SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ja1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 VAL A 753
VAL A 755
TRP A 652
 75C  A1301 (-4.7A)
None
None
 0.98A 1bdwA-5ja1A:
undetectable
1bdwB-5ja1A:
undetectable		 1bdwA-5ja1A:
2.26
1bdwB-5ja1A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 PHE A 824
ILE A 601
TYR A 599
GLN A 617
ALA A 619
 None
 1.41A 1fm4A-5ja1A:
2.4		 1fm4A-5ja1A:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 TRP A 780
VAL A 755
TRP A 757
 None
 1.22A 1gmkC-5ja1A:
undetectable
1gmkD-5ja1A:
undetectable		 1gmkC-5ja1A:
2.26
1gmkD-5ja1A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ASP A 377
GLY A 346
PHE A 345
TYR A 401
ALA A 396
 None
 1.35A 1ju6A-5ja1A:
undetectable		 1ju6A-5ja1A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 ASP A 377
GLY A 346
PHE A 345
TYR A 401
ALA A 396
 None
 1.35A 1ju6C-5ja1A:
undetectable		 1ju6C-5ja1A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli;
Escherichia
coli) 		4 / 5 ILE A 862
ARG A 903
ASP A 857
ASN B   5
 None
CL  A1302 (-3.7A)
None
None
 1.10A 1kiaD-5ja1A:
2.3		 1kiaD-5ja1A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.04A 1m8eB-5ja1A:
undetectable		 1m8eB-5ja1A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 VAL A 246
LEU A 243
LEU A 255
LEU A 251
LEU A 258
 None
 0.98A 1mx1C-5ja1A:
9.9		 1mx1C-5ja1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 VAL A 246
LEU A 243
LEU A 255
LEU A 251
LEU A 258
 None
 1.05A 1mx1F-5ja1A:
9.7		 1mx1F-5ja1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 ASP A 432
TYR A 439
LEU A 263
PRO A 796
THR A 405
 None
 1.41A 1mxfA-5ja1A:
4.1		 1mxfA-5ja1A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ASP A 432
TYR A 439
LEU A 263
PRO A 796
THR A 405
 None
 1.43A 1mxfB-5ja1A:
4.3		 1mxfB-5ja1A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ASP A 432
TYR A 439
LEU A 263
PRO A 796
THR A 405
 None
 1.43A 1mxfC-5ja1A:
4.3		 1mxfC-5ja1A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_D_MTXD4278_1
(PTERIDINE REDUCTASE
2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ASP A 432
TYR A 439
LEU A 263
PRO A 796
THR A 405
 None
 1.42A 1mxfD-5ja1A:
4.1		 1mxfD-5ja1A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli;
Escherichia
coli) 		4 / 4 ILE A 862
ARG A 903
ASP A 857
ASN B   5
 None
CL  A1302 (-3.7A)
None
None
 1.22A 1nbiC-5ja1A:
2.2		 1nbiC-5ja1A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli;
Escherichia
coli) 		4 / 4 ILE A 862
ARG A 903
ASP A 857
ASN B   5
 None
CL  A1302 (-3.7A)
None
None
 1.23A 1nbiD-5ja1A:
2.2		 1nbiD-5ja1A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.08A 1nodB-5ja1A:
undetectable		 1nodB-5ja1A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.19A 1qomA-5ja1A:
undetectable		 1qomA-5ja1A:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 LEU A 520
LEU A 512
MET A 666
 None
 0.81A 1ya3B-5ja1A:
undetectable		 1ya3B-5ja1A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFM_A_TOPA1290_1
(PTERIDINE REDUCTASE
1)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 ASP A 432
LEU A 435
TYR A 439
LEU A 263
HIS A 409
 None
 1.40A 2bfmA-5ja1A:
undetectable
2bfmD-5ja1A:
4.6		 2bfmA-5ja1A:
12.18
2bfmD-5ja1A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli) 		3 / 3 PHE B  24
VAL B  40
TRP B  52
 None
 0.74A 2cc8A-5ja1B:
undetectable		 2cc8A-5ja1B:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli) 		3 / 3 PHE B  24
VAL B  40
TRP B  52
 None
 0.72A 2ccbA-5ja1B:
undetectable		 2ccbA-5ja1B:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 LEU A 575
ALA A 521
VAL A 508
TYR A 577
LEU A 581
 None
 1.18A 2japC-5ja1A:
2.2		 2japC-5ja1A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.08A 2nodB-5ja1A:
undetectable		 2nodB-5ja1A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 GLY A1004
GLY A1003
VAL A1029
LEU A1012
 None
 0.76A 2oa1B-5ja1A:
2.2		 2oa1B-5ja1A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 LEU A 291
PHE A 354
ILE A 274
GLU A 393
 None
 0.87A 2opxA-5ja1A:
3.3		 2opxA-5ja1A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 PHE B   7
PRO B  34
LEU B  33
ALA A 826
LEU B  17
 None
 1.17A 2vcvD-5ja1B:
