SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5j9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FWD_A_BO2A801_1 (TTC1975 PEPTIDASE)	5j9s	PROTEIN ENL (Homo sapiens)	5 / 9	VAL A 9 GLU A 120 VAL A 98 GLY A 38 ALA A 138	None	1.08A	4fwdA-5j9sA: undetectable	4fwdA-5j9sA: 11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GC9_A_ACTA402_0 (DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL)	5j9s	PROTEIN ENL (Homo sapiens)	3 / 3	LYS A 134 TYR A 133 ARG A 137	None	1.39A	4gc9A-5j9sA: undetectable	4gc9A-5j9sA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L6V_A_PQNA2001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX)	5j9s	PROTEIN ENL (Homo sapiens)	5 / 9	MET A 83 PHE A 81 ALA A 17 LEU A 106 GLY A 80	None	1.35A	4l6va-5j9sA: undetectable 4l6vf-5j9sA: undetectable	4l6va-5j9sA: 11.11 4l6vf-5j9sA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	5j9s	PROTEIN ENL (Homo sapiens)	4 / 6	VAL A 87 LYS A 50 ILE A 44 LYS A 90	None SO4 A 201 (-3.2A) None None	0.90A	5q1sA-5j9sA: undetectable	5q1sA-5j9sA: 18.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FWD_A_BO2A801_1","TTC1975 PEPTIDASE","5j9s","PROTEIN ENL","Homo sapiens",5,"VAL A   9;GLU A 120;VAL A  98;GLY A  38;ALA A 138","None","1.08A","4fwdA-5j9sA:undetectable","4fwdA-5j9sA:11.28"],["4GC9_A_ACTA402_0","DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL","5j9s","PROTEIN ENL","Homo sapiens",3,"LYS A 134;TYR A 133;ARG A 137","None","1.39A","4gc9A-5j9sA:undetectable","4gc9A-5j9sA:21.59"],["4L6V_A_PQNA2001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX","5j9s","PROTEIN ENL","Homo sapiens",5,"MET A  83;PHE A  81;ALA A  17;LEU A 106;GLY A  80","None","1.35A","4l6va-5j9sA:undetectable;4l6vf-5j9sA:undetectable","4l6va-5j9sA:11.11;4l6vf-5j9sA:18.87"],["5Q1S_A_AWYA1103_0","DNA CROSS-LINK REPAIR 1A PROTEIN","5j9s","PROTEIN ENL","Homo sapiens",4,"VAL A  87;LYS A  50;ILE A  44;LYS A  90","None;SO4 A 201 (-3.2A);None;None","0.90A","5q1sA-5j9sA:undetectable","5q1sA-5j9sA:18.52"]]