SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 ALA A 494
VAL A 489
TRP A 108
 None
 0.86A 1gmkC-5j90A:
undetectable
1gmkD-5j90A:
undetectable		 1gmkC-5j90A:
3.64
1gmkD-5j90A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 7 LEU A 224
LEU A 140
TYR A 210
LEU A 347
 None
 0.99A 1kt3A-5j90A:
undetectable		 1kt3A-5j90A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 226
LEU A 183
GLU A 452
HIS A 146
GLU A 143
 None
 1.28A 1kw0A-5j90A:
undetectable		 1kw0A-5j90A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 226
LEU A 183
GLU A 452
HIS A 146
GLU A 143
 None
 1.26A 1mmkA-5j90A:
undetectable		 1mmkA-5j90A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 10 ALA A 229
GLU A 243
LEU A 183
MET A 348
LEU A 356
 None
 1.34A 1qkuA-5j90A:
undetectable		 1qkuA-5j90A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 10 ALA A 229
GLU A 243
LEU A 183
MET A 348
LEU A 356
 None
 1.33A 1qkuC-5j90A:
undetectable		 1qkuC-5j90A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 8 PHE A  88
ILE A 336
ILE A 283
THR A  86
 None
 0.89A 1sbrA-5j90A:
undetectable		 1sbrA-5j90A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 7 PHE A  88
ILE A 336
ILE A 283
THR A  86
 None
 0.93A 1sbrB-5j90A:
undetectable		 1sbrB-5j90A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 ASN A 102
TRP A 103
GLN A 490
 None
 1.09A 1xoqA-5j90A:
undetectable		 1xoqA-5j90A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 GLY A 369
GLY A 368
VAL A 248
LEU A 362
LEU A 226
 None
None
EDO  A 604 (-3.4A)
None
None
 1.06A 1ya4C-5j90A:
undetectable		 1ya4C-5j90A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 7 ARG A 219
GLY A 253
SER A 216
PHE A 252
 None
EDO  A 604 (-3.0A)
None
None
 1.10A 2c8aD-5j90A:
undetectable		 2c8aD-5j90A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 TYR A 112
GLU A 492
THR A 502
 None
 0.92A 2y7hB-5j90A:
undetectable		 2y7hB-5j90A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 9 THR A  95
VAL A 318
SER A 308
ILE A 336
GLY A  87
 None
 1.03A 3cv9A-5j90A:
undetectable		 3cv9A-5j90A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 9 THR A  95
VAL A 318
SER A 334
ILE A 336
GLY A  87
 None
 1.27A 3cv9A-5j90A:
undetectable		 3cv9A-5j90A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 140
GLY A 144
ARG A 227
PHE A 262
MET A 207
 None
 1.31A 3h52C-5j90A:
undetectable		 3h52C-5j90A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 GLU A 376
GLY A 378
PHE A 383
ALA A 445
GLN A 441
 None
 1.06A 3nvkF-5j90A:
0.8
3nvkJ-5j90A:
undetectable		 3nvkF-5j90A:
23.68
3nvkJ-5j90A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 GLU A 376
TYR A 394
PHE A 383
ALA A 445
GLN A 441
 None
 1.16A 3nvkF-5j90A:
0.8
3nvkJ-5j90A:
undetectable		 3nvkF-5j90A:
23.68
3nvkJ-5j90A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 9 ASP A  76
GLY A 450
ILE A 336
ILE A 345
ILE A 276
 None
 0.95A 3s53A-5j90A:
undetectable		 3s53A-5j90A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 9 GLY A 446
ALA A 445
ILE A 379
ILE A 292
ILE A 438
 None
 0.90A 3s53A-5j90A:
undetectable		 3s53A-5j90A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 PHE A 333
SER A 308
GLN A 310
 None
 0.84A 3smtA-5j90A:
undetectable		 3smtA-5j90A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 ARG A 386
ASP A  76
GLN A  71
 None
 0.90A 4azsA-5j90A:
undetectable		 4azsA-5j90A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 7 GLY A 369
GLY A 368
ASN A 366
GLU A 373
 None
 1.03A 4fgkB-5j90A:
undetectable		 4fgkB-5j90A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 ARG A 227
GLN A 451
GLU A 449
 None
 0.93A 4tvtA-5j90A:
undetectable		 4tvtA-5j90A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 8 ALA A 350
ALA A 381
ALA A 377
ALA A 353
 None
 0.75A 4twdF-5j90A:
undetectable
4twdG-5j90A:
undetectable
4twdH-5j90A:
0.1
4twdI-5j90A:
undetectable
4twdJ-5j90A:
undetectable		 4twdF-5j90A:
20.08
4twdG-5j90A:
20.08
4twdH-5j90A:
20.08
4twdI-5j90A:
20.08
4twdJ-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 8 ALA A 353
ALA A 350
ALA A 381
ALA A 377
 None
 0.80A 4twdF-5j90A:
undetectable
4twdG-5j90A:
undetectable
4twdH-5j90A:
0.1
4twdI-5j90A:
undetectable
4twdJ-5j90A:
undetectable		 4twdF-5j90A:
20.08
4twdG-5j90A:
20.08
4twdH-5j90A:
20.08
4twdI-5j90A:
20.08
4twdJ-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 10 GLY A 482
THR A 515
VAL A 483
SER A 473
LEU A  99
 None
 1.25A 4yb6B-5j90A:
undetectable
4yb6C-5j90A:
undetectable		 4yb6B-5j90A:
20.70
4yb6C-5j90A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 10 SER A 473
LEU A  99
GLY A 482
THR A 515
VAL A 483
 None
 1.24A 4yb6D-5j90A:
undetectable
4yb6E-5j90A:
undetectable		 4yb6D-5j90A:
20.70
4yb6E-5j90A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 ASP A  76
GLY A 450
ILE A 336
ILE A 345
ILE A 276
 None
 0.86A 5e5kB-5j90A:
undetectable		 5e5kB-5j90A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 11 VAL A 115
MET A 148
MET A 145
GLN A  70
GLY A 105
 None
 1.39A 5g6sA-5j90A:
undetectable
5g6sG-5j90A:
undetectable		 5g6sA-5j90A:
20.08
5g6sG-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 11 VAL A 115
MET A 148
MET A 145
GLN A  70
GLY A 105
 None
 1.35A 5g6sB-5j90A:
undetectable
5g6sC-5j90A:
undetectable		 5g6sB-5j90A:
20.08
5g6sC-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 MET A 145
GLN A  70
GLY A 105
VAL A 115
MET A 148
 None
 1.40A 5g6sB-5j90A:
undetectable
5g6sC-5j90A:
undetectable		 5g6sB-5j90A:
20.08
5g6sC-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 11 VAL A 115
MET A 148
MET A 145
GLN A  70
GLY A 105
 None
 1.39A 5g6sE-5j90A:
undetectable
5g6sH-5j90A:
undetectable		 5g6sE-5j90A:
20.08
5g6sH-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 10 MET A 145
GLN A  70
GLY A 105
VAL A 115
MET A 148
 None
 1.34A 5g6sE-5j90A:
0.0
5g6sH-5j90A:
0.0		 5g6sE-5j90A:
20.08
5g6sH-5j90A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 VAL A 115
ALA A 119
THR A 205
PHE A 202
PHE A  51
 None
 1.35A 5hgcA-5j90A:
undetectable		 5hgcA-5j90A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5j90 RAGB/SUSD DOMAIN
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 VAL A 268
LEU A 140
MET A  54
 None
 0.58A 5ikrA-5j90A:
undetectable		 5ikrA-5j90A:
21.93