undetectable		 2vcvD-5ja1B:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 PHE B   7
PRO B  34
LEU B  33
ALA A 826
LEU B  17
 None
 1.21A 2vcvE-5ja1B:
undetectable		 2vcvE-5ja1B:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 PHE B   7
PRO B  34
LEU B  33
ALA A 826
LEU B  17
 None
 1.24A 2vcvH-5ja1B:
undetectable		 2vcvH-5ja1B:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 PHE B   7
PRO B  34
LEU B  33
ALA A 826
LEU B  17
 None
 1.15A 2vcvI-5ja1B:
undetectable		 2vcvI-5ja1B:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 9 PHE A 174
ALA A 175
VAL A 178
GLU A 179
 None
 0.47A 2vufA-5ja1A:
undetectable		 2vufA-5ja1A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
(Escherichia
coli) 		3 / 3 PHE B  24
VAL B  40
TRP B  52
 None
 0.72A 2vx9A-5ja1B:
undetectable		 2vx9A-5ja1B:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 6 ASP A 542
TYR A 539
PHE A 566
LEU A 535
 None
 1.21A 2w98A-5ja1A:
undetectable
2w98B-5ja1A:
undetectable		 2w98A-5ja1A:
14.42
2w98B-5ja1A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 GLY A 723
GLY A 747
THR A 749
ARG A 866
 75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.33A 2wd9A-5ja1A:
39.6		 2wd9A-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 GLY A 723
GLY A 747
THR A 749
ARG A 866
 75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.30A 2wd9B-5ja1A:
41.3		 2wd9B-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 THR A 603
GLY A 723
GLY A 747
THR A 749
ARG A 866
 None
75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.51A 2wd9C-5ja1A:
41.0		 2wd9C-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 SER A 592
SER A 458
ALA A 528
GLY A 529
ALA A 530
 None
 1.10A 2xh9A-5ja1A:
undetectable		 2xh9A-5ja1A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 0.98A 3e68A-5ja1A:
undetectable		 3e68A-5ja1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.03A 3e6tB-5ja1A:
undetectable		 3e6tB-5ja1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ARG A 623
ILE A 659
TRP A 656
 None
 1.15A 3e7iB-5ja1A:
undetectable		 3e7iB-5ja1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ILE A 872
SER A 604
SER A 606
 None
 0.61A 3iltH-5ja1A:
undetectable		 3iltH-5ja1A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 HIS A1119
LEU A1084
LEU A1135
CYH A1070
 None
 0.99A 3lm8B-5ja1A:
undetectable
3lm8D-5ja1A:
undetectable		 3lm8B-5ja1A:
9.87
3lm8D-5ja1A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 5 ASP A 788
LEU A 787
PRO B   6
PHE B   7
 None
 1.06A 3s3vA-5ja1A:
undetectable		 3s3vA-5ja1A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ASN A 128
ALA A 126
ARG A 129
 None
 0.66A 3tj7C-5ja1A:
1.6
3tj7D-5ja1A:
undetectable		 3tj7C-5ja1A:
9.37
3tj7D-5ja1A:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 THR A 690
VAL A 687
GLU A 653
 None
 0.74A 3v4tA-5ja1A:
undetectable
3v4tD-5ja1A:
undetectable		 3v4tA-5ja1A:
16.16
3v4tD-5ja1A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 ASP A 648
GLY A 723
THR A 749
LYS A 861
 75C  A1301 (-3.3A)
75C  A1301 (-3.4A)
75C  A1301 (-4.5A)
75C  A1301 ( 2.8A)
 0.81A 3vnsA-5ja1A:
49.1		 3vnsA-5ja1A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 ARG A 151
ALA A  55
ASP A  56
LEU A 140
ILE A 149
 None
 1.11A 3wsjA-5ja1A:
undetectable		 3wsjA-5ja1A:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 TRP A 780
VAL A 755
TRP A 626
 None
 1.01A 3zq8C-5ja1A:
undetectable
3zq8D-5ja1A:
undetectable		 3zq8C-5ja1A:
2.26
3zq8D-5ja1A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 6 GLY A 288
PRO A 289
LEU A 140
VAL A 141
 None
 0.82A 4dubA-5ja1A:
undetectable		 4dubA-5ja1A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 LEU A 522
TYR A 577
ALA A 494
ASP A 506
GLY A 529
 None
 1.27A 4j7xA-5ja1A:
3.3		 4j7xA-5ja1A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 5 GLU A 851
SER A 772
ARG A 843
SER A 771
 None
 1.20A 4k17B-5ja1A:
2.2		 4k17B-5ja1A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 6 LEU A 853
GLY A 854
VAL A 841
ALA A 799
 None
 0.21A 4o0wA-5ja1A:
undetectable		 4o0wA-5ja1A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 LEU A1139
LEU A1224
ALA A1220
VAL A1186
