SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j8d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		3 / 4 VAL A 143
TRP A 138
TRP A  46
 None
 1.21A 1gmkA-5j8dA:
undetectable
1gmkB-5j8dA:
undetectable		 1gmkA-5j8dA:
5.21
1gmkB-5j8dA:
5.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		6 / 8 TYR A  68
PHE A  70
ASN A  71
LYS A  74
GLU A 165
GLY A 166
 DND  A 302 (-4.8A)
DND  A 302 ( 4.7A)
FMN  A 301 ( 3.1A)
DND  A 302 ( 2.8A)
FMN  A 301 (-3.6A)
FMN  A 301 (-3.5A)
 0.70A 1ykiA-5j8dA:
34.1
1ykiB-5j8dA:
34.2		 1ykiA-5j8dA:
87.96
1ykiB-5j8dA:
87.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		6 / 8 TYR A  68
PHE A  70
ASN A  71
LYS A  74
GLU A 165
GLY A 166
 DND  A 302 (-4.8A)
DND  A 302 ( 4.7A)
FMN  A 301 ( 3.1A)
DND  A 302 ( 2.8A)
FMN  A 301 (-3.6A)
FMN  A 301 (-3.5A)
 0.73A 1ykiA-5j8dA:
34.1
1ykiB-5j8dA:
34.2		 1ykiA-5j8dA:
87.96
1ykiB-5j8dA:
87.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		6 / 8 TYR A  68
PHE A  70
ASN A  71
LYS A  74
GLU A 165
GLY A 166
 DND  A 302 (-4.8A)
DND  A 302 ( 4.7A)
FMN  A 301 ( 3.1A)
DND  A 302 ( 2.8A)
FMN  A 301 (-3.6A)
FMN  A 301 (-3.5A)
 0.71A 1ykiC-5j8dA:
34.1
1ykiD-5j8dA:
33.8		 1ykiC-5j8dA:
87.96
1ykiD-5j8dA:
87.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		6 / 8 TYR A  68
PHE A  70
ASN A  71
LYS A  74
GLU A 165
GLY A 166
 DND  A 302 (-4.8A)
DND  A 302 ( 4.7A)
FMN  A 301 ( 3.1A)
DND  A 302 ( 2.8A)
FMN  A 301 (-3.6A)
FMN  A 301 (-3.5A)
 0.69A 1ykiC-5j8dA:
34.1
1ykiD-5j8dA:
33.8		 1ykiC-5j8dA:
87.96
1ykiD-5j8dA:
87.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		4 / 8 ASP A  91
ASP A  92
ASP A 134
TRP A 138
 None
 1.19A 3havA-5j8dA:
undetectable		 3havA-5j8dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5j8d OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE
(Enterobacter
cloacae) 		3 / 3 LEU A 132
HIS A 128
MET A 127
 None
 0.86A 3thrD-5j8dA:
undetectable		 3thrD-5j8dA:
23.89