SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 7 VAL A 178
SER A  93
PHE A  94
ALA A  96
 None
 0.83A 1j8uA-5j7zA:
undetectable		 1j8uA-5j7zA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 9 LEU A  52
ILE A 337
GLY A  55
TYR A 388
PHE A 340
 None
 1.44A 1td7A-5j7zA:
undetectable		 1td7A-5j7zA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 PHE A 424
TYR A 430
TYR A 434
 None
 1.08A 1x70B-5j7zA:
undetectable		 1x70B-5j7zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 8 TYR A 410
PHE A 408
HIS A  54
LEU A  52
 None
 1.11A 1x8vA-5j7zA:
undetectable		 1x8vA-5j7zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ALA A 118
GLY A 114
ASN A  58
GLY A 208
LEU A 128
 None
 0.97A 2hw2A-5j7zA:
undetectable		 2hw2A-5j7zA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ASN A 213
GLU A 214
HIS A 291
TYR A 293
TRP A 365
 BGC  A 604 (-3.2A)
18C  A 607 (-3.0A)
None
18C  A 607 (-4.0A)
BGC  A 604 (-3.6A)
 0.57A 2v3dA-5j7zA:
7.0		 2v3dA-5j7zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z71_C_PNVC904_1
(PENICILLIN ACYLASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 10 GLY A  55
GLN A 363
ASN A  86
THR A 338
GLU A 210
 None
 1.38A 2z71A-5j7zA:
undetectable
2z71C-5j7zA:
undetectable		 2z71A-5j7zA:
20.59
2z71C-5j7zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 GLY A 134
ASP A 133
LEU A 171
ASP A 176
GLU A 214
 None
BGC  A 604 (-2.6A)
None
None
18C  A 607 (-3.0A)
 1.05A 2zw9B-5j7zA:
undetectable		 2zw9B-5j7zA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 THR A 421
PRO A 420
THR A 453
 None
 0.88A 316dC-5j7zA:
undetectable		 316dC-5j7zA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 8 ILE A  77
LEU A  80
ASN A  58
VAL A  88
 None
 0.81A 3dcjB-5j7zA:
undetectable		 3dcjB-5j7zA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ILE A 254
VAL A 247
GLY A 194
LEU A 109
ARG A 199
 None
 1.14A 3em0B-5j7zA:
undetectable		 3em0B-5j7zA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ALA A 289
GLN A 132
LEU A 243
VAL A 256
THR A 338
 None
 1.12A 3ix9A-5j7zA:
undetectable		 3ix9A-5j7zA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 4 GLY A 140
TYR A 165
GLY A 134
ASP A 133
 None
None
None
BGC  A 604 (-2.6A)
 0.83A 3kl3A-5j7zA:
9.2		 3kl3A-5j7zA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 ARG A  89
ASP A 129
HIS A 131
ASP A 133
TYR A 293
 None
None
BGC  A 604 (-4.5A)
BGC  A 604 (-2.6A)
18C  A 607 (-4.0A)
 1.49A 3lmyA-5j7zA:
7.1		 3lmyA-5j7zA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 12 HIS A 125
GLY A 205
VAL A  88
GLY A  46
ALA A 391
 None
 1.09A 3sueC-5j7zA:
undetectable		 3sueC-5j7zA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 10 THR A  71
LEU A  66
LEU A 112
VAL A  88
VAL A 126
 None
 1.31A 4c9nB-5j7zA:
undetectable		 4c9nB-5j7zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 9 THR A  71
LEU A  66
LEU A 112
VAL A  88
VAL A 126
 None
 1.32A 4c9pA-5j7zA:
undetectable		 4c9pA-5j7zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		5 / 10 THR A  71
LEU A  66
LEU A 112
VAL A  88
VAL A 126
 None
 1.31A 4c9pB-5j7zA:
undetectable		 4c9pB-5j7zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 7 GLY A  48
ALA A 391
TYR A  47
GLU A 422
 None
 0.93A 4hyfA-5j7zA:
undetectable		 4hyfA-5j7zA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 8 GLY A  48
ALA A 391
TYR A  47
GLU A 422
 None
 0.90A 4hyfB-5j7zA:
undetectable		 4hyfB-5j7zA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 5 ALA A 355
HIS A  54
MET A 399
LEU A 352
 None
 1.45A 5dzkf-5j7zA:
2.5
5dzkt-5j7zA:
undetectable		 5dzkf-5j7zA:
18.38
5dzkt-5j7zA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 8 MET A 124
ILE A  79
TYR A 364
LEU A 352
 None
 0.96A 5ieoA-5j7zA:
undetectable		 5ieoA-5j7zA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 5 PHE A 340
SER A 339
GLN A 317
ASP A 325
 None
BGC  A 604 ( 4.5A)
None
None
 1.38A 5kpcA-5j7zA:
undetectable		 5kpcA-5j7zA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		4 / 6 LEU A 135
SER A 136
PHE A 144
ASP A  95
 None
 1.17A 5om3A-5j7zA:
undetectable
5om3B-5j7zA:
undetectable		 5om3A-5j7zA:
10.59
5om3B-5j7zA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 THR A 120
MET A 124
HIS A 125
 None
 0.76A 5uunA-5j7zA:
undetectable		 5uunA-5j7zA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 THR A 338
GLU A 210
HIS A 131
 None
None
BGC  A 604 (-4.5A)
 0.90A 5xiqB-5j7zA:
undetectable		 5xiqB-5j7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 THR A 338
GLU A 210
HIS A 131
 None
None
BGC  A 604 (-4.5A)
 0.92A 5xiqD-5j7zA:
undetectable		 5xiqD-5j7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE
(Rhodococcus
hoagii) 		3 / 3 GLN A 241
TRP A 258
VAL A 256
 None
 0.75A 6auuA-5j7zA:
0.6		 6auuA-5j7zA:
20.11