SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 7 GLN A 880
TYR A 878
PHE A 839
PHE A 809
 None
 0.97A 1e71M-5j7tA:
undetectable		 1e71M-5j7tA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 7 GLN A 880
TYR A 878
PHE A 839
PHE A 809
 None
 1.01A 1e72M-5j7tA:
undetectable		 1e72M-5j7tA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 6 GLN A 880
TYR A 878
PHE A 839
PHE A 809
 None
 0.98A 1e73M-5j7tA:
undetectable		 1e73M-5j7tA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_1
(ALCOHOL
DEHYDROGENASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 4 GLU A 655
MET A 648
LEU A 651
SER A 652
 None
 1.10A 1ee2B-5j7tA:
undetectable		 1ee2B-5j7tA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 MET A 648
LEU A 651
SER A 652
 None
 0.61A 1ee2A-5j7tA:
undetectable		 1ee2A-5j7tA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 PHE A 679
TRP A 623
GLU A 663
 None
 1.09A 1mogA-5j7tA:
undetectable		 1mogA-5j7tA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 7 PHE A 324
THR A 319
VAL A 307
ILE A 320
 None
 0.80A 1p7rA-5j7tA:
undetectable		 1p7rA-5j7tA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 7 THR A 247
SER A 255
ASP A 250
LEU A 238
 None
 0.98A 2hdnE-5j7tA:
undetectable
2hdnF-5j7tA:
undetectable
2hdnH-5j7tA:
undetectable		 2hdnE-5j7tA:
5.17
2hdnF-5j7tA:
19.91
2hdnH-5j7tA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 LYS A 739
TYR A 791
PRO A 740
 None
 1.47A 2j9cC-5j7tA:
undetectable		 2j9cC-5j7tA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 ARG A 301
GLU A 345
TYR A 367
 None
 0.94A 3k37B-5j7tA:
undetectable		 3k37B-5j7tA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 TYR A 339
TYR A 379
GLU A 383
 None
 0.99A 3pfgA-5j7tA:
undetectable		 3pfgA-5j7tA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 5 PHE A 726
TYR A 692
ILE A 713
LEU A 716
 None
 1.31A 3sueC-5j7tA:
0.8		 3sueC-5j7tA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 8 VAL A 368
TYR A 367
LEU A 402
LEU A 398
 None
 1.08A 4jtrA-5j7tA:
undetectable		 4jtrA-5j7tA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 6 VAL A 401
LEU A 323
LEU A 528
PHE A 480
 None
 1.04A 4o1zA-5j7tA:
undetectable		 4o1zA-5j7tA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 PRO A 781
LEU A 780
HIS A 792
 None
 0.69A 4pevA-5j7tA:
undetectable		 4pevA-5j7tA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		3 / 3 VAL A 685
PHE A 688
ARG A 634
 None
 0.66A 4xr4B-5j7tA:
undetectable		 4xr4B-5j7tA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 5 ASP A 535
LYS A 240
ARG A 239
ILE A 536
 None
 1.13A 5a06D-5j7tA:
undetectable		 5a06D-5j7tA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		5 / 8 GLY A 215
LEU A 216
ASN A 226
GLN A 230
PHE A 480
 None
 0.36A 5xu8A-5j7tA:
27.6		 5xu8A-5j7tA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		5 / 8 GLY A 215
LEU A 216
SER A 227
GLN A 230
PHE A 480
 None
 0.62A 5xu8A-5j7tA:
27.6		 5xu8A-5j7tA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 4 PHE A 283
LEU A 238
LEU A 229
VAL A 307
 None
 1.20A 5xxiA-5j7tA:
undetectable		 5xxiA-5j7tA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		5 / 9 LEU A 609
SER A 608
PHE A 605
LEU A 602
VAL A 567
 None
 1.18A 6ftpA-5j7tA:
undetectable
6ftpB-5j7tA:
undetectable		 6ftpA-5j7tA:
9.67
6ftpB-5j7tA:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens) 		4 / 6 LEU A 258
THR A 247
GLY A 249
ARG A 543
 None
 1.36A 6gtqB-5j7tA:
undetectable
6gtqD-5j7tA:
undetectable		 6gtqB-5j7tA:
13.11
6gtqD-5j7tA:
5.64