SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  21
SER A  20
ILE A  17
ILE A 451
HIS A  29
 FAD  A 601 (-3.1A)
FAD  A 601 ( 4.4A)
None
None
None
 1.16A 1kyvA-5j7xA:
2.4
1kyvE-5j7xA:
2.4		 1kyvA-5j7xA:
15.93
1kyvE-5j7xA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ILE A 451
HIS A  29
GLY A  21
SER A  20
ILE A  17
 None
None
FAD  A 601 (-3.1A)
FAD  A 601 ( 4.4A)
None
 1.17A 1kyvB-5j7xA:
2.5
1kyvC-5j7xA:
undetectable		 1kyvB-5j7xA:
15.93
1kyvC-5j7xA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ILE A 451
HIS A  29
GLY A  21
SER A  20
ILE A  17
 None
None
FAD  A 601 (-3.1A)
FAD  A 601 ( 4.4A)
None
 1.15A 1kyvC-5j7xA:
undetectable
1kyvD-5j7xA:
2.4		 1kyvC-5j7xA:
15.93
1kyvD-5j7xA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ILE A 451
HIS A  29
GLY A  21
SER A  20
ILE A  17
 None
None
FAD  A 601 (-3.1A)
FAD  A 601 ( 4.4A)
None
 1.17A 1kyvD-5j7xA:
2.4
1kyvE-5j7xA:
2.4		 1kyvD-5j7xA:
15.93
1kyvE-5j7xA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 GLY A 455
ILE A 451
GLN A 454
SER A  23
 None
None
None
FAD  A 601 (-2.7A)
 0.88A 1rs7B-5j7xA:
undetectable		 1rs7B-5j7xA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 TYR A 436
THR A 449
CYH A  64
LEU A 253
 FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
None
 1.12A 1uw6A-5j7xA:
undetectable
1uw6B-5j7xA:
undetectable		 1uw6A-5j7xA:
16.67
1uw6B-5j7xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 TYR A 436
THR A 449
CYH A  64
LEU A 253
 FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
None
 1.10A 1uw6D-5j7xA:
undetectable
1uw6E-5j7xA:
undetectable		 1uw6D-5j7xA:
16.67
1uw6E-5j7xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 TYR A 436
THR A 449
CYH A  64
LEU A 253
 FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
None
 1.10A 1uw6G-5j7xA:
undetectable
1uw6H-5j7xA:
undetectable		 1uw6G-5j7xA:
16.67
1uw6H-5j7xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 TYR A 436
THR A 449
CYH A  64
LEU A 253
 FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
None
 1.09A 1uw6P-5j7xA:
undetectable
1uw6Q-5j7xA:
undetectable		 1uw6P-5j7xA:
16.67
1uw6Q-5j7xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 LEU A 253
TYR A 436
THR A 449
CYH A  64
 None
FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
 1.16A 1uw6P-5j7xA:
undetectable
1uw6T-5j7xA:
undetectable		 1uw6P-5j7xA:
16.67
1uw6T-5j7xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 TYR A  69
GLY A 447
ASN A 446
ASP A 456
 FAD  A 601 (-3.9A)
FAD  A 601 (-3.3A)
FAD  A 601 (-4.9A)
None
 0.93A 2g72B-5j7xA:
undetectable		 2g72B-5j7xA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 LEU A 397
LEU A 400
GLN A 454
LEU A  16
VAL A 129
 None
FAD  A 601 (-4.6A)
None
None
None
 1.31A 2qd4A-5j7xA:
undetectable		 2qd4A-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 LEU A 397
LEU A 400
GLN A 454
LEU A  16
VAL A 129
 None
FAD  A 601 (-4.6A)
None
None
None
 1.21A 2qd4B-5j7xA:
undetectable		 2qd4B-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 TYR A 436
ILE A 451
GLY A 447
PHE A  96
 FAD  A 601 (-4.1A)
None
FAD  A 601 (-3.3A)
None
 0.93A 2vctD-5j7xA:
undetectable		 2vctD-5j7xA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 LEU A 402