LEU A1187
 None
 1.09A 4p65C-5ja1A:
undetectable
4p65D-5ja1A:
undetectable
4p65J-5ja1A:
undetectable
4p65L-5ja1A:
undetectable		 4p65C-5ja1A:
1.55
4p65D-5ja1A:
2.38
4p65J-5ja1A:
2.38
4p65L-5ja1A:
2.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 GLY A 373
PRO A 374
ALA A 220
 None
 0.55A 4qn9B-5ja1A:
undetectable		 4qn9B-5ja1A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 THR B  66
GLY A 505
THR B  63
VAL A 502
 None
 0.98A 4qwpB-5ja1B:
undetectable		 4qwpB-5ja1B:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ASP A 536
ARG A 514
PRO A 644
 None
 1.01A 4wanC-5ja1A:
2.1		 4wanC-5ja1A:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 CYH A 731
LEU A 726
LEU A 697
THR A 690
ALA A 760
 None
 1.04A 4x1iD-5ja1A:
undetectable		 4x1iD-5ja1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 ASP A 648
GLY A 723
THR A 749
LYS A 861
 75C  A1301 (-3.3A)
75C  A1301 (-3.4A)
75C  A1301 (-4.5A)
75C  A1301 ( 2.8A)
 1.14A 4zxiA-5ja1A:
48.9		 4zxiA-5ja1A:
28.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 6 TYR A 631
GLY A 776
SER A 756
LEU A 745
 None
 1.21A 5bphD-5ja1A:
3.4		 5bphD-5ja1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ASP A 840
GLU A 750
SER A 772
 75C  A1301 (-3.0A)
None
None
 0.81A 5bw4B-5ja1A:
undetectable		 5bw4B-5ja1A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 GLY A 261
HIS A 299
LEU A 309
GLY A 429
GLY A 800
 None
 1.14A 5d4uA-5ja1A:
2.6		 5d4uA-5ja1A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 GLY A 261
HIS A 299
LEU A 309
GLY A 429
GLY A 800
 None
 1.11A 5d4uB-5ja1A:
2.6		 5d4uB-5ja1A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 ALA A 256
LEU A 263
GLY A 261
LEU A 260
LEU A 380
 None
 1.16A 5dqfA-5ja1A:
undetectable		 5dqfA-5ja1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 6 LEU A 726
LEU A 730
LEU A 765
HIS A 743
 None
 0.90A 5gs4A-5ja1A:
undetectable		 5gs4A-5ja1A:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 VAL A 293
LEU A 382
LEU A 349
LEU A 253
THR A 249
 None
 1.14A 5hnwB-5ja1A:
undetectable		 5hnwB-5ja1A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 VAL A 293
LEU A 382
LEU A 349
LEU A 253
THR A 249
 None
 1.22A 5hnyB-5ja1A:
undetectable		 5hnyB-5ja1A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 LEU A 745
GLY A 723
TYR A 852
ASN A 744
LEU A 742
 None
75C  A1301 (-3.4A)
75C  A1301 (-3.8A)
75C  A1301 (-3.3A)
None
 1.50A 5kklB-5ja1A:
2.5		 5kklB-5ja1A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 LEU A1088
LEU A1135
ILE A1057
GLN A1126
 None
 0.94A 5ljbA-5ja1A:
undetectable		 5ljbA-5ja1A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 LEU A 378
LEU A 255
ALA A 256
LEU A 382
 None
 0.87A 5y7pC-5ja1A:
undetectable		 5y7pC-5ja1A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 9 VAL A 510
GLY A 529
VAL A 526
ASP A 506
GLY A 505
 None
 1.35A 5zniA-5ja1A:
undetectable		 5zniA-5ja1A:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 ILE A 417
ALA A 421
GLN A 238
LEU A 239
ILE A 392
 None
 1.15A 6a5zD-5ja1A:
undetectable		 6a5zD-5ja1A:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 LEU A 819
GLU A 750
ARG A 866
LEU B  60
 None
None
75C  A1301 (-4.0A)
None
 0.99A 6cbzA-5ja1A:
undetectable		 6cbzA-5ja1A:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 5 GLU A 670
PRO A1026
THR A1025
GLN A1023
 None
 1.43A 6fgdA-5ja1A:
2.5		 6fgdA-5ja1A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.06A 6r2eA-5ja1A:
undetectable		 6r2eA-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.12A 6r2eB-5ja1A:
undetectable		 6r2eB-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.05A 6r2eC-5ja1A:
undetectable		 6r2eC-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.13A 6r2eD-5ja1A:
undetectable		 6r2eD-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.09A 6r2eF-5ja1A:
undetectable		 6r2eF-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 11 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.10A 6r2eG-5ja1A:
undetectable		 6r2eG-5ja1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 ILE A 867
LEU A 926
ASP A 873
LEU A 869
GLY A 870
 None
 1.20A 6r2eH-5ja1A:
undetectable		 6r2eH-5ja1A:
13.20