7nA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQY_B_017B101_1 (PROTEASE E35D-DRV)	5j7n	LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN (Xylella fastidiosa)	5 / 12	LEU A 58 ASP A 117 GLY A 77 ILE A 78 ILE A 134	None	1.09A	5kqyA-5j7nA: undetectable	5kqyA-5j7nA: 22.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HXW_B_RITB301_1","HIV-1 PROTEASE;HIV-1 PROTEASE","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",5,"ASP A 119;ASP A 117;GLY A  77;ILE A  78;ILE A 134","None","1.04A","1hxwA-5j7nA:undetectable","1hxwA-5j7nA:22.50"],["1RG1_A_SPMA999_1","TYROSYL-DNA PHOSPHODIESTERASE 1","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",3,"TRP A  43;VAL A  44;PRO A  45","None","1.00A","1rg1A-5j7nA:undetectable","1rg1A-5j7nA:16.22"],["1RH0_A_SPMA999_1","TYROSYL-DNA PHOSPHODIESTERASE 1","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",3,"TRP A  43;VAL A  44;PRO A  45","None","0.99A","1rh0A-5j7nA:undetectable","1rh0A-5j7nA:16.22"],["2HS2_A_017A201_2","PROTEASE;PROTEASE","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",5,"ASP A 119;ASP A 117;GLY A  77;ILE A  78;ILE A 134","None","0.99A","2hs2B-5j7nA:undetectable","2hs2B-5j7nA:23.12"],["3TTP_A_017A201_1","HIV-1 PROTEASE","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",6,"ASP A 119;ASP A 117;GLY A  77;ILE A  78;LEU A  58;ILE A 134","None","1.32A","3ttpA-5j7nA:undetectable","3ttpA-5j7nA:21.25"],["3TTP_A_017A201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",6,"ASP A 119;ASP A 117;GLY A  77;ILE A  78;LEU A  58;ILE A 134","None","1.31A","3ttpB-5j7nA:undetectable","3ttpB-5j7nA:21.25"],["4NJV_A_RITA500_2","PROTEASE;PROTEASE","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",5,"ASP A 119;ASP A 117;GLY A  77;ILE A  78;ILE A 134","None","0.97A","4njvB-5j7nA:undetectable","4njvB-5j7nA:20.62"],["5KQY_B_017B101_1","PROTEASE E35D-DRV;PROTEASE E35D-DRV","5j7n","LOW MOLECULAR WEIGHT HEAT SHOCK PROTEIN","Xylella fastidiosa",5,"LEU A  58;ASP A 117;GLY A  77;ILE A  78;ILE A 134","None","1.09A","5kqyA-5j7nA:undetectable","5kqyA-5j7nA:22.22"]]