SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 9 THR A  79
ILE A 325
VAL A 323
SER A  86
ILE A 391
 None
 1.25A 1nb9A-5j7uA:
undetectable		 1nb9A-5j7uA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 8 ILE A 314
PRO A 315
ASN A  78
GLY A 194
 None
 0.92A 3em0B-5j7uA:
4.1		 3em0B-5j7uA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 THR A 344
GLU A 346
THR A 153
VAL A 138
 None
 0.64A 3em0B-5j7uA:
4.1		 3em0B-5j7uA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 MET A 102
LEU A 393
ARG A 319
GLY A  96
 None
 1.00A 3hcnA-5j7uA:
undetectable		 3hcnA-5j7uA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 HIS A 105
VAL A 106
GLN A 107
ALA A 387
 None
 0.90A 3kp6B-5j7uA:
undetectable		 3kp6B-5j7uA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 VAL A 528
PHE A 591
VAL A 443
ILE A 548
 None
 0.96A 3zjqA-5j7uA:
undetectable		 3zjqA-5j7uA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 VAL A 528
PHE A 591
VAL A 443
ILE A 548
 None
 0.98A 3zjqB-5j7uA:
undetectable		 3zjqB-5j7uA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 SER A 381
GLY A 384
SER A 380
THR A 171
 None
 0.97A 4ac9C-5j7uA:
undetectable		 4ac9C-5j7uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 4 VAL A 473
THR A 520
GLU A 519
GLU A 521
 None
 1.43A 4l78A-5j7uA:
undetectable		 4l78A-5j7uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		3 / 3 PRO A 180
VAL A 106
HIS A 105
 None
 0.66A 4pevC-5j7uA:
undetectable		 4pevC-5j7uA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 11 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.35A 4qvnH-5j7uA:
undetectable
4qvnI-5j7uA:
undetectable		 4qvnH-5j7uA:
17.77
4qvnI-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 10 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.35A 4qvnV-5j7uA:
undetectable
4qvnW-5j7uA:
undetectable		 4qvnV-5j7uA:
17.77
4qvnW-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 11 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.34A 4qvqH-5j7uA:
undetectable
4qvqI-5j7uA:
undetectable		 4qvqH-5j7uA:
17.77
4qvqI-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 11 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.34A 4qvqV-5j7uA:
undetectable
4qvqW-5j7uA:
undetectable		 4qvqV-5j7uA:
17.77
4qvqW-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 11 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.33A 4qwuH-5j7uA:
undetectable
4qwuI-5j7uA:
undetectable		 4qwuH-5j7uA:
17.77
4qwuI-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 11 THR A 350
GLY A 360
THR A 359
ALA A 358
ASP A 129
 None
 1.34A 4qwuV-5j7uA:
undetectable
4qwuW-5j7uA:
undetectable		 4qwuV-5j7uA:
17.77
4qwuW-5j7uA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 12 VAL A 424
ILE A 609
GLY A 449
VAL A 526
LEU A 568
 None
 1.02A 4y8wA-5j7uA:
undetectable		 4y8wA-5j7uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 12 VAL A 424
LEU A 608
GLY A 449
VAL A 526
LEU A 568
 None
 0.99A 4y8wA-5j7uA:
undetectable		 4y8wA-5j7uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 12 VAL A 424
ILE A 609
GLY A 449
VAL A 526
LEU A 568
 None
 1.03A 4y8wB-5j7uA:
undetectable		 4y8wB-5j7uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 12 VAL A 424
LEU A 608
GLY A 449
VAL A 526
LEU A 568
 None
 0.97A 4y8wB-5j7uA:
undetectable		 4y8wB-5j7uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 12 VAL A 424
ILE A 609
GLY A 449
VAL A 526
LEU A 568
 None
 0.95A 4y8wC-5j7uA:
undetectable		 4y8wC-5j7uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 7 LEU A 341
THR A 343
PRO A 122
ILE A 125
 None
 1.05A 5fxtA-5j7uA:
undetectable		 5fxtA-5j7uA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		3 / 3 ASN A 429
TYR A 595
CYH A 606
 None
 0.84A 5lsuB-5j7uA:
undetectable		 5lsuB-5j7uA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 6 PHE A 599
THR A 520
ASP A 562
GLY A 564
 None
 1.19A 5mraA-5j7uA:
undetectable
5mraB-5j7uA:
undetectable		 5mraA-5j7uA:
14.00
5mraB-5j7uA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 10 ILE A 611
ILE A 446
LEU A 568
ILE A 206
ASN A 209
 None
 1.27A 5vkqA-5j7uA:
undetectable
5vkqD-5j7uA:
undetectable		 5vkqA-5j7uA:
17.23
5vkqD-5j7uA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 10 ILE A 206
ASN A 209
ILE A 611
ILE A 446
LEU A 568
 None
 1.27A 5vkqA-5j7uA:
undetectable
5vkqB-5j7uA:
undetectable		 5vkqA-5j7uA:
17.23
5vkqB-5j7uA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		5 / 10 ILE A 206
ASN A 209
ILE A 611
ILE A 446
LEU A 568
 None
 1.27A 5vkqC-5j7uA:
undetectable
5vkqD-5j7uA:
undetectable		 5vkqC-5j7uA:
17.23
5vkqD-5j7uA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5j7u MAJOR CAPSID PROTEIN
(Faustovirus) 		4 / 5 PHE A 320
THR A  79
ASP A 324
GLU A 191
 None
 1.33A 5ybbA-5j7uA:
undetectable		 5ybbA-5j7uA:
22.61