PRO A 435
SER A 437
GLY A  19
 None
None
None
FAD  A 601 (-3.3A)
 1.10A 3hcnA-5j7xA:
undetectable		 3hcnA-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 LEU A 402
PRO A 435
SER A 437
GLY A  19
 None
None
None
FAD  A 601 (-3.3A)
 1.08A 3hcrA-5j7xA:
undetectable		 3hcrA-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 LEU A 402
PRO A 435
SER A 437
GLY A  19
 None
None
None
FAD  A 601 (-3.3A)
 1.08A 3hcrB-5j7xA:
undetectable		 3hcrB-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ALA A 145
GLY A 147
LEU A 434
PHE A  22
SER A  23
 None
FAD  A 601 (-3.4A)
None
FAD  A 601 (-4.9A)
FAD  A 601 (-2.7A)
 1.38A 3pfgA-5j7xA:
undetectable		 3pfgA-5j7xA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 THR A 128
VAL A 136
GLU A 117
 None
 0.71A 3v4tA-5j7xA:
undetectable
3v4tD-5j7xA:
undetectable		 3v4tA-5j7xA:
23.13
3v4tD-5j7xA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 GLY A 192
THR A 191
SER A 501
THR A 499
 SO4  A 602 (-3.3A)
TAM  A 603 (-3.1A)
None
None
 0.98A 4ac9C-5j7xA:
undetectable		 4ac9C-5j7xA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 VAL A 105
LYS A 107
LEU A  27
LEU A  28
LEU A  13
 None
 1.16A 4i1rA-5j7xA:
2.7		 4i1rA-5j7xA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 GLY A 455
ILE A 451
GLN A 454
SER A  23
 None
None
None
FAD  A 601 (-2.7A)
 0.92A 4kcnA-5j7xA:
undetectable		 4kcnA-5j7xA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 ASN A  88
GLU A  91
TYR A  86
GLU A  84
 None
 1.46A 4r87H-5j7xA:
undetectable		 4r87H-5j7xA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 SER A 296
LEU A 297
ASP A 298
LEU A 495
 None
 0.88A 4wozA-5j7xA:
undetectable
4wozB-5j7xA:
undetectable		 4wozA-5j7xA:
20.47
4wozB-5j7xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 PRO A 435
ILE A 451
TYR A  71
ASN A  54
ILE A  25
 None
None
None
FAD  A 601 (-3.5A)
None
 1.18A 4xe0A-5j7xA:
undetectable		 4xe0A-5j7xA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 THR A 249
ALA A 247
LEU A 243
LEU A 453
PRO A  67
 None
 1.34A 4xi3A-5j7xA:
undetectable		 4xi3A-5j7xA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 11 THR A 369
GLY A 370
PHE A 210
GLU A 380
GLU A 208
 None
 1.32A 4xt7A-5j7xA:
undetectable		 4xt7A-5j7xA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 GLY A 447
THR A 449
GLN A 514
ASN A 517
LEU A 522
 FAD  A 601 (-3.3A)
None
None
None
None
 1.33A 5fhzC-5j7xA:
2.1		 5fhzC-5j7xA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 THR A 420
LEU A 450
ASN A 517
GLN A 287
 None
 1.14A 5tudA-5j7xA:
undetectable		 5tudA-5j7xA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLU A 480
VAL A 532
LEU A 461
SER A 427
ARG A 413
 None
 1.12A 5vooC-5j7xA:
undetectable		 5vooC-5j7xA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLU A 480
VAL A 532
LEU A 461
SER A 427
ARG A 413
 None
 1.05A 5vooE-5j7xA:
undetectable		 5vooE-5j7xA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLU A 480
VAL A 532
LEU A 461
SER A 427
ARG A 413
 None
 1.02A 5vopB-5j7xA:
undetectable		 5vopB-5j7xA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 PRO A 477
SER A 427
PHE A 429
VAL A 408
ARG A 413
 None
 1.50A 6b89A-5j7xA:
undetectable		 6b89A-5j7xA:
9.65