SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		4 / 5 GLY C  63
GLN B 158
VAL C  98
SER C 116
 None
 1.31A 1p6kB-5j98C:
undetectable		 1p6kB-5j98C:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		4 / 5 GLY C  63
GLN B 158
VAL C  98
SER C 116
 None
 1.39A 1rs6B-5j98C:
undetectable		 1rs6B-5j98C:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		5 / 12 GLY B 131
PHE B 128
ASN C 137
PRO C 139
ALA B 168
 None
 1.18A 1sg9C-5j98B:
undetectable		 1sg9C-5j98B:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		4 / 5 GLY C  63
GLN B 158
VAL C  98
SER C 116
 None
 1.32A 1zzuB-5j98C:
undetectable		 1zzuB-5j98C:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus) 		4 / 4 ASP C  46
TRP B  38
ILE C  48
ARG C  44
 None
 1.07A 2htqA-5j98C:
undetectable		 2htqA-5j98C:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus) 		4 / 6 ASP C  46
TRP B  38
ILE C  48
ARG C  44
 None
 1.02A 3ckzA-5j98C:
undetectable		 3ckzA-5j98C:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5j98 VP3
(Slow
bee
paralysis
virus) 		5 / 12 THR C 108
VAL C 101
ILE C 319
TYR C 350
THR C 324
 None
 1.43A 3elzA-5j98C:
undetectable		 3elzA-5j98C:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5j98 VP2
(Slow
bee
paralysis
virus) 		4 / 4 VAL B  12
THR B  11
GLU B  21
GLU B   9
 None
 1.38A 4l78A-5j98B:
undetectable		 4l78A-5j98B:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		3 / 3 ASP C  52
TRP B  38
SER B  31
 None
 1.03A 4lrhA-5j98C:
undetectable		 4lrhA-5j98C:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5j98 VP3
(Slow
bee
paralysis
virus) 		4 / 6 TYR C 377
ASP C 156
VAL C 207
ALA C 208
 None
 1.07A 4nkvC-5j98C:
undetectable		 4nkvC-5j98C:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		4 / 7 PRO B 153
THR C 231
ILE C 229
ASP C  69
 None
 1.04A 4pcuA-5j98B:
undetectable		 4pcuA-5j98B:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5j98 VP2
(Slow
bee
paralysis
virus) 		5 / 12 THR B  99
ASN B 103
ASP B  89
ILE B 109
ASN B 100
 None
 1.39A 4pooB-5j98B:
undetectable		 4pooB-5j98B:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 5j98 VP2
(Slow
bee
paralysis
virus) 		5 / 12 ALA B 155
GLU B 212
GLY B  73
PHE B 210
GLN B  78
 None
 1.11A 4uilH-5j98B:
undetectable
4uilL-5j98B:
undetectable		 4uilH-5j98B:
21.53
4uilL-5j98B:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 5j98 VP3
(Slow
bee
paralysis
virus) 		5 / 12 GLY C 371
TYR C 110
VAL C 260
GLY C 349
LEU C 370
 None
 1.20A 5hg0A-5j98C:
undetectable		 5hg0A-5j98C:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 5j98 VP3
(Slow
bee
paralysis
virus) 		3 / 3 ILE C 150
PRO C 151
ILE C 153
 None
 0.37A 5hw8F-5j98C:
undetectable		 5hw8F-5j98C:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 5j98 VP3
(Slow
bee
paralysis
virus) 		5 / 12 ILE C 232
LEU C 145
GLU C 179
PHE C 135
GLY C 136
 None
 1.33A 5il1A-5j98C:
undetectable		 5il1A-5j98C:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5j98 VP3
(Slow
bee
paralysis
virus) 		5 / 12 ILE C 232
LEU C 145
GLU C 179
PHE C 135
GLY C 136
 None
 1.33A 5k7uA-5j98C:
undetectable		 5k7uA-5j98C:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5j98 VP2
VP3
(Slow
bee
paralysis
virus;
Slow
bee
paralysis
virus) 		4 / 5 GLY C  63
GLN B 158
VAL C  98
SER C 116
 None
 1.37A 5vunA-5j98C:
undetectable		 5vunA-5j98C:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5j98 VP3
(Slow
bee
paralysis
virus) 		4 / 6 LEU C 367
TYR C 110
ASP C 416
GLU C 372
 None
 1.33A 6djzC-5j98C:
undetectable		 6djzC-5j98C:
19.77