SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_F_TFPF211_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	5j92	PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE (Paraburkholderia xenovorans)	4 / 7	LEU A 43 PHE A 45 PHE A 58 SER A 26	None	0.94A	1wrlE-5j92A: undetectable 1wrlF-5j92A: undetectable	1wrlE-5j92A: 16.04 1wrlF-5j92A: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_A_9PLA501_1 (CYTOCHROME P450 2E1)	5j92	PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE (Paraburkholderia xenovorans)	4 / 6	PHE A 45 LEU A 25 PHE A 62 LEU A 3	None	1.01A	3t3zA-5j92A: undetectable	3t3zA-5j92A: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_B_RCXB601_2 (PROSTAGLANDIN G/H SYNTHASE 2)	5j92	PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE (Paraburkholderia xenovorans)	4 / 4	LEU A 43 ARG A 15 ILE A 16 PHE A 45	None	1.25A	5kirB-5j92A: undetectable	5kirB-5j92A: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DCH_A_ACTA401_0 (SCOE PROTEIN)	5j92	PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE (Paraburkholderia xenovorans)	4 / 5	THR A 109 HIS A 114 ASP A 116 HIS A 263	None FE2 A 401 (-3.6A) FE2 A 401 (-2.8A) FE2 A 401 (-3.6A)	1.05A	6dchA-5j92A: 25.6	6dchA-5j92A: 28.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_F_TFPF211_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","5j92","PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE","Paraburkholderia xenovorans",4,"LEU A  43;PHE A  45;PHE A  58;SER A  26","None","0.94A","1wrlE-5j92A:undetectable;1wrlF-5j92A:undetectable","1wrlE-5j92A:16.04;1wrlF-5j92A:16.04"],["3T3Z_A_9PLA501_1","CYTOCHROME P450 2E1","5j92","PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE","Paraburkholderia xenovorans",4,"PHE A  45;LEU A  25;PHE A  62;LEU A   3","None","1.01A","3t3zA-5j92A:undetectable","3t3zA-5j92A:20.62"],["5KIR_B_RCXB601_2","PROSTAGLANDIN G\/H SYNTHASE 2","5j92","PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE","Paraburkholderia xenovorans",4,"LEU A  43;ARG A  15;ILE A  16;PHE A  45","None","1.25A","5kirB-5j92A:undetectable","5kirB-5j92A:18.52"],["6DCH_A_ACTA401_0","SCOE PROTEIN","5j92","PUTATIVE ALPHA KG DEPENDENT 2,4-D DIOXYGENASE","Paraburkholderia xenovorans",4,"THR A 109;HIS A 114;ASP A 116;HIS A 263","None;FE2 A 401 (-3.6A);FE2 A 401 (-2.8A);FE2 A 401 (-3.6A)","1.05A","6dchA-5j92A:25.6","6dchA-5j92A:28.77"]]