SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ja4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5ja4 DNA REPLICATION
LICENSING FACTOR
MCM2
(Homo
sapiens) 		3 / 3 ASP C  80
ARG C  82
ARG C  79
 None
 1.05A 2j9dA-5ja4C:
undetectable
2j9dC-5ja4C:
undetectable		 2j9dA-5ja4C:
22.22
2j9dC-5ja4C:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5ja4 TONSOKU-LIKE PROTEIN
(Homo
sapiens) 		5 / 11 LEU D 617
LEU D 618
LEU D 606
GLY D 573
LEU D 575
 None
 1.29A 3hm1B-5ja4D:
undetectable		 3hm1B-5ja4D:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ja4 TONSOKU-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 HIS D 567
GLU D 568
TRP D 563
 None
 1.20A 5odiD-5ja4D:
undetectable		 5odiD-5ja4D:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ja4 TONSOKU-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 HIS D 567
GLU D 568
TRP D 563
 None
 1.11A 5odqD-5ja4D:
undetectable		 5odqD-5ja4D:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5ja4 TONSOKU-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 HIS D 567
GLU D 568
TRP D 563
 None
 1.18A 5odrD-5ja4D:
undetectable		 5odrD-5ja4D:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 5ja4 TONSOKU-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 ARG D 525
GLY D 529
GLU D 530
 None
 0.63A 6fgdA-5ja4D:
undetectable		 6fgdA-5ja4D:
16